Patents by Inventor Henry C. Caldwell

Henry C. Caldwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing low dose pharmaceutical products
    Patent number: 5976570
    Abstract: A process for making pharmaceutical dosage units containing a therapeutic quantity of one or more low dosage medicinal agent comprising granulating said medicinal agent in an aqueous medium which contains a pharmaceutically acceptable surfactant agent and, optionally, further processing the product of said granulating into a tablet or capsule dosage unit.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: November 2, 1999
    Assignee: Applied Analytical Industries, Inc.
    Inventors: Frank C. Greaves, James Swarbrick, Martin W. Beasley, Andrew W. Suddith, Henry C. Caldwell
  • Oral compositions of H2-antagonists
    Patent number: 5622980
    Abstract: The present invention provides a pharmaceutical composition for the oral administration of an H.sub.2 -antagonist. The composition includes an H.sub.2 -antagonist and a silicate taste-masking agent capable of forming an adsorbate complex with the H.sub.2 -antagonist wherein the complex exhibits a non-bitter taste. The complex inhibits the release of the H.sub.2 -antagonist in the oral cavity.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: April 22, 1997
    Assignee: Applied Analytical Industries, Inc.
    Inventors: Henry C. Caldwell, Ashok J. Desai
  • Oral liquid compositions of non-steroidal anti-inflammatory drugs
    Patent number: 5183829
    Abstract: Pharmaceutically elegant oral compositions of non-steroidal anti-inflammatory drugs or their salts are prepared by adding selected dispersing agents such as a polyvinylpyrrolidone, hydroxypropyl-methylcellulose or hydroxypropylcellulose to the NSAIDs in a medium of polyol-glycol-alcohol. The compositions offer the formation of finely dispersed active ingredients upon dispersion in gastric juice.
    Type: Grant
    Filed: September 27, 1991
    Date of Patent: February 2, 1993
    Assignee: Applied Analytical Industries, Inc.
    Inventor: Henry C. Caldwell
  • Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
    Patent number: 5059626
    Abstract: A one phase, liquid composition for oral administration comprises a NSAID such as an anthranilic acid derivative plus a di- or triglyceride of a medium chain fatty acid edible oil which has the characteristics of a pharmaceutical solvent carrier as known to those skilled in the art. Other pharmaceutical additives may be optionally added. An additional stipulation is that ethanol or other monohydric alcohol solvents should not be present.
    Type: Grant
    Filed: January 30, 1991
    Date of Patent: October 22, 1991
    Assignee: Applied Analytical Industries, Inc.
    Inventors: Moo W. Park, Henry C. Caldwell
  • Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
    Patent number: 5011852
    Abstract: A one phase, liquid composition for oral administration comprises a NSAID such as an indoleacetic acid derivative or a pyrroleacetic acid derivative plus a di- or triglyceride of a medium chain fatty acid edible oil which has the characteristics of a pharmaceutical solvent carrier as known to those skilled in the art. Other pharmaceutical additives may be optionally added. An additional stipulation is that ethanol or other monohydric alcohol solvents should not be present.
    Type: Grant
    Filed: March 6, 1990
    Date of Patent: April 30, 1991
    Assignee: Applied Analytical Industries, Inc.
    Inventors: Moo K. Park, Henry C. Caldwell
  • Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
    Patent number: 4918103
    Abstract: A pharmaceutically elegant, one phase, liquid composition for oral administration comprises a NSAID such as ibuprofen plus a di- or triglyceride of a medium chain fatty acid edible oil which has the characteristics of a pharmaceutical solvent carrier as known to those skilled in the art. Other pharmaceutical additives may be optionally added. An additional stipulation is that ethanol or other monohydric alcohol solvents should not be present.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: April 17, 1990
    Assignee: Formulations Development Labs
    Inventors: Moo K. Park, Henry C. Caldwell
  • Pharmaceutical compositions and methods of inhibiting gastric acid secretion
    Patent number: 3932641
    Abstract: Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering N-aminomethyl heterocyclic thioacetamide compounds.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: January 13, 1976
    Assignee: SmithKline Corporation
    Inventors: Henry C. Caldwell, Bernard Loev
  • N-Aminomethyl heterocyclic thioacetamides
    Patent number: 3931162
    Abstract: N-Aminomethyl heterocyclic thioacetamide compounds are prepared by reacting a heterocyclic thioacetamide with formaldehyde and an amine. The products inhibit gastric acid secretion.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: January 6, 1976
    Assignee: SmithKline Corporation
    Inventors: Henry C. Caldwell, Bernard Loev