Patents by Inventor Henry Halperin
Henry Halperin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250281762Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.Type: ApplicationFiled: May 20, 2025Publication date: September 11, 2025Applicant: The Johns Hopkins UniversityInventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
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Patent number: 12329981Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.Type: GrantFiled: November 15, 2021Date of Patent: June 17, 2025Assignee: The Johns Hopkins UniversityInventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
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Patent number: 11717694Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: GrantFiled: June 8, 2021Date of Patent: August 8, 2023Assignee: The Johns Hopkins UniversityInventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
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Publication number: 20220314010Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.Type: ApplicationFiled: November 15, 2021Publication date: October 6, 2022Applicant: The Johns Hopkins UniversityInventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
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Patent number: 11350888Abstract: Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.Type: GrantFiled: April 10, 2020Date of Patent: June 7, 2022Assignees: Siemens Healthcare GmbH, The Johns Hopkins UniversityInventors: Julian Krebs, Hiroshi Ashikaga, Tommaso Mansi, Bin Lou, Katherine Chih-ching Wu, Henry Halperin
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Patent number: 11185707Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.Type: GrantFiled: December 8, 2017Date of Patent: November 30, 2021Assignee: The Johns Hopkins UniversityInventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
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Publication number: 20210290967Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: ApplicationFiled: June 8, 2021Publication date: September 23, 2021Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
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Patent number: 11052261Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: GrantFiled: November 29, 2017Date of Patent: July 6, 2021Assignee: The Johns Hopkins UniversityInventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
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Publication number: 20210059612Abstract: Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.Type: ApplicationFiled: April 10, 2020Publication date: March 4, 2021Inventors: Julian Krebs, Hiroshi Ashikaga, Tommaso Mansi, Bin Lou, Katherine Chih-ching Wu, Henry Halperin
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Publication number: 20210059900Abstract: The present invention is a method for improving hemodynamics and clinical outcome of patients suffering cardiac arrest and other low-flow states by combination of circumferential constriction and anteroposterior compression decompression of the chest cardiopulmonary resuscitation. Anteroposterior compression decompression may be provided by a piston mechanism attached to a gantry above the patient. Circumferential constriction may be achieved by inflation of pneumatic bladders or shortening of a band. The on-off sequence and relative force of circumferential constriction and anteroposterior compression decompression may be adjusted so as to improve efficacy.Type: ApplicationFiled: September 14, 2020Publication date: March 4, 2021Inventors: Henry Halperin, Norman Alan Paradis
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Publication number: 20200086130Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.Type: ApplicationFiled: December 8, 2017Publication date: March 19, 2020Applicant: The Johns Hopkins UniversityInventors: Henry Halperin, Ehud J. Schmidt, Ronald D. Watkins, Harikrishna Tandri, David Hunter, Leslie Tung, Ronald D. Berger
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Patent number: 10532216Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: GrantFiled: January 23, 2015Date of Patent: January 14, 2020Assignee: The Johns Hopkins UniversityInventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
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Patent number: 10338173Abstract: The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices.Type: GrantFiled: May 22, 2014Date of Patent: July 2, 2019Assignee: The Johns Hopkins UniversityInventors: Aravindan Kolandaivelu, Henry Halperin
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Publication number: 20180085594Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: ApplicationFiled: November 29, 2017Publication date: March 29, 2018Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, Henry Hunter
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Publication number: 20160091581Abstract: The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices.Type: ApplicationFiled: May 22, 2014Publication date: March 31, 2016Inventors: Aravindan Kolandaivelu, Henry Halperin
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Publication number: 20150258344Abstract: The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.Type: ApplicationFiled: January 23, 2015Publication date: September 17, 2015Inventors: Harikrishna Tandri, Ronald David Berger, Seth Weinberg, Leslie Tung, Henry Halperin, David Hunter
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Patent number: 9101780Abstract: An embodiment in accordance with the present invention provides an automatic external defibrillator including an anterior pad designed such that it can be used during an endoscopic or surgical procedure that may generate electromagnetic interference. The anterior pad has a first arm adhered longitudinally along and substantially parallel to a left side of a sternum of the subject and a second arm adhered along a 5th intercostal space of the subject. The device also includes a posterior pad. Both the anterior and posterior pads include electrodes for delivering a shock to the subject. The device can also include a wearable component containing sensing electrodes for measuring heart rhythms and a transmitting them to a monitor. The monitor monitors these heart rhythms and alerts the subject or medical care providers to irregularities in the rhythms.Type: GrantFiled: April 9, 2012Date of Patent: August 11, 2015Assignee: The Johns Hopkins UniversityInventors: Alan Cheng, Henry Halperin
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Publication number: 20140088658Abstract: An embodiment in accordance with the present invention provides an automatic external defibrillator including an anterior pad designed such that it can be used during an endoscopic or surgical procedure that may generate electromagnetic interference. The anterior pad has a first arm adhered longitudinally along and substantially parallel to a left side of a sternum of the subject and a second arm adhered along a 5th intercostal space of the subject. The device also includes a posterior pad. Both the anterior and posterior pads include electrodes for delivering a shock to the subject. The device can also include a wearable component containing sensing electrodes for measuring heart rhythms and a transmitting them to a monitor. The monitor monitors these heart rhythms and alerts the subject or medical care providers to irregularities in the rhythms.Type: ApplicationFiled: April 9, 2012Publication date: March 27, 2014Applicant: The John Hopkins UniversityInventors: Alan Cheng, Henry Halperin
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Publication number: 20080064971Abstract: An ECG signal processing system which removes the CPR-induced artifact from measured ECG signals obtained during the administration of CPR.Type: ApplicationFiled: November 13, 2007Publication date: March 13, 2008Inventors: Henry Halperin, Ronald Berger
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Publication number: 20080058635Abstract: A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation.Type: ApplicationFiled: October 26, 2007Publication date: March 6, 2008Inventors: Henry Halperin, Ronald Berger, Ergin Atalar, Elliot McVeigh, Albert Lardo, Hugh Calkins, Joao Lima