Abstract: Disclosed is a method and an auto-injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor.

Abstract: The present invention relates to polypeptide variants and methods for obtaining variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract: Disclosed is an auto injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge assembly comprising a cartridge and a cartridge code feature, the cartridge containing the medicament; a code sensor configured to read the cartridge code feature; a drive module coupled to move a plunger rod; and a processing unit coupled to the code sensor and the drive module. The processing unit being configured to: receive from the code sensor a code signal indicative of the cartridge code feature; control the drive module to move the plunger rod to a first plunger rod position, the first plunger rod position being based on the code signal; receive a trigger event; control the drive module to move the plunger rod to a second plunger rod position following reception of the trigger event.

Abstract: An ultrasound imaging system include a console with transmit circuitry configured to generate an excitation electrical pulse that excites transducer elements of a probe to produce an ultrasound pressure field and configured to receive an echo signal generated in response to the ultrasound pressure field interacting with tissue. The console further includes receive circuitry configured to convert the echo signal into an electrical signal, and an echo processor configured to generate a live ultrasound image based on the electrical signal into. The console further includes a tracking processor configured to extract, in real-time, a feature common to both the live ultrasound image and previously generated volumetric image data from at least the live ultrasound image, and register, in real-time, the live ultrasound image with previously generated volumetric image data based on the common feature extracted in real-time to create the fused image. A display displays the fused image.

Abstract: A method, an assembly and a system for determining a characteristic property of a molecular interaction. The method includes providing a liquid sample including a particle capable of being in a state of equilibrium and in a state of non-equilibrium. The particle includes a marker in at least one of its state of equilibrium and state of non-equilibrium. The method further includes bringing the particle in a state of non-equilibrium by subjecting the sample to a condition jump comprising a jump in temperature and/or pressure; reading out the marker as a function of time during at least a portion of a relaxation time for said particle, and determining said characteristic property of said molecular interaction.

Abstract: A system (502) includes an elongate ultrasound imaging probe (504) with a long axis and a top side that extends along the long axis. The elongate ultrasound imaging probe includes an elongate tubular handle (606; 1606), a head (1608), an elongate tubular shaft (608; 1610) between the elongate tubular handle and the head, and a transducer array (514) disposed in the head and configured to transmit in a sagittal plane, which is a plane that cuts through the long axis of the elongate tubular shaft, only in a direction extending out from the top side. The elongate tubular handle is both not centered on the elongate tubular shaft and not shifted down in the sagittal plane away from the top.

Abstract: A method for determining a property of at least one liquid and an assessment system for performing the method are described. The method includes providing at least a first liquid and a second liquid at least one of these includes a detectable marker; feeding a portion of the first liquid and a portion of the second liquid in succession into a channel to provide an interfacial contact between the first liquid portion and the second liquid portion; obtaining a row of signals by reading out intensity of the marker of a plurality of volume fractions of the first liquid portion and the second liquid portion located at an interface region comprising the interface between the first liquid portion and the second liquid portion and determining the property from the signal row.

Abstract: A method for determining an immunogenic response characteristic of a chemical substance. The method includes obtaining a biological liquid sample including the chemical substance, providing at least one prepared sample from at least a portion of the biological liquid sample, for each prepared sample, subjecting the at least a test portion of the prepared sample to a flow involving that the test portion of the prepared sample is in contact with a binding partner for the chemical substance, wherein the binding partner includes an optical marker, performing at least one read out of the optical marker and based thereon, determining a characteristic flow parameter of the marked binding partner in contact with the prepared sample and comparing the determined characteristic flow parameter with a respective reference value and determining the immunogenic response characteristic of the chemical substance.

Abstract: A method for coating a building panel, the method including applying a first coating fluid including an organic binder on a surface of the building panel to obtain at least one coating layer, and applying barrier components and photocatalytic particles, preferably TiO2, on the at least one coating layer. Also, such a building panel.

Abstract: An inhaler or add-on device for an inhaler for dispensing a medicament to be inhaled. The inhaler or add-on device has a housing (H) with an air inlet (A_I), and an air outlet (A_O) for outputting air to be inhaled by a user. The housing (H) defines a flow path (FP) between the air inlet (A_I) and air outlet (A_O), and a passive acoustic element (PAE) is arranged in this flow path (FP) inside the housing (H). The passive acoustic element (PAE) has a structure having one or more structured gaps arranged to be passed by an air flow and it is dimensioned such that air flow passing it will generate sound (S) with pre-determined characteristics depending on the air flow speed. This allows acoustic monitoring of air flow passing the first passive acoustic element (PAE) external to the housing (H) by capturing and processing sound generated.

