Abstract: Techniques for controlling the yaw of a wind turbine system by controlling a plurality of yaw drive actuators. Based on a requested motor speed reference as an input signal, and a mean motor speed reference as a feedback signal, the method determines a required motor torque reference as an output signal for the plurality of yaw drive actuators. The plurality of yaw drive actuators rotates a nacelle or a structure comprising a plurality of nacelles such that an even load distribution is provided for the plurality of yaw drive actuators.

Abstract: Systems, methods, and computer program products for controlling a yaw system of a wind turbine. The yaw system includes mechanical brakes that provide a first amount of braking torque when closed. The yaw system is configured to transition from a yawing state to a parked by brake state by closing mechanical brakes in a first subset of the mechanical brakes and opening each mechanical brake in a second subset of the mechanical brakes. The second subset provides a second amount of braking torque that is less than the first amount of braking torque. In response to detecting a rotation of the nacelle while in the parked by brake state, the yaw system is configured to transition from the parked by brake state to a parked by motor state in which yaw drives are activated to provide a counter acting torque in opposition to the detected rotation of the nacelle.

Abstract: Composite material units (CMU) of the structure (SE1-ML-LinkerL-Ligand2-SE2), are provided, wherein ML is a Mechanical Ligand, LinkerL is a chemical bond or entity that covalently links ML and Ligand2, Ligand2 is a chemical entity that is covalently linked to the structural entity SE2, or forms a mechanical bond with the structural entity SE2, and SE1 and SE2 are structural entities.

Abstract: The present application relates to a fusion protein comprising: an antibody or antigen-binding fragment thereof that binds to C3b; and a polypeptide that binds to C3b, wherein the polypeptide comprises: (i) the amino acid sequences according to SEQ ID NO: 11 or a variant thereof having at least 80% sequence identity to the amino acid sequence according to SEQ ID NO: 11; and (ii) the amino acid sequences according to SEQ ID NO: 12 or a variant thereof having at least 80% sequence identity to the amino acid sequence according to SEQ ID NO: 12, wherein the antibody or antigen-binding fragment thereof of the fusion protein does not compete for binding to C3b with the polypeptide of the fusion protein. The application also provides polypeptides, nucleic acids, vectors and methods of preparing these as well as methods of treatment and pharmaceutical compositions.

Abstract: The present invention relates to methods for construction of pharmamers i.e. vaccine components characterized by their multimerization domain and the attached biologically active molecules, and their use in preparation of vaccines that contains the pharmamers alone or in combination with other molecules. The individual molecules of the construct can be bound to each other or the multimerization domain(s) by covalent or non-covalent bonds, directly or via linkers. The invention further relates to the use of such preparations in vaccine settings aimed to function as preventive/prophylactic or therapeutic vaccines in humans and animals.

Abstract: Single domain antibodies are provided, which are capable of specifically binding to an epitope of a human complement factor selected from the group consisting of C1q, C3, C4 and/or the proteolytic derivatives C3b and C4b. Further the use of the antibodies are provided for methods in modulating the activity of the complement system as well 5 as methods of treating disorders associated with complement activation.

Abstract: In some examples, as part of implementing a service on a communication infrastructure that includes multiple different types of network domains, a system creates a distributed cloud of network functions, where the network functions are executable in virtualized environments on the physical resources to perform respective tasks. The system establishes a connection between the network functions to provide the service as part of service orchestration in the communication infrastructure, the service including the respective tasks of the network functions. Communication of data between the network functions includes translating, at an edge of the distributed cloud, domain-specific data packets according to protocols used in the multiple different types of network domains to domain-agnostic data packets comprising labels to support label-based forwarding of data packets between the network functions in the virtualized environments.

Abstract: This invention describes the production and properties of a pMHC Multiplexer. The pMHC Multiplexer is a spatially limited composition of two different molecules, an encoding molecule (i.e. an RNA or DNA molecule), and an encoded peptide, where said encoded peptide is encoded by said encoding molecule. Furthermore, the peptide is complexed to a MHC complex and thus is part of a pMHC complex. A preferred embodiment of the invention describes the production and properties of an example pMHC Multiplexer that is a phage particle carrying on its surface a number of identical pMHC complexes, where the peptide of the pMHC complexes is encoded by the DNA contained within the phage particle, and where a covalent or non-covalent bond links a phage coat protein with a pMHC complex and/or a pMHC Multimer.

