Patents by Inventor Henry Halperin

Henry Halperin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11717694
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: August 8, 2023
    Assignee: The Johns Hopkins University
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
  • Publication number: 20220314010
    Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.
    Type: Application
    Filed: November 15, 2021
    Publication date: October 6, 2022
    Applicant: The Johns Hopkins University
    Inventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
  • Patent number: 11350888
    Abstract: Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: June 7, 2022
    Assignees: Siemens Healthcare GmbH, The Johns Hopkins University
    Inventors: Julian Krebs, Hiroshi Ashikaga, Tommaso Mansi, Bin Lou, Katherine Chih-ching Wu, Henry Halperin
  • Patent number: 11185707
    Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: November 30, 2021
    Assignee: The Johns Hopkins University
    Inventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
  • Publication number: 20210290967
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Application
    Filed: June 8, 2021
    Publication date: September 23, 2021
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
  • Patent number: 11052261
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: July 6, 2021
    Assignee: The Johns Hopkins University
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
  • Publication number: 20210059900
    Abstract: The present invention is a method for improving hemodynamics and clinical outcome of patients suffering cardiac arrest and other low-flow states by combination of circumferential constriction and anteroposterior compression decompression of the chest cardiopulmonary resuscitation. Anteroposterior compression decompression may be provided by a piston mechanism attached to a gantry above the patient. Circumferential constriction may be achieved by inflation of pneumatic bladders or shortening of a band. The on-off sequence and relative force of circumferential constriction and anteroposterior compression decompression may be adjusted so as to improve efficacy.
    Type: Application
    Filed: September 14, 2020
    Publication date: March 4, 2021
    Inventors: Henry Halperin, Norman Alan Paradis
  • Publication number: 20210059612
    Abstract: Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.
    Type: Application
    Filed: April 10, 2020
    Publication date: March 4, 2021
    Inventors: Julian Krebs, Hiroshi Ashikaga, Tommaso Mansi, Bin Lou, Katherine Chih-ching Wu, Henry Halperin
  • Publication number: 20200086130
    Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.
    Type: Application
    Filed: December 8, 2017
    Publication date: March 19, 2020
    Applicant: The Johns Hopkins University
    Inventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
  • Patent number: 10532216
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: January 14, 2020
    Assignee: The Johns Hopkins University
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
  • Patent number: 10338173
    Abstract: The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: July 2, 2019
    Assignee: The Johns Hopkins University
    Inventors: Aravindan Kolandaivelu, Henry Halperin
  • Publication number: 20180085594
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 29, 2018
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, Henry Hunter
  • Publication number: 20160091581
    Abstract: The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices.
    Type: Application
    Filed: May 22, 2014
    Publication date: March 31, 2016
    Inventors: Aravindan Kolandaivelu, Henry Halperin
  • Publication number: 20150258344
    Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.
    Type: Application
    Filed: January 23, 2015
    Publication date: September 17, 2015
    Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
  • Patent number: 9101780
    Abstract: An embodiment in accordance with the present invention provides an automatic external defibrillator including an anterior pad designed such that it can be used during an endoscopic or surgical procedure that may generate electromagnetic interference. The anterior pad has a first arm adhered longitudinally along and substantially parallel to a left side of a sternum of the subject and a second arm adhered along a 5th intercostal space of the subject. The device also includes a posterior pad. Both the anterior and posterior pads include electrodes for delivering a shock to the subject. The device can also include a wearable component containing sensing electrodes for measuring heart rhythms and a transmitting them to a monitor. The monitor monitors these heart rhythms and alerts the subject or medical care providers to irregularities in the rhythms.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: August 11, 2015
    Assignee: The Johns Hopkins University
    Inventors: Alan Cheng, Henry Halperin
  • Publication number: 20140088658
    Abstract: An embodiment in accordance with the present invention provides an automatic external defibrillator including an anterior pad designed such that it can be used during an endoscopic or surgical procedure that may generate electromagnetic interference. The anterior pad has a first arm adhered longitudinally along and substantially parallel to a left side of a sternum of the subject and a second arm adhered along a 5th intercostal space of the subject. The device also includes a posterior pad. Both the anterior and posterior pads include electrodes for delivering a shock to the subject. The device can also include a wearable component containing sensing electrodes for measuring heart rhythms and a transmitting them to a monitor. The monitor monitors these heart rhythms and alerts the subject or medical care providers to irregularities in the rhythms.
    Type: Application
    Filed: April 9, 2012
    Publication date: March 27, 2014
    Applicant: The John Hopkins University
    Inventors: Alan Cheng, Henry Halperin
  • Publication number: 20080064971
    Abstract: An ECG signal processing system which removes the CPR-induced artifact from measured ECG signals obtained during the administration of CPR.
    Type: Application
    Filed: November 13, 2007
    Publication date: March 13, 2008
    Inventors: Henry Halperin, Ronald Berger
  • Publication number: 20080058635
    Abstract: A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation.
    Type: Application
    Filed: October 26, 2007
    Publication date: March 6, 2008
    Inventors: Henry Halperin, Ronald Berger, Ergin Atalar, Elliot McVeigh, Albert Lardo, Hugh Calkins, Joao Lima
  • Publication number: 20070288058
    Abstract: A band stop filter is provided for a lead wire of an active implantable medical device (AIMD). The band stop filter includes a capacitor in parallel with an inductor. The parallel capacitor and inductor are placed in series with the implantable lead wire of the AIMD, wherein values of capacitance and inductance are selected such that the band stop filter is resonant at a selected frequency. The Q of the inductor may be relatively maximized and the Q of the capacitor may be relatively minimized to reduce the overall Q of the band stop filter to attenuate current flow through the implantable lead wire along a range of selected frequencies. In a preferred form, the band stop filter is integrated into a TIP and/or RING electrode for the active implantable medical device.
    Type: Application
    Filed: May 1, 2007
    Publication date: December 13, 2007
    Applicant: GREATBATCH LTD.
    Inventors: Henry Halperin, Robert Stevenson
  • Publication number: 20070135739
    Abstract: A chest compressions monitor for measuring the depth of chest compressions achieved during CPR. A displacement detector produces a displacement indicative signal indicative of the displacement of the CPR recipient's chest toward the recipient's spine. A signaling mechanism provides chest compression indication signals directing a chest compression force being applied to the chest and a frequency of such compressions.
    Type: Application
    Filed: February 16, 2007
    Publication date: June 14, 2007
    Applicant: Johns Hopkins University
    Inventors: Henry Halperin, Ronald Berger