Patents by Inventor Henry E. Pelish

Henry E. Pelish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRPK-TPRKB modulators and uses thereof
    Patent number: 9193989
    Abstract: The present invention provides methods of identifying an agent that modulates PRPK, TPRKB, OSGEP, LAGE3 and its homologs, PRPK/TPRKB complex, and/or KEOPS complex. The present invention also provides compositions of such agents and methods of treating a disease, disorder, or condition associated with PRPK, TPRKB, OSGEP, LAGE3 and its homologs family (CT antigens), PRPK/TPRKB complex, and/or KEOPS complex using such an agent or composition.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: November 24, 2015
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Eun Sun Park, Henry E. Pelish, Astrid S. Clarke, Grace L. Williams, Maria Paola Castaldi, Alexander Arefolov, Jennifer E. Ring, Matthew D. Shair, Randall W. King
  • PRPK-TPRKB MODULATORS AND USES THEREOF
    Publication number: 20110319277
    Abstract: The present invention provides methods of identifying an agent that modulates PRPK, TPRKB, OSGEP, LAGE3 and its homologs, PRPK/TPRKB complex, and/or KEOPS complex. The present invention also provides compositions of such agents and methods of treating a disease, disorder, or condition associated with PRPK, TPRKB, OSGEP, LAGE3 and its homologs family (CT antigens), PRPK/TPRKB complex, and/or KEOPS complex using such an agent or composition.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 29, 2011
    Inventors: Eun Sun Park, Henry E. Pelish, Astrid S. Clarke, Grace L. Williams, Maria Paola Castaldi, Alexander Arefolov, Jennifer E. Ring, Matthew D. Shair, Randall W. King
  • Biomimetic combinatorial synthesis
    Publication number: 20010024798
    Abstract: The present invention provides biomimetic compounds and libraries thereof, as well as methods for their production. In general, the inventive method involves the selection of a desired biological synthetic pathway and mimics that synthetic pathway utilizing modern synthetic tools. The structures formed from this method are preferably generated in fewer than four steps. These scaffold structures can then be functionalized to yield biomimetic compounds and libraries of compounds. In preferred embodiments, biomimetic compounds and libraries are generated from an oxidative phenolic coupling reaction. In other particularly preferred embodiments, the compounds and libraries of compounds are generated from cascade reactions to yield bicyclo [n.3.1] ring systems, medium ring systems, and fused ring systems.
    Type: Application
    Filed: April 19, 2001
    Publication date: September 27, 2001
    Inventors: Matthew D. Shair, Craig W. Lindsley, Henry E. Pelish, Scott M. Sheehan, Brian C. Goess, Mark E. Layton, Lawrence K. Chan, Chuo Chen, Nicholas J. Westwood