Patents by Inventor Henry B. Kopf

Henry B. Kopf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9745333
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: August 29, 2017
    Assignee: SMARTFLOW TECHNOLOGIES, INC.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Publication number: 20150183815
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Application
    Filed: July 31, 2014
    Publication date: July 2, 2015
    Inventors: HENRY B. KOPF, JAMES A. KACMAR
  • Patent number: 8795530
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: August 5, 2014
    Assignee: Smartflow Technologies, Inc.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Publication number: 20120205311
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Application
    Filed: January 21, 2010
    Publication date: August 16, 2012
    Applicant: SMARTFLOW TECHNOLOGIES, INC.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Publication number: 20110309018
    Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.
    Type: Application
    Filed: January 21, 2010
    Publication date: December 22, 2011
    Applicant: SMARTFLOW TECHNOLOGIES, INC.
    Inventors: Henry B. Kopf, James A. Kacmar
  • Patent number: 7544296
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: June 9, 2009
    Assignee: NCSRT, Inc.
    Inventors: Henry B. Kopf, Henry Kopf, III
  • Patent number: 6946075
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: September 20, 2005
    Assignee: NCSRT, Inc.
    Inventor: Henry B. Kopf
  • Patent number: 6875459
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: April 5, 2005
    Inventors: Henry B. Kopf, Henry Kopf, III
  • Patent number: 6852352
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: February 8, 2005
    Inventors: Henry B. Kopf, Henry Kopf, III
  • Patent number: 6827960
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: December 7, 2004
    Inventors: Henry B. Kopf, Henry Kopf, III
  • Publication number: 20040142086
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Application
    Filed: December 29, 2003
    Publication date: July 22, 2004
    Inventors: Henry B. Kopf, Henry Kopf
  • Publication number: 20040142068
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Application
    Filed: December 29, 2003
    Publication date: July 22, 2004
    Inventors: Henry B. Kopf, Henry Kopf
  • Publication number: 20040139864
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Application
    Filed: December 29, 2003
    Publication date: July 22, 2004
    Inventors: Henry B. Kopf, Henry Kopf
  • Publication number: 20030201230
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Application
    Filed: May 23, 2003
    Publication date: October 30, 2003
    Inventor: Henry B. Kopf
  • Patent number: 6596172
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: July 22, 2003
    Inventor: Henry B. Kopf
  • Patent number: 6569340
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: May 27, 2003
    Inventor: Henry B. Kopf
  • Publication number: 20030059512
    Abstract: Apparatus and method for separation of milk and milk products, e.g., involving sequential separation of milk, clostrum, and whey components by cross-flow filtration. The apparatus and method in a preferred aspect employ cross-flow filtration, chromatography and fermentation to separate and fully utilize the components of milk, clostrum, and whey to generate numerous individual components, minimize waste, lower adverse environmental issues and provide enhanced economic benefits to dairy producers. A wide variety of consumer and nutraceutical products can be produced from the fractions and/or sub-fractions of milk products obtained from such separation. The invention further contemplates a methodology for selecting optimum membrane, device, and operating conditions to achieve a desired separation.
    Type: Application
    Filed: September 10, 2001
    Publication date: March 27, 2003
    Inventors: Henry B. Kopf, Henry Kopf
  • Publication number: 20020170859
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost- and time-efficiency.
    Type: Application
    Filed: March 27, 2002
    Publication date: November 21, 2002
    Inventor: Henry B. Kopf
  • Patent number: 6383380
    Abstract: A process and apparatus for purifying one or more target substances from a source liquid, employing one or more cross-flow filter elements, and one or more types of chromatography resins, in combination, to provide purification with advantageous yield, product purity, and cost-and time-efficiency.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: May 7, 2002
    Inventor: Henry B. Kopf
  • Publication number: 20010034058
    Abstract: A culturing system and method particularly useful for producing cellular products such as viral pathogens of cells. It includes a mass transfer culture segment, stacked filter plates to adjust the medium composition, and a product removal and concentration segment. The mass transfer culture segment utilizes changed directional flow of the medium to maximize cell growth and production of product. The stacked filter plates allow addition of sterile fresh medium and removal of growth inhibitory substances.
    Type: Application
    Filed: April 9, 2001
    Publication date: October 25, 2001
    Inventor: Henry B. Kopf