Abstract: A peritoneal dialysis (“PD”) system includes a housing, a PD fluid pump housed by the housing, and a reusable patient line extending from the housing. The reusable patient line includes a distal end configured to be connected to a patient line connector provided by the housing. The PD system also includes at least one reusable PD fluid line extending from the housing, the at least one reusable PD fluid line including a distal end configured to be connected to a PD fluid line connector provided by the housing. The PD system further includes a control unit configured to cause the PD fluid pump to apply a negative pressure to at least one of the reusable patient line or the at least one reusable PD fluid line when connected, respectively, to the patient line connector or the PD fluid line connector.

Abstract: A peritoneal dialysis system includes a housing; a dialysis fluid pump housed by the housing; a patient line extendable from the housing; and a hose reel located within the housing, the hose reel configured to coil the patient line when disconnected from a patient. The patient line may be a dual lumen patient line, wherein the dual lumen patient line is coiled about the hose reel during a disinfection sequence for disinfecting the dual lumen patient line and the dialysis fluid pump.

Abstract: A control system operates (201) an apparatus for extracorporeal blood processing to extract, process and return the blood of an individual while removing fluid from the blood in accordance with a set value for ultrafiltration rate, UFR. The control system further obtains (202) sensor data representing one or more physiological parameters of the individual, and intermittently performs an optimization procedure (203) to generate the set value based on the sensor data. The optimization procedure comprises: evaluating (203A) the sensor data for detection of a limiting physiological status, LPS, sequentially controlling (203B) the apparatus in accordance with a test sequence of UFRs until the LPS is detected for a current UFR, and updating (203C) the set value based on the current UFR for use in operating the apparatus subsequent to the optimization procedure. The control system may perform a series of temporally separated optimization procedures during a treatment session to adapt the UFR to the individual.

Abstract: A connection tube (1) for connecting two tubes (8, 9) of different alloys, wherein the connection tube has a central through-hole extending along a longitudinal axis and comprises a first end portion (2) of a first alloy, a second end portion (3) of a second alloy, and a middle portion (4) which is at least partly double-layered with said second alloy forming an annular inner layer and said first alloy forming an annular outer layer, wherein a metallic bond has been formed between said layers. The inner and outer layers are mechanically interlocked by means of at least one helically extending thread formed in an interface between said layers. The connection tube is manufactured from a base component and an outer component threaded onto the base component to form a work piece, which is hot worked to form a metallic bond.

Abstract: Herein a tubular element (2) is disclosed. The tubular element comprises a first tubular portion (4) comprising a first metal or alloy and a second tubular portion (6) comprising a second metal or alloy. At least a portion of an interface (9) between the first and second tubular portions (4, 6) extends within a fixed diameter range along a longitudinal direction (L) of the tubular element. The second tubular portion (6) comprises a first end portion (8) arranged around the first tubular portion (4). The second tubular portion (6) comprises a sealing surface (10) extending circumferentially around the second tubular portion (6) at the first end portion (8).

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing; a dual lumen patient line extending from the housing; a filter set including a final stage filter located along a first line, and which includes a second line in parallel with the first line, the first line in fluid communication with a first lumen of the dual lumen patient line, and the second line in fluid communication with a second lumen of the dual lumen patient line; a pressure sensor located within the housing and positioned so as to sense a static or substantially static PD fluid pressure in the second lumen while fresh PD fluid is pumped through the first lumen and the final stage filter; and a control unit configured to use the sensed static or substantially static pressure in a pressure control routine for the dialysis fluid pump.

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a dialysis fluid pump housed by the housing and including a reusable pump body that accepts PD fluid for pumping; a dialysis fluid inline heater housed by the housing and including a reusable heater body that accepts PD fluid for heating; at least one reusable PD fluid line extending from the housing; at least one disinfection connector supported by the housing and configured to accept one of the at least one reusable PD fluid line; and a control unit configured to run a disinfection sequence after a PD treatment, wherein each of the at least one reusable PD fluid line is connected to one of the at least one disinfection connectors, and wherein at least one of the dialysis fluid pump or the dialysis fluid inline heater is actuated by the control unit during the disinfection sequence.

Abstract: The present invention relates to systems and methods for filtration and/or dilution of fluids, in particular for the dialysis of blood. The systems comprise a filter device (10) having a fluid chamber (18) and comprising a first lid (20) having arranged thereon a first fluid port (22). The filter device (10) further comprises a second lid (30) having arranged thereon at least a second fluid port (32). The filter device (10) further comprises a plurality of hollow fibers (40) arranged within the housing (12), wherein each of the plurality of hollow fibers (40) comprises a semi-permeable membrane and defines a fluid channel extending longitudinally through an interior of the respective hollow fiber (40). Also, the filter device (10) comprises a fourth fluid port (50) and a fifth fluid port (52) both provided at the fluid chamber (18).

Abstract: Method for manufacturing a composite tube having at least one double-layered portion with an annular outer layer of a first alloy and an annular inner layer of a second alloy provides a base component of the second alloy, having a central through-hole and an externally threaded section, provides an outer component of the first alloy, having an internally threaded section configured to engage with the externally threaded section, forms a tubular work piece by mounting the outer component around the base component such that the internally threaded section is in engagement with the externally threaded section, and hot works the work piece so that a metallic bond is formed between the threaded sections while the mechanical interlock is maintained, and so that the work piece is elongated and its outer diameter is reduced, thus forming a composite tube.

Abstract: Herein a tubular element (2) is disclosed. The tubular element comprises a first tubular portion (4) comprising a first metal or alloy and a second tubular portion (6) comprising a second metal or alloy. At least a portion of an interface (9) between the first and second tubular portions (4, 6) extends within a fixed diameter range along a longitudinal direction (L) of the tubular element. The second tubular portion (6) comprises a first end portion (8) arranged around the first tubular portion (4). The second tubular portion (6) comprises a sealing surface (10) extending circumferentially around the second tubular portion (6) at the first end portion (8).

Abstract: A method for manufacturing a composite tube having at least one double-layered portion with an annular outer layer of a first alloy and an annular inner layer of a second alloy, comprising: —providing a base component (301) of the second alloy, having a central through-hole and an externally threaded section (302), —providing an outer component (401) of the first alloy, having an internally threaded section (402) configured to engage with the externally threaded section, —forming a tubular work piece by mounting the outer component around the base component such that the internally threaded section is in engagement with the externally threaded section, —hot working the work piece so that a metallic bond is formed between the threaded sections while the mechanical interlock is maintained, and so that the work piece is elongated and its outer diameter is reduced, thus forming a composite tube.

Abstract: The present invention relates to systems and methods for filtration and/or dilution of fluids, in particular for the dialysis of blood. The systems comprise a filter device (10) having a fluid chamber (18) and comprising a first lid (20) having arranged thereon a first fluid port (22). The filter device (10) further comprises a second lid (30) having arranged thereon at least a second fluid port (32). The filter device (10) further comprises a plurality of hollow fibers (40) arranged within the housing (12), wherein each of the plurality of hollow fibers (40) comprises a semi-permeable membrane and defines a fluid channel extending longitudinally through an interior of the respective hollow fiber (40). Also, the filter device (10) comprises a fourth fluid port (50) and a fifth fluid port (52) both provided at the fluid chamber (18).

Abstract: A connection tube (1) for connecting two tubes (8, 9) of different alloys, wherein the connection tube has a central through-hole extending along a longitudinal axis and comprises a first end portion (2) of a first alloy, 5 a second end portion (3) of a second alloy, and a middle portion (4) which is at least partly double-layered with said second alloy forming an annular inner layer and said first alloy forming an annular outer layer, wherein a metallic bond has been formed between said layers. The inner and outer layers are mechanically interlocked by means of at 10 least one helically extending thread formed in an interface between said layers. The connection tube is manufactured from a base component and an outer component threaded onto the base component to form a work piece, which is hot worked to form a metallic bond.