Abstract: The subject invention provides a pharmaceutical formulation in the form of an oily solution for injection to a subject comprising a contraceptively and/or therapeutically effective amount of a long-acting progestogen and a contraceptively and/or therapeutically effective amount of a long-acting androgen dissolved in a pharmaceutically acceptable oily medium wherein the injection is administered by the subject itself with a needle-less device, a mini-needle device or a pre-filled subcutaneous syringe.

Abstract: The subject invention provides a contraceptive and/or HRT kit comprising a contraceptively and/or therapeutically effective amount of a long-acting etonogestrel ester with a fatty-chain length of C7-C15.

Abstract: The subject invention provides new progestogen esters and uses thereof.

Abstract: This invention is directed to pharmaceutical compositions for oral administration, wherein the drug or active ingredient is known to have stability problems associated with the use of free fatty acids. The compositions of the invention enhance the solubility of such compounds and improve the storage stability thereof and can be advantageously used in soft-gel and hard-shell capsular formulations. The liquid pharmaceutical compositions, according to the present invention, have a drug dissolved in a liquid vehicle. The liquid vehicle comprising a glyceride of a long chain fatty acid and a lypophilic surfactant having an HLB of less than ten. The composition, according to the invention, is also substantially free of free fatty acids.

Abstract: Disclosed are powdered particulates or granules useful for the preparation of certain psychotropic compounds (e.g. mianserin are mirtazepine). The resulting suspensions and relatively tasteless, do not have a local anaesthetic effect and are easy to suspend. The granules contain the psychotropic compound, a cellulose derivative, polymer, and a filler.

Abstract: The present invention relates to a release system for the simultaneous release of two or more active substances, which system consists of two or more reservoirs which are each separately encased or surrounded by a wall which is permeable to the active substance, the encased reservoirs then being assembled together so that one release system is obtained.