Patents by Inventor Henrik Ostlin

Henrik Ostlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10421074
    Abstract: The present invention provides a microplate comprised of multiwell strips connected in such a way as to permit the microplate to unfold and to pass in a linear fashion past a fraction collector and then re-fold back into a microplate configuration. Furthermore, the invention provides for the use of the microplates of the invention in a variety of different laboratory methods.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: September 24, 2019
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Nils Norrman, Henrik Ostlin
  • Patent number: 9987628
    Abstract: The present invention provides methods and systems for eluting and an analyte from a solid phase. The invention further provides methods and systems for transferring liquid analyte reagent mixtures from a solid phase to a second vessel, such as a microtiter plate well. The invention is useful in the manipulation of biological molecules such as nucleic acids, carbohydrates, proteins and peptides. In particular, the invention has utility for manipulating proteins and peptides in isoelectric focusing gels.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: June 5, 2018
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Tobias Ingemar Solderman, Nils Norrman, Henrik Ostlin, Susanna Lindman, David Carl Martin Bergman, Peter Mats Oliviusson
  • Publication number: 20160303559
    Abstract: The present invention provides methods and systems for eluting and an analyte from a solid phase. The invention further provides methods and systems for transferring liquid analyte reagent mixtures from a solid phase to a second vessel, such as a microtitre plate well. The invention is useful in the manipulation of biological molecules such as nucleic acids, carbohydrates, proteins and peptides. In particular, the invention has utility for manipulating proteins and peptides in isoelectric focusing gels.
    Type: Application
    Filed: November 26, 2014
    Publication date: October 20, 2016
    Inventors: Tobias Ingemar Solderman, Nils Norrman, Henrik Ostlin, Susanna Lindman, David Carl Martin Bergman, Peter Mats OLIVIUSSON
  • Publication number: 20160303561
    Abstract: The present invention provides a microplate comprised of multiwell strips connected in such a way as to permit the microplate to unfold and to pass in a linear fashion past a fraction collector and then re-fold back into a microplate configuration. Furthermore, the invention provides for the use of the microplates of the invention in a variety of different laboratory methods.
    Type: Application
    Filed: November 25, 2014
    Publication date: October 20, 2016
    Inventors: Nils Norrman, Henrik Ostlin
  • Patent number: 9383335
    Abstract: Electrophoresis gel cassette comprising a first and a second face wall member and one or more side wall members defining a gel compartment for a gel member with a first and second face, wherein at least a section of each one of the first and second face wall member is removable to expose a section of both the first and second face of the gel member essentially corresponding to the separation zone while the gel member is preserved in the cassette.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: July 5, 2016
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Lennart Bjorkesten, Owe Salven, Camilla Larsson, Erik J Bjerneld, Sofia Edlund, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Ola Ronn, Peter Oliviusson, Henrik Bjorkman
  • Patent number: 9377436
    Abstract: Electrophoresis gel cassette comprising a cassette housing defining a gel compartment for molding a gel member wherein the gel compartment comprises a fill port at an inlet end of the gel compartment and one or more over-fill ports at a distal end of the gel compartment with respect to a filling direction, and wherein the over-fill port(s) is arranged in fluidic communication with an overfill chamber.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: June 28, 2016
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Owe Salven, Camilla Larsson, Stefan Ogeus, Henrik Ostlin, Stefan Sjolander, Malin Eriksson
  • Patent number: 9360452
    Abstract: Electrophoresis tray arranged to support an electrophoresis cassette for miming electrophoresis experiments, the electrophoresis cassette comprising a gel member in a housing with a front and a back face, wherein the tray comprises a cassette support surface for supporting at least the separation zone of the electrophoresis cassette during electrophoresis, and wherein the cassette support surface is flanked by a pair of buffer pad holders each one arranged to hold a buffer pad in a mating position with respect to buffer connection sections at the back face of the electrophoresis cassette.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: June 7, 2016
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Owe Salven, Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Peter Oliviusson, Tomas Haukkala, Kjell Larsson, Anders Jahge
  • Patent number: 9341595
    Abstract: An electrophoresis gel assembly comprising a gel slab, at least two sample wells and at least one focusing buffer well arranged between two adjacent sample wells and wherein focusing barriers are arranged between the focusing buffer well and the sample wells. A high conductivity focusing buffer can be applied to the focusing buffer well to obtain a lateral focusing of the sample bands during electrophoresis.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: May 17, 2016
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Bengt Bjellqvist, Elsemarie Bjellqvist, Henrik Ostlin
  • Publication number: 20150219597
    Abstract: Electrophoresis system comprising at least one type of electrophoresis gel card, at least one type of blot membrane card, an electrophoresis apparatus for running electrophoresis experiments using the electrophoretic gel card, a blot transfer unit for transfer of separated sample from the electrophoresis gel card to the blot membrane card, an imaging apparatus for recording images of separated sample in the electrophoresis gel card and the blot membrane card, wherein; the electrophoresis gel card and the blot membrane card each comprises a rigid support provided with an alignment structure defining a positional reference for mutual alignment during transfer, and for alignment with respect to a complementary alignment structure in the imaging apparatus to provide mechanically aligned images of separated sample in the electrophoresis gel card and the blot membrane card.
