Patents by Inventor Henry Morrison

Henry Morrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT FORMS AND SOLVATES OF MCI-1 ANTAGONISTS
    Publication number: 20230312602
    Abstract: Disclosed herein are salt and solvate forms of. (1S,3?R,6?R,7?S,8?E,11?S,12?R)-6-chloro-7?-methoxy-11?,12?-dimethyl-3,4-dihydro-2H,15?H-spiro[naphthalene-1,22?-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15?-one 13?,13?-dioxide (AMG 176): such as crystalline salt and solvate forms thereof. Also disclosed are methods of making the salt and solvate forms, and methods of treating diseases and disorders with the salt and solvate forms.
    Type: Application
    Filed: April 5, 2023
    Publication date: October 5, 2023
    Inventors: Henry Morrison, Jason S. Tedrow, Stephan D. Parent, Courtney Johnson, Travis Houston, Melanie Bevill
  • PD-1 Binding Proteins and Methods of Use Thereof
    Publication number: 20230272076
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.
    Type: Application
    Filed: August 1, 2022
    Publication date: August 31, 2023
    Inventors: Brydon Bennett, Philip P. Chamberlain, Kandasamy Hariharan, Pilgrim Jackson, Marilyn Kehry, Roli Khattri, Monica Leung, Lisa Morrison, Jeonghoon Sun, Sanaa Torres, Henry H. Chan
  • SALTS AND CRYSTAL FORMS OF OMECAMTIV MECARBIL
    Publication number: 20230108971
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Application
    Filed: September 2, 2022
    Publication date: April 6, 2023
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Alisa Golightly, Bradley Morgan, Matthew Peterson, Alex Eberlin, Alexander Oblezov
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20230044617
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: September 8, 2022
    Publication date: February 9, 2023
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI
  • Salt of omecamtiv mecarbil and process for preparing salt
    Patent number: 11472773
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: October 18, 2022
    Assignee: CYTOKINETICS, INC.
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C. S. Woo, Bradley Paul Morgan, Alex Muci
  • Salts and crystal forms of omecamtiv mecarbil
    Patent number: 11465969
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: October 11, 2022
    Assignees: CYTOKINETICS, INC., AMGEN INC.
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Ailsa Golightly, Bradley Morgan, Matthew Peterson, Alex Eberlin, Alexander Oblezov
  • HYDRATES OF POLYMORPHS OF 6-(1H-INDAZOL-6-YL)-N-(4-MORPHOLINOPHENYL)-2,3-DIHYDROIMIDAZO[1,2-A]PYRAZIN-8-AMINE BIS-MESYLATE AS SYK INHIBITORS
    Publication number: 20220267338
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula IA: are provided. Also provided are process for making the polymorphs and methods of use thereof.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 25, 2022
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • Hydrates of polymorphs of 6-(1H-indazol-6-YL)-N-(4-morpholinophenyl)-2,3-dihydroimidazo[1,2-A]pyrazin-8-amine bisemsylate as Syk inhibitors
    Patent number: 11384082
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula IA: are provided. Also provided are process for making the polymorphs and methods of use thereof.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: July 12, 2022
    Assignee: Kronos Bio, Inc.
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20220153700
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: September 24, 2021
    Publication date: May 19, 2022
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven M. MENNEN, Jacqueline C.S WOO, Bradley Paul MORGAN, Alex MUCI
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20220064181
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: August 3, 2021
    Publication date: March 3, 2022
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • SALTS AND CRYSTAL FORMS OF OMECAMTIV MECARBIL
    Publication number: 20210221771
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Application
    Filed: August 16, 2019
    Publication date: July 22, 2021
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Ailsa Golightly, Bradley Morgan, Matthew Peterson, Alex Eberlin, Alexander Oblezov
  • PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
    Publication number: 20210024537
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Application
    Filed: July 9, 2020
    Publication date: January 28, 2021
    Inventors: Michael Geier, Luke Humphreys, Norihiro Ikemoto, Sean Liew, Henry Morrison, Mark E. Scott, Vimal Varghese
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20200399221
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: July 2, 2020
    Publication date: December 24, 2020
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C.S. Woo, Bradley Paul Morgan, Alex Muci
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20200331859
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: July 2, 2020
    Publication date: October 22, 2020
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C.S. Woo, Bradley Paul Morgan, Alex Muci
  • POLYMORPHS OF SYK INHIBITORS
    Publication number: 20200277293
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: are provided.
    Type: Application
    Filed: August 10, 2018
    Publication date: September 3, 2020
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF
    Publication number: 20200199147
    Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.
    Type: Application
    Filed: November 20, 2019
    Publication date: June 25, 2020
    Inventors: Michael Geier, Luke Humphreys, Norihiro Ikemoto, Sean Liew, Henry Morrison, Mark E. Scott, Vimal Varghese
  • SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20200148699
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: October 10, 2019
    Publication date: May 14, 2020
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20200079736
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: November 14, 2019
    Publication date: March 12, 2020
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C.S. Woo, Bradley Paul Morgan, Alex Muci
  • N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide
    Patent number: RE48285
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: October 27, 2020
    Assignee: Sierra Oncology, Inc.
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin
  • N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide
    Patent number: RE49445
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: March 7, 2023
    Assignee: Sierra Oncology, Inc.
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin