Patents by Inventor Henry A. Graham
Henry A. Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11513255Abstract: Disclosed is a method of conditioning one or more parametric models. The method comprises obtaining a plurality of candidate parametric models, each describing a sequence of domains characterising a subsurface region and determining whether each sequence of domains described by one or more of said candidate parametric models is a valid sequence of domains. For each valid sequence of domains, each candidate parametric model describing that valid sequence of domains (or a subset of these models) is conditioned simultaneously, for example by using an Ensemble Kalman Filter or artificial neural network.Type: GrantFiled: April 3, 2017Date of Patent: November 29, 2022Assignee: TOTAL SEInventors: Jiazuo Zhang, Gavin Henry Graham
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Publication number: 20200124764Abstract: Disclosed is a method of conditioning one or more parametric models. The method comprises obtaining a plurality of candidate parametric models, each describing a sequence of domains characterising a subsurface region and determining whether each sequence of domains described by one or more of said candidate parametric models is a valid sequence of domains. For each valid sequence of domains, each candidate parametric model describing that valid sequence of domains (or a subset of these models) is conditioned simultaneously, for example by using an Ensemble Kalman Filter or artificial neural network.Type: ApplicationFiled: April 3, 2017Publication date: April 23, 2020Applicant: Total SAInventors: Jiazuo ZHANG, Gavin Henry GRAHAM
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Patent number: 10107811Abstract: Methods for detecting the presence or absence of, and for quantifying, one set of cells in a mixed cell population of at least two sets of cells especially Rh positive cells in a mixed population with Rh negative cells, as is found in a fetal maternal hemorrhage (FMH). The magnetic particles coated with anti-D antibodies are reacted with the Rh positive fetal cells in Rh negative maternal blood followed by a specific separation and quantifying technique. Gravitational forces or magnetic forces are used to move reacted magnetic particles to isolate, distinguish and quantify cells differentiated by antigenic composition. Rh positive cell volume is correlated to the volume of the original blood sample as an indication of the number of doses of RhIG needed to be administered to the mother to prevent subsequent Rh immunization.Type: GrantFiled: November 4, 2015Date of Patent: October 23, 2018Assignee: Chrome Red Technologies, LLCInventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 9766256Abstract: Methods for separating, cells, particles, or other molecules of interest (MOI) from unwanted materials not of interest (MNOI). by forced movement of MOI into certain zones having properties which deter the entry of unwanted materials. MOI are tagged with magnetic particles and moved with a magnetic field through a fluid, or zones, of higher specific gravity that prevents, unwanted less dense materials from entering. Buoyant or other forces are used to remove any unbound material from the complexes with ASG before reading. Readable labels include the magnetic particle tagged complex itself, and other labels such as enzymes, chemiluminescent materials, radioactive isotopes, chromogenic and fluorogenic substrates and other labels may be used. The invention applies to many assays, diagnostic tests, separative procedures and chemical syntheses.Type: GrantFiled: September 22, 2016Date of Patent: September 19, 2017Assignee: CHROME RED TECHNOLOGIES, LLCInventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Publication number: 20170016922Abstract: Methods for separating, in a continuous, multizone fluid medium, cells, particles, or other molecules of interest (MOI) from associated or contaminating unwanted materials not of interest (MNOI). The invention involves forced movement of MOI into certain zones having properties which deter the entry of unwanted materials. Differential movement of MOI and MNOI occurs by active counterforces that move MNOI but not MOI. MOI are tagged with magnetic particles and moved with a magnetic field through a fluid, or zones, of higher specific gravity that prevents, by flotation counterforce, unwanted less dense materials from entering. Surfaces specifically coated with reactants are reactive with the MOI in the tagged magnetic particle complex and of buoyant or other forces are used to remove any unbound material from the surface before reading.Type: ApplicationFiled: September 22, 2016Publication date: January 19, 2017Inventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 9518984Abstract: Method for detecting a material of interest, usually an antibody or an antigen on a red blood cell, in a liquid, by observing the potential antigen/antibody reaction products in a novel way. Reaction products are deposited on a magnetic substrate and will exhibit different properties depending upon whether or not the antigen/antibody reaction has taken place. An antigen/antibody reaction product adheres tenaciously to itself and the substrate while the deposit of any unreacted magnetically tagged material is weakly adhering and easily disrupted and dislodged under a disruptive force which would be insufficient to dislodge the reacted deposit. This difference in cohesive property provides the means by which a positive result is distinguished from a negative result.Type: GrantFiled: February 21, 2012Date of Patent: December 13, 2016Assignee: CHROME RED TECHNOLOGIES, LLCInventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 9488665Abstract: Methods for separating, in a continuous, multizone fluid medium, cells, particles, or other molecules of interest (MOI) from associated or contaminating unwanted materials not of interest (MNOI). The invention involves forced movement of MOI into certain zones having properties which deter the entry of unwanted materials. Differential movement of MOI and MNOI occurs by active counterforces that move MNOI but not MOI. MOI are tagged with magnetic particles and moved with a magnetic field through a fluid, or zones, of higher specific gravity that prevents, by flotation counterforce, unwanted less dense materials from entering. Surfaces specifically coated with reactants are reactive with the MOI in the tagged magnetic particle complex and of buoyant or other forces are used to remove any unbound material from the surface before reading.Type: GrantFiled: March 8, 2007Date of Patent: November 8, 2016Assignee: CHROME RED TECHNOLOGIES, LLCInventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Publication number: 20160069877Abstract: Methods for detecting the presence or absence of, and for quantifying, one set of cells in a mixed cell population of at least two sets of cells especially Rh positive cells in a mixed population with Rh negative cells, as is found in a fetal maternal hemorrhage (FMH). The magnetic particles coated with anti-D antibodies are reacted with the Rh positive fetal cells in Rh negative maternal blood followed by a specific separation and quantifying technique. Gravitational forces or magnetic forces are used to move reacted magnetic particles to isolate, distinguish and quantify cells differentiated by antigenic composition. Rh positive cell volume is correlated to the volume of the original blood sample as an indication of the number of doses of RhIG needed to be administered to the mother to prevent subsequent Rh immunization.Type: ApplicationFiled: November 4, 2015Publication date: March 10, 2016Inventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 9182389Abstract: Detection of the presence or absence of, RH positive cells in a mixed population with Rh negative cells, as is found in a fetal maternal hemorrhage (FMH). The novel methods utilize gravitational forces or applying magnetic forces to reactive magnetic particles to isolate, distinguish and quantify cells. Particles aggregate and are pulled or settle by gravity through a transparent separating solution into a measuring zone where the volume of Rh positive cells can be measured. Rh positive cell volume is correlated to the volume of the original blood sample as an indication of the number of doses of RhIG needed to be administered to the mother to prevent subsequent Rh immunization.Type: GrantFiled: February 21, 2012Date of Patent: November 10, 2015Assignee: Chrome Red Technologies, LLCInventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 9087060Abstract: A host devices transfers client data from a client device to the host device. The host device generates sort keys for host data that includes the client data. The host device sorts the host data using the sort keys and transfers the sorted host data to the client device. The client data and host data may include music, video, or other content.Type: GrantFiled: March 19, 2012Date of Patent: July 21, 2015Assignee: Apple Inc.Inventors: Thomas Matthieu Alsina, Henry Graham Mason
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Publication number: 20120311194Abstract: A host devices transfers client data from a client device to the host device. The host device generates sort keys for host data that includes the client data. The host device sorts the host data using the sort keys and transfers the sorted host data to the client device. The client data and host data may include music, video, or other content.Type: ApplicationFiled: March 19, 2012Publication date: December 6, 2012Inventors: Thomas Matthieu Alsina, Henry Graham Mason
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Publication number: 20120240931Abstract: Breathing apparatus (10) for high altitude climbing is provided and comprises: a compressor (30) for generating compressed air; means (50) for delivering air at approximately standard atmospheric pressure to a climber; and a power source (20) for powering the compressor.Type: ApplicationFiled: December 3, 2010Publication date: September 27, 2012Inventor: Henry Graham Cornelius Shelford
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Publication number: 20120214175Abstract: Method for detecting a material of interest, usually an antibody or an antigen on a red blood cell, in a liquid, by observing the potential antigen/antibody reaction products in a novel way. Reaction products are deposited on a magnetic substrate and will exhibit different properties depending upon whether or not the antigen/antibody reaction has taken place. An antigen/antibody reaction product adheres tenaciously to itself and the substrate while the deposit of any unreacted magnetically tagged material is weakly adhering and easily disrupted and dislodged under a disruptive force which would be insufficient to dislodge the reacted deposit. This difference in cohesive property provides the means by which a positive result is distinguished from a negative result.Type: ApplicationFiled: February 21, 2012Publication date: August 23, 2012Inventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Publication number: 20120214176Abstract: Methods for detecting the presence or absence of, and for quantifying, one set of cells in a mixed cell population of at least two sets of cells especially Rh positive cells in a mixed population with Rh negative cells, as is found in a fetal maternal hemorrhage (FMH). The magnetic particles coated with anti-D antibodies are reacted with the Rh positive fetal cells in Rh negative maternal blood followed by a specific separation and quantifying technique. Gravitational forces or magnetic forces are used to move reacted magnetic particles to isolate, distinguish and quantify cells differentiated by antigenic composition. Rh positive cell volume is correlated to the volume of the original blood sample as an indication of the number of doses of RhIG needed to be administered to the mother to prevent subsequent Rh immunization.Type: ApplicationFiled: February 21, 2012Publication date: August 23, 2012Inventors: Henry A. Graham, John G. Gorman, James P. Rowell
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Patent number: 7578122Abstract: A rocket motor case includes a plurality of plank sections which provide a structural key for locking metal and/or composite end enclosures in place as part of the motor case. The plank sections are sized longitudinally to form venting spaces in the motor case sidewall to allow passive venting in the event of propellant ignition during cook-off. The plank sections have plank legs which are surrounded by tailorable roll-bonded sheet material to complete formation of the motor case sidewall.Type: GrantFiled: February 26, 1997Date of Patent: August 25, 2009Assignee: Aerojet General CorporationInventors: Irving Edward Figge, Sr., Phillip Henry Graham
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Patent number: 7489642Abstract: The apparatus and method herein provide a means for actively monitoring a communications node for datapath disruptions caused within the node. It was developed to address linecard failures that were detected in the field and for which traditional error detection mechanisms such as CRC and OAM CC checks are not feasible. According to one implementation, statistics are collected over a preset time interval. If any egress cell counts are zero over a full interval, then the ingress interface for that datapath is determined, e.g. using the node's cross-datapath information, and the corresponding linecard of that ingress interface is contacted to determine the ingress cell count. If the ingress cell count is non-zero then the datapath is alarmed since the complete lack of cells transmitted at the egress indicates a datapath disruption.Type: GrantFiled: April 29, 2004Date of Patent: February 10, 2009Assignee: Alcatel LucentInventors: Desmond Glenn Smith, Terrence Vincent Sellars, Stephen Michael Shortt, David Henry Graham, Christopher Edward Trader, Myles Kevin Dear, Thomas Man Chun Kam
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Patent number: 7484353Abstract: A rocket motor case includes a plurality of plank sections which provide a structural key for locking metal and/or composite end enclosures in place as part of the motor case. The plank sections are sized longitudinally to form venting spaces in the motor case sidewall to allow passive venting in the event of propellant ignition during cook-off. The plank sections have plank legs which are surrounded by tailorable roll-bonded sheet material to complete formation of the motor case sidewall.Type: GrantFiled: July 21, 1998Date of Patent: February 3, 2009Assignee: Aerojet-General CorporationInventors: Irving Edward “Ward” Figge, Sr., Phillip Henry Graham
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Patent number: 7451387Abstract: Apparatus and methods for autonomously identifying and mitigating soft-errors affecting integrated circuit memory storage devices are provided. A soft-error mitigation process is invoked upon finding that an integrated circuit memory device is affected by a parity error. In a staged approach, unused memory regions of the integrated circuit memory device are reinitialized; if a redundant deployment prevails, the subsystem corresponding to the affected integrated circuit memory device is reset; memory regions having copies of contents thereof stored at remote locations are rewritten with obtained copies of the contents; and memory regions storing contents which are generated at run-time are reinitialized. Directed parity error scans are employed at each stage. If the parity error persists, one of the apparatus, and the subsystem corresponding to the affected silicon memory device is reset during a maintenance window.Type: GrantFiled: July 11, 2005Date of Patent: November 11, 2008Assignee: Alcatel LucentInventors: Toby James Koktan, Robert Morton, David Henry Graham, James Wisener, David Motz, Saida Benlarbi, David Ambrose Stortz
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Publication number: 20070172899Abstract: Methods for separating, in a continuous, multizone fluid medium, cells, particles, or other molecules of interest (MOI) from associated or contaminating unwanted materials not of interest (MNOI). The invention involves forced movement of MOI into certain zones having properties which deter the entry of unwanted materials. Differential movement of MOI and MNOI occurs by active counterforces that move MNOI but not MOI. MOI are tagged with magnetic particles and moved with a magnetic field through a fluid, or zones, of higher specific gravity that prevents, by flotation counterforce, unwanted less dense materials from entering. Surfaces specifically coated with reactants are reactive with the MOI in the tagged magnetic particle complex and of buoyant or other forces are used to remove any unbound material from the surface before reading.Type: ApplicationFiled: March 8, 2007Publication date: July 26, 2007Inventors: Henry Graham, John Gorman, James Rowell
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Publication number: 20070059782Abstract: Magnets and magnetic particle-labeled reagents are used to capture and/or release magnetic particle-tagged entities for immunohematology diagnostic testing purposes, especially tests performed in blood banking. The magnetic tagged entities may be tagged antibodies, tagged blood cells, tagged universal binding partners, especially tagged lectins and tagged Coombs reagent, and other binding agents such as biotin-avidin, Protein A or G, ligands and their receptors and the like. Separation of unbound material from bound material is effected through the use of one or both the magnetic field effect on the magnetic labeled reactants and the density gradients of layers of an assay construct. Constructs such as chromatographic strip lateral flow format, and liquid phase reactions in suitable vessels with end point determinations that do not require centrifugation to detect reacted entities.Type: ApplicationFiled: September 11, 2006Publication date: March 15, 2007Inventors: Henry Graham, John Gorman, James Rowell