Patents by Inventor Henry M. Grage

Henry M. Grage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11998573
    Abstract: The invention provides compositions and methods of treatment for Dry Eye Syndrome wherein they do not irritate an eye of a human patient who is in need thereof. In particular the invention provides methylglyoxal and Manuka honey in ratios and grades that relieve symptoms and causes of DES without causing irritation to the affected eye(s).
    Type: Grant
    Filed: May 19, 2022
    Date of Patent: June 4, 2024
    Assignee: Oculiant, LLC
    Inventors: Henry M. Grage, Jr., Ajit Nemi
  • Patent number: 11517019
    Abstract: The invention provides a system for sanitizing fluids such as water and air. In particular, the invention provides a combination of solid chlorhexidine and a polymer matrix, for which effluents are essentially free of leached chlorhexidine. The systems enable rapid disinfecting of fluids, including in line at the point of use, and can be employed for both high volume applications and disposable single-use applications.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: December 6, 2022
    Assignee: About Better Life Experiences, LLC
    Inventors: Henry M. Grage, Arthur S. Freeman
  • Publication number: 20220370512
    Abstract: The invention provides compositions and methods of treatment for Dry Eye Syndrome wherein they do not irritate an eye of a human patient who is in need thereof. In particular the invention provides methylglyoxal and Manuka honey in ratios and grades that relieve symptoms and causes of DES without causing irritation to the affected eye(s).
    Type: Application
    Filed: May 19, 2022
    Publication date: November 24, 2022
    Applicant: Oculiant LLC
    Inventors: Henry M. Grage, JR., Ajit Nemi
  • Patent number: 11484033
    Abstract: The invention provides a system for sanitizing fluids such as water and air. In particular, the invention provides a combination of solid chlorhexidine and a polymer matrix, for which effluents are essentially free of leached chlorhexidine. The systems enable rapid disinfecting of fluids, including in line at the point of use, and can be employed for both high volume applications and disposable single-use applications.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: November 1, 2022
    Assignee: About Better Life Experiences, LLC
    Inventors: Henry M. Grage, Arthur S. Freeman
  • Publication number: 20210307330
    Abstract: The invention provides a system for sanitizing fluids such as water and air. In particular, the invention provides a combination of solid chlorhexidine and a polymer matrix, for which effluents are essentially free of leached chlorhexidine. The systems enable rapid disinfecting of fluids, including in line at the point of use, and can be employed for both high volume applications and disposable single-use applications.
    Type: Application
    Filed: February 9, 2021
    Publication date: October 7, 2021
    Applicant: ABLELIFE BIOTECH, Inc.
    Inventor: Henry M. Grage, JR.
  • Patent number: 8740813
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: June 3, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Patent number: 8696596
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: April 15, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Publication number: 20120289864
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Application
    Filed: July 30, 2012
    Publication date: November 15, 2012
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Publication number: 20110046515
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Application
    Filed: November 3, 2010
    Publication date: February 24, 2011
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Publication number: 20100331731
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle, drive mechanism, kneading or vibration mechanism, optional suction system, and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component for receiving the sample and providing testing or analysis indication or readout for the user. In one configuration, the lancing needle may be withdrawn very slightly from the point of maximum penetration to create an opening in which blood can pool before being suctioned through to device.
    Type: Application
    Filed: July 29, 2010
    Publication date: December 30, 2010
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Patent number: 7841991
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: November 30, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Patent number: 7828749
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: November 9, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Publication number: 20100106058
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Application
    Filed: December 22, 2009
    Publication date: April 29, 2010
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Patent number: 7666150
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: February 23, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Patent number: 6793633
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: September 21, 2004
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Publication number: 20040073140
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Application
    Filed: June 26, 2003
    Publication date: April 15, 2004
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Publication number: 20020082522
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Application
    Filed: November 20, 2001
    Publication date: June 27, 2002
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Publication number: 20020010406
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Application
    Filed: September 21, 2001
    Publication date: January 24, 2002
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage
  • Patent number: 6332871
    Abstract: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle, drive mechanism, kneading or vibration mechanism, optional suction system, and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: December 25, 2001
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Ryszard Radwanski, Henry M. Grage, Michael S. Sanchez
  • Patent number: 6319210
    Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
    Type: Grant
    Filed: June 5, 2000
    Date of Patent: November 20, 2001
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, Jeffrey N. Roe, Henry M. Grage