Abstract: Systems and methods are provided for predicting cardiotoxicity of molecular parameters of a compound. A computer can provide as input to a machine learning algorithm the molecular parameters of the compound. The molecular parameters can include at least structural information about the compound. The machine learning algorithm can have been trained using respective molecular parameters of compounds known to have cardiotoxicity and of compounds known not to have cardiotoxicity. The computer can receive as output from the machine learning algorithm a representation of the predicted cardiotoxicity of each molecular parameter of at least a subset of the molecular parameters of the compound.

Abstract: Systems and methods are provided for predicting cardiotoxicity of molecular parameters of a compound. A computer can provide as input to a machine learning algorithm the molecular parameters of the compound. The molecular parameters can include at least structural information about the compound. The machine learning algorithm can have been trained using respective molecular parameters of compounds known to have cardiotoxicity and of compounds known not to have cardiotoxicity. The computer can receive as output from the machine learning algorithm a representation of the predicted cardiotoxicity of each molecular parameter of at least a subset of the molecular parameters of the compound.

Abstract: A method of signal processing of data using a computer by generating a symbolic map of the data using at least one wavelet transform, identifying target sequences in the symbolic map; and processing the data with reference to the target sequences to obtain waveform prognostic indicators

Abstract: Subcutaneous injection of gas into a body causes insufflation of a cavity, which is followed by infusion of a fluid into the cavity. The fluid preferably carries an active agent, for example a dissolved gas or solute. The method may include iontophoresis of the cavity to enhance diffusion of the active agent into target tissue. Additional steps may be employed to monitor needle tip location to avoid causing damage to an organ by coming into contact with the needle tip or by injecting a gas into a blood vessel.

Abstract: A series of feed-forward applications are designed to synchronize heart/respiration/muscle and brain to produce a better quality of life endpoint. The applications will be used to treat anxiety, sleep disorders, arrhythmias and enhanced performance during athletic training.