Patents by Inventor Henry Hoppe, IV

Henry Hoppe, IV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and therapeutic compositions for treating cystic fibrosis
    Patent number: 5750571
    Abstract: Methods for treating cystic fibrosis are described. The methods involve the administration of a protein enhancing agent, differentiating agent and/or carboxy-compound to a subject afflicted with cystic fibrosis such that mutant cystic fibrosis transmembrane regulator protein present within cystic fibrosis-associated cells becomes functional. Other aspects described include therapeutic compositions and packaged drugs.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: May 12, 1998
    Assignee: Genzyme Corporation
    Inventors: Seng Hing Cheng, Shaona Lee Fang, Henry Hoppe, IV, Alan Edward Smith
  • Methods and therapeutic compositions for treating cystic fibrosis
    Patent number: 5674898
    Abstract: Methods and compositions for treating Cystic Fibrosis by mobilizing mutant forms of CFTR, which retain at least some functional activity, to the plasma membrane where they can mediate chloride ion transport are disclosed.
    Type: Grant
    Filed: June 7, 1993
    Date of Patent: October 7, 1997
    Assignee: Genzyme Corporation
    Inventors: Seng Hing Cheng, Shaona Lee Fang, Henry Hoppe, IV, Alan Edward Smith
  • Assay for mutagenesis in heterozygous diploid human lymphoblasts
    Patent number: 4302535
    Abstract: An assay is disclosed for determining mutagenic damage caused by the administration of a known or suspected mutagen to diploid human lymphoblastoid cell lines. The gene locus employed for this assay is the gene for thymidine kinase, uridine kinase, or cytidine deaminase. Since human lymphoblastoid cells contain two genes for these enzymes, heterozygotes of human lymphoblastoid cells are used in this assay.
    Type: Grant
    Filed: September 27, 1979
    Date of Patent: November 24, 1981
    Assignee: Massachusetts Institute of Technology
    Inventors: Thomas R. Skopek, Howard L. Liber, Bruce W. Penman, William G. Thilly, Henry Hoppe, IV