Patents by Inventor Henry L. Niman

Henry L. Niman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR PREDICTING EMERGENCE AND EXPANSION OF DRUG RESISTANT STRAINS OF INFLUENZA VIRUS
    Publication number: 20100278861
    Abstract: The instant invention provides methods for determining, predicting and characterizing the genetic variability, emergence and expansion of viruses, in particular, influenza. Accordingly, the invention provides methods for identifying virulent pathogens, genetic mutations within pathogens that are relevant to animal health, and methods and compositions for prophylactic or therapeutic intervention against such pathogens.
    Type: Application
    Filed: January 29, 2010
    Publication date: November 4, 2010
    Inventor: Henry L. NIMAN
  • METHODS AND COMPOSITIONS FOR PREDICTING AND TREATING DRUG RESISTANT STRAINS OF INFLUENZA VIRUS
    Publication number: 20100034852
    Abstract: The instant invention provides methods for determining, predicting and characterizing the genetic variability of viruses, in particular, influenza. Accordingly, the invention provides methods for identifying virulent pathogens, genetic mutations within pathogens that are relevant to animal health, and methods and compositions for prophylactic or therapeutic intervention against such pathogens.
    Type: Application
    Filed: January 24, 2008
    Publication date: February 11, 2010
    Inventor: Henry L. Niman
  • Identifying and predicting influenza variants and uses thereof
    Publication number: 20090232843
    Abstract: The instant invention provides methods for determining, predicting and characterizing the genetic variability of viruses, in particular, influenza. Accordingly, the invention provides methods for identifying virulent pathogens, genetic mutations within pathogens that are relevant to animal health, and methods and compositions for prophylactic or therapeutic intervention against such pathogens.
    Type: Application
    Filed: January 4, 2008
    Publication date: September 17, 2009
    Inventor: Henry L. Niman
  • Protein-induced monoclonal receptors to protein ligands
    Publication number: 20030215894
    Abstract: A method of characterizing a biological sample is provided. The method includes the steps of contacting the sample with at least two receptor molecules to generate a first pattern of reactivity and comparing that pattern to a second reactivity pattern generated by a known sample and indicative of oncogene expression.
    Type: Application
    Filed: January 24, 2003
    Publication date: November 20, 2003
    Applicant: The Scripps Research Institute
    Inventor: Henry L. Niman
  • Process for characterizing a biological sample using patterns of oncogene expression
    Patent number: 6551789
    Abstract: A method of characterizing a biological sample is provided. The method includes the steps of contacting the sample with at least two receptor molecules to generate a first pattern of reactivity and comparing that pattern to a second reactivity pattern generated by a known sample and indicative of oncogene expression.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: April 22, 2003
    Assignee: The Scripps Research Institute
    Inventor: Henry L. Niman
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5985587
    Abstract: Monoclonal receptors raised to immunogenic polypeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are method for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand to a portion of which the polypeptide corresponds in sequence, and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: November 16, 1999
    Assignee: The Scripps Research Institute
    Inventors: Henry L. Niman, Richard A. Lerner
  • Method for characterizing antigenic reactivity of biological sample
    Patent number: 5972629
    Abstract: This invention features methods for characterizing antigenic reactivity of biological samples by contacting a biological sample with two or a plurality of monoclonal receptor molecules raised to an immunogen containing a polypeptide of about 7 to about 40 amino acid residues and comparing the ensuing reaction pattern with a pattern generated with a known biological sample.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: October 26, 1999
    Assignee: The Scripps Research Institute
    Inventor: Henry L. Niman
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5786178
    Abstract: Monoclonal receptors raised to immunogenic polypeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are method for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand to a portion of which the polypeptide corresponds in sequence, and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: July 28, 1998
    Assignee: The Scripps Research Institute
    Inventors: Henry L. Niman, Richard A. Lerner
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5733738
    Abstract: The present invention relates to immunological receptors and ligands, and more particularly to monoclonal receptors raised to peptides whose amino acid residue sequences correspond to sequences of retroviral ligands. The receptors are used to assay body samples from a host to indicate exposure of the host to a carcinogen.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: March 31, 1998
    Assignee: Ligand Pharmaceuticals
    Inventor: Henry L. Niman
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5591587
    Abstract: Monoclonal receptors raised to immunogenic polyeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are method for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand to a portion of which the polypeptide corresponds in sequence, and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: August 23, 1994
    Date of Patent: January 7, 1997
    Assignee: The Scripps Research Institute
    Inventor: Henry L. Niman
  • Monoclonal antibodies to oncoproteins and methods of making monoclonal antibodies
    Patent number: 5563247
    Abstract: Monoclonal receptors raised to immunogenic polypeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are methods for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: October 8, 1996
    Assignee: The Scripps Research Institute
    Inventors: Henry L. Niman, Richard A. Lerner
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5030565
    Abstract: Monoclonal receptors raised to immunogenic polypeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are method for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand to a portion of which the polypeptide corresponds in sequence, and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: February 15, 1985
    Date of Patent: July 9, 1991
    Assignee: Scripps Clinic and Research Foundation
    Inventors: Henry L. Niman, Richard A. Lerner
  • Polypeptide-induced monoclonal receptors to protein ligands
    Patent number: 5015571
    Abstract: Monoclonal receptors raised to immunogenic polypeptides whose amino acid residue sequences correspond to sequences of oncoprotein ligands are disclosed, as are method for the production of those receptors and products and methods that utilize them. The monoclonal receptors bind both to the oncoprotein ligand to a portion of which the polypeptide corresponds in sequence, and to the immunogenic polypeptide to which the receptors were raised.
    Type: Grant
    Filed: April 16, 1987
    Date of Patent: May 14, 1991
    Assignee: Scripps Clinic and Research Foundation
    Inventors: Henry L. Niman, Richard A. Lerner