    Type: Application
    Filed: May 31, 2013
    Publication date: August 6, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Anders Jahge, Kajas Stridsberg-Friden
  • Publication number: 20150192542
    Abstract: Method of manufacturing an electrophoresis gel cassette with a cassette housing defining a gel compartment for molding a gel member,comprising the steps of: molding in a rigid material a cassette housing member with an external face, an internal face defining at least a section of the gel compartment, and at least one opening for providing access to the gel compartment from the external face, and molding a closing member formed to close the at least one opening of the cassette housing member at the external face, wherein the closing member is molded with the cassette housing member acting partly as mold, and is comprised of an elastic material with non-permanent adhesion to the rigid material to make the closing member selectively removable.
    Type: Application
    Filed: May 31, 2013
    Publication date: July 9, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Anders Jahge, Kajas Stridsberg-Friden
  • Publication number: 20150185181
    Abstract: Electrophoresis gel cassette comprising a first and a second face wall member and one or more side wall members defining a gel compartment for a gel member with a first and second face, wherein at least a section of each one of the first and second face wall member is removable to expose a section of both the first and second face of the gel member essentially corresponding to the separation zone while the gel member is preserved in the cassette.
    Type: Application
    Filed: May 31, 2013
    Publication date: July 2, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Lennart Bjorkesten, Owe Salven, Camilla Larsson, Erik J. Bjerneld, Sofia Edlund, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Ola Ronn, Peter Oliviusson, Henrik Bjorkman
  • Publication number: 20150177186
    Abstract: Electrophoresis gel unit comprising a flat gel member with an upper and a lower face and a sample separation zone, wherein the gel member is attached to a rigid support arranged to preserve the shape of and to facilitate handling of the gel member, wherein the rigid support is formed to allow access to a section of both the upper and lower face of the gel member essentially corresponding to the separation zone.
    Type: Application
    Filed: May 31, 2013
    Publication date: June 25, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Lennart Bjorkesten, Owe Salven, Camilla Larsson, Erik J. Bjerneld, Sofia Edlund, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Ola Ronn, Peter Oliviusson, Henrik Bjorkman
  • Publication number: 20150160155
    Abstract: Electrophoresis gel cassette comprising a cassette housing defining a gel compartment for molding a gel member wherein the gel compartment comprises a fill port at an inlet end of the gel compartment and one or more over-fill ports at a distal end of the gel compartment with respect to a filling direction, and wherein the over-fill port(s) is arranged in fluidic communication with an overfill chamber.
    Type: Application
    Filed: May 31, 2013
    Publication date: June 11, 2015
    Inventors: Owe Salven, Camilla Larsson, Stefan Ogeus, Henrik Ostlin, Stefan Sjolander, Malin Eriksson
  • Publication number: 20150144492
    Abstract: Electrophoresis gel cassette comprising a first and a second face wall member and one or more side wall members, defining a gel compartment for a gel member with a first and second face, wherein the first face wall member has high gel adhesion compared to the second face wall member, whereby a gel member molded in the cassette will stay attached to the high gel adhesion face wall member when the cassette is opened, and wherein the first face wall member is provided with at least one removable section to expose a section of the first face of the gel member, the removable section of the first face wall member having lower gel adhesion compared to the non-removable part of the first face wall member.
