Patents by Inventor Henrik Rajesh Kumar PARSHAD

Henrik Rajesh Kumar PARSHAD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240025979
    Abstract: The present invention relates to stable and low viscosity liquid pharmaceutical compositions comprising antibodies binding to human alpha synuclein and to methods for use of antibodies binding to human alpha synuclein for treating synucleinopathies or prodromal synucleinopathy, incl. suitable doses and/or dosing regimens. These antibodies for use in treatment of synucleinopathies or prodromal synucleinopathy may be formulated in the stable and low viscosity liquid pharmaceutical compositions of the invention.
    Type: Application
    Filed: June 26, 2023
    Publication date: January 25, 2024
    Inventors: Josefine NIELSEN SØDERBERG, Pekka Kallunki, Louise Buur, Frank Larsen, Henrik Rajesh Kumar Parshad, Anne Sofie Markussen, Mark Cornell Manning, Derrick Spencer Katayama, Magdalena Gauden, John Smith
  • Publication number: 20220031810
    Abstract: Liquid formulations of GLP-2 analogues are described that make it possible to include a preservative while allowing the formulation to be stabilised for long term storage as liquids and/or as multi-dose liquid formulations. The development of these formulations is base on the finding that that reducing the pH of the formulation to below 7.0, e.g. to a pH between about pH 5.0 and about 6.8, was able to offset the effect that the addition of a preservative such as meta-cresol has on the physical stability of the formulation. Additionally, the addition of an excipient such as propylene glycol was shown to be able to offset the effect that the addition of a preservative, such as meta-cresol, has on the physical stability of the formulation. This opens up the possibility of being able to deliver the GLP-2 analogues as multi-dose formulations, for example allowing the use of the formulations in a drug delivery device.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 3, 2022
    Inventors: Henrik Rajesh Kumar PARSHAD, Lise GIEHM, Claes MELANDER