Abstract: An inhaler or add-on device for an inhaler for dispensing a medicament to be inhaled. The inhaler or add-on device has a housing (H) with an air inlet (A_I), and an air outlet (A_O) for outputting air to be inhaled by a user. The housing (H) defines a flow path (FP) between the air inlet (A_I) and air outlet (A_O), and a passive acoustic element (PAE) is arranged in this flow path (FP) inside the housing (H). The passive acoustic element (PAE) has a structure having one or more structured gaps arranged to be passed by an air flow and it is dimensioned such that air flow passing it will generate sound (S) with pre-determined characteristics depending on the air flow speed. This allows acoustic monitoring of air flow passing the first passive acoustic element (PAE) external to the housing (H) by capturing and processing sound generated.

Abstract: A method for coating a building panel, including applying a first coating fluid including an organic binder on a surface of the building panel to obtain at least one coating layer, and applying barrier components and photocatalytic particles, preferably TiO2, on the at least one coating layer. Also, a building panel formed by the method.

Abstract: The invention concerns a method, an assembly and a system for determining a characteristic property of a molecular interaction. The method includes providing a liquid sample including a particle capable of being in a state of equilibrium and in a state of non-equilibrium. The particle includes a marker in at least one of its state of equilibrium and state of non-equilibrium. The method further includes bringing the particle in a state of non-equilibrium by subjecting the sample to a condition jump comprising a jump in temperature and/or pressure; reading out the marker as a function of time during at least a portion of a relaxation time for said particle, and determining said characteristic property of said molecular interaction.

Abstract: An ultrasound imaging probe (204) includes a transducer array (210). The transducer array includes one or more transducer elements (212). The ultrasound imaging probe further includes an illumination component (218) and an optical imaging component (220). The ultrasound imaging probe further includes an elongated housing (302) with a long axis (304). The elongated housing includes a proximal end region (306) affixed to a handle (308) and a distal end region (310) with a tip region (312). The elongated housing houses the transducer array, the illumination component, and the optical imaging component in the distal end region.

Abstract: An ultrasound probe includes a housing. The housing includes a first end, which internally houses: a transducer array and a tracking sensor, and a second end. The housing further includes a second portion extending between the first and second ends. The second portion houses: a first electrically conductive path extending from the transducer array through the second portion to the second end, which is opposite the first end, and a second electrically conductive path extending from the tracking sensor through the second portion to the second end. The probe further includes a single electro-mechanical connector with a physical interface configured to transfer signals carried by the first and second electrically conductive members off the probe. The probe further includes a single cable that routes the first and second electrically conductive members from the second end to the electro-mechanical connector.

Abstract: A method of applying a NOx degrading composition on a concrete element, including providing a concrete element having a surface, and applying a composition including photocatalytic titanium dioxide particles dispersed in a continuous phase on the surface of said concrete element. Also, a concrete element having NOx degrading properties. Also, a concrete element having photocatalytic titanium dioxide particles dispersed thereon.

Abstract: The present invention relates to a photocatalytic concrete product and a method to produce a photocatalytic concrete product. In first aspect the invention relates to method of producing photocatalytic concrete product, said concrete product being photocatalytic by containing nano sized photocatalytic particles embedded in an section including a first surface, said first surface forming an exterior surface when the photocatalytic concrete product is used as cover/lining. The method comprises: providing a not-yet-set concrete product having a first surface, applying a dispersion containing nano sized photocatalytic particles, such as titanium dioxide nanoparticles a solvent including a humectant onto said first surface of the not-yet-set concrete product.

Abstract: An ultrasound imaging system (102) includes a transducer array (108) with a two-dimensional non-rectangular array of rows (110) of elements, transmit circuitry (112) that actuates the elements to transmit an ultrasound signal into a field of view, receive circuitry (114) that receives echoes produced in response to an interaction between the ultrasound signal and a structure in the field of view, and a beamformer that processes the echoes, thereby generating one or more scan lines indicative of the field of view.

Abstract: A system (502) includes an elongate ultrasound imaging probe (504) with a long axis and a top side that extends along the long axis. The elongate ultrasound imaging probe includes an elongate tubular handle (606; 1606), a head (1608), an elongate tubular shaft (608; 1610) between the elongate tubular handle and the head, and a transducer array (514) disposed in the head and configured to transmit in a sagittal plane, which is a plane that cuts through the long axis of the elongate tubular shaft, only in a direction extending out from the top side. The elongate tubular handle is both not centered on the elongate tubular shaft and not shifted down in the sagittal plane away from the top.

Abstract: An ultrasound imaging system (102) includes a transducer array (108) with a two-dimensional array of rows (110) of transducer elements (114). The transducer elements of each row extend along a long axis (116). The rows are parallel to each other. The transducer array includes a non-rectangular set of active transducer elements. The ultrasound imaging system further includes transmit circuitry (118) that actuates the transducer elements to transmit an ultrasound signal. The ultrasound imaging system further includes receive circuitry (120) that receives echoes produced in response to an interaction between the ultrasound signal and a structure and received by the transducer elements. The ultrasound imaging system further includes a beamformer that processes the echoes and generates one or more scan lines indicative of the structure.