    Type: Application
    Filed: May 31, 2013
    Publication date: May 28, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Lennart Bjorkesten, Owe Salven, Camilla Larsson, Erik J Bjerneld, Sofia Edlund, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Ola Ronn, Peter Oliviusson, HENRIK Bjorkman
  • Publication number: 20130168248
    Abstract: An electrophoresis gel assembly comprising a gel slab, at least two sample wells and at least one focusing buffer well arranged between two adjacent sample wells and wherein focusing barriers are arranged between the focusing buffer well and the sample wells. A high conductivity focusing buffer can be applied to the focusing buffer well to obtain a lateral focusing of the sample bands during electrophoresis.
    Type: Application
    Filed: January 10, 2011
    Publication date: July 4, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Henrik Ostlin, Elsemarie Bjellqvist
  • Publication number: 20110124106
    Abstract: A separation device for separating a wanted end product from a liquid sample comprises a container (2) having a first end (5) and a second end (7), the first end having a central orifice (6), a plunger (3) slideably disposed in the container (2) to define a variable liquid receiving chamber between the plunger (3) and the orifice (6), and a permeable partition member (9) mounted to the plunger (3) in a spaced relationship thereto to define a compartment (12) between the partition member (9) and the plunger (3) for receiving liquid density gradient medium (13), wherein liquid may be drawn into the container (2) and expelled therefrom, respectively, through the orifice (6) by movement of the plunger (3) relative to the container (2). A method for separating a wanted end product from a liquid sample is also disclosed.
    Type: Application
    Filed: July 20, 2009
    Publication date: May 26, 2011
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Gunnar Froman, Henrik Ostlin
  • Publication number: 20100120596
    Abstract: A separation device adapted for separation of a wanted end product from a sample by centrifugation. According to the invention the device comprises: a first, a second and a third compartment; a first fluid connection between the first and second compartments, arranged to be opened and closed by first closing means; a second fluid connection between the second and the third compartments, arranged to be opened and closed by second closing means. The separation device is adapted to be subjected to centrifugation after having been filled with a first density gradient medium in the first compartment, sample in the third compartment and a second density gradient medium or sample in the second compartment, whereby after centrifugation the wanted end product will settle in the second compartment and the first fluid connection and the second fluid connection will be closed by the first closing means and the second closing means respectively.
    Type: Application
    Filed: May 8, 2008
    Publication date: May 13, 2010
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Gunnar Froman, Lars Haneskog, Bjorn A. Johansson, Henrik Ostlin
  • Patent number: 7295320
    Abstract: A detector arrangement, which comprises a rotatable microfluidic disc and a spectrophotometric detector unit. The arrangement is characterized in that the detector unit is based on surface plasmon resonance (SPR) and is capable of measuring an analyte within the detection microcavities, each of which is part of a microchannel structure. A microfluidic disc having an axis of symmetry and comprising microchannel structures, each of which has an upstream functional part that is at a shorter radial position than a downstream functional part. The disc is characterized in that there are detection microcavities (DMCs) in at least a part of said microchannel structures, and that each of said DMCs has an SPR surface on an inner wall and a detection detection window extending from the SPR surface to the surface of the disc.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: November 13, 2007
    Assignee: Gyros AB
    Inventors: Henrik Ostlin, Lars Eriksson, Magnus Ljungstrom, Tomas Agren
  • Patent number: 7169360
    Abstract: The invention relates to a rotary drive adapted for creating liquid flow in rotatable microfluidic discs. A rotary drive for spinning a disc shaped substrate having microfluidic structures formed therein for the flow control of microliter and/or nanoliter volumes of liquid by centrifugal force is suggested, comprising a motor with a spindle having an axis of rotation. A rotary member is connected for rotation with the spindle and driven for rotation relative to a stationary member, the rotary member being formed with a top plane having a centering guide for receiving the disc so as to force a symmetry axis of the disc into alignment with said axis of rotation. A vacuum source is connected with the stationary member and communicating with the rotary member or a part thereof rotating with the rotary member for applying sub-pressure to the disc when spinning the disc about its symmetry axis. Preferably, the rotary member is journalled for contact-free rotation relative to the stationary member.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: January 30, 2007
    Assignee: Gyros AB
    Inventors: Tomas Ågren, Henrik Östlin
  • Patent number: D595423
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: June 30, 2009
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Bjorn A. Johansson, Nils Norrman, Henrik Ostlin, Sven Wounder