Abstract: The present invention relates to detection molecules comprising at least one binding molecule, at least one linker and at least one label, and detection methods making use of same. The invention provides a high-throughput method for detection, isolation and/or identification of specific entities or cells.

Abstract: Techniques for controlling the yaw of a wind turbine system by controlling a plurality of yaw drive actuators. When the yaw drive actuators are applying the same torque to all the motors, this can lead to some motors overspeeding, if the motor is not engaged when the yaw system is activated. Therefore, if the actual motor speed reference of a yaw drive actuator is higher than a specific motor speed reference, then an output signal to reduce the actual motor speed reference is applied to the yaw drive actuators with an actual motor speed reference higher than the specific motor speed reference.

Abstract: The present invention relates to methods for construction of pharmamers i.e. vaccine components characterized by their multimerization domain and the attached biologically active molecules, and their use in preparation of vaccines that contains the pharmamers alone or in combination with other molecules. The individual molecules of the construct can be bound to each other or the multimerization domain(s) by covalent or non-covalent bonds, directly or via linkers. The invention further relates to the use of such preparations in vaccine settings aimed to function as preventive/prophylactic or therapeutic vaccines in humans and animals.

Abstract: This invention describes the formation and use of collections of pMHC Multiplexers. A pMHC Multiplexer is a spatially confined composition of at least two molecules, an encoding molecule and a peptide (and/or protein) that is encoded by said encoding molecule. Said at least two molecules are functionally linked, and the properties of the functional link determines the boundaries of the spatial confinement.

Abstract: The present invention describes novel methods to generate MHC multimers and methods to improve existing and new MHC multimers. The invention also describes improved methods for the use of MHC multimers in analysis of T-cells in samples including diagnostic and prognostic methods. Furthermore, the use of MHC multimers in therapy are described, e.g. anti-tumour and anti-virus therapy, including isolation of antigen specific T-cells capable of inactivation or elimination of undesirable targeT-cells or isolation of specific T-cells capable of regulation of other immune cells.

Abstract: The present disclosure relates to a method for chemical vapour deposition on a substrate, the method comprising a precursor step and a reactant step, wherein the precursor step comprises chemisorbing a layer of precursor molecules on the substrate (170), and wherein the reactant step comprises adding to at least part of the substrate (170) surface species able to reduce the precursor molecule, whereby at least a part of the reduced precursor molecule is deposited on the substrate (170) surface, characterized by applying by means of a voltage source (130) a positive bias to at least part of the substrate (170) surface during at least part of the reactant step, wherein the step of adding the reducing species comprises providing by means of an electron source (150) electrons as free particles, whereby during the reactant step a closed electrical circuit is formed as the free electrons are transmitted to the substrate (170) surface.

Abstract: A novel CVD method for preparing a layer including refractory carbide crystals, silicon carbide crystals, wherein at least part of the layer is formed from a gas mixture containing a silicon source and an aromatic carbon source, wherein the molar C/Si ratio in said gas mixture is from about 0.85 to about 1.45. Also, layers obtainable by the method and their various uses and applications.

Abstract: A type of composite material where the matrix material and additive are held together by covalently or non-covalently bound ligands is described. A particularly useful composite material covered by the present invention is a carbon nanotube-reinforced composite material where the matrix consists of a polymer, covalently attached to a linker, where said linker is non-covalently attached to the carbon nanotube. Methods for the preparation of such composite materials are provided.

Abstract: The present invention pertains to a new type of high protein, fruit flavoured beverage comprising fruit flavouring agents and high protein denatured whey protein compositions, and to a method of producing the beverage. The invention particularly pertains to fruit flavoured beverages having a protein content of at least 4% (w/w). The invention furthermore relates to high protein fruit and/or vegetable preparations which e.g. are advantageous for the production of high protein, fruit- and/or vegetable-flavoured yoghurt. The invention also relates to food products containing the high protein fruit and/or vegetable preparations and to method for producing these.