Patents by Inventor Henry Morrison

Henry Morrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts and crystal forms of omecamtiv mecarbil
    Patent number: 12612366
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Grant
    Filed: January 18, 2024
    Date of Patent: April 28, 2026
    Assignee: AMGEN INC.
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao
  • Salt of omecamtiv mecarbil and process for preparing salt
    Patent number: 12583821
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Grant
    Filed: January 24, 2024
    Date of Patent: March 24, 2026
    Assignee: CYTOKINETICS, INC.
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven M. Mennen, Jacqueline C. S. Woo, Bradley Paul Morgan, Alex Muci
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20250243163
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: December 20, 2024
    Publication date: July 31, 2025
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI
  • Salt forms and solvates of Mcl-1 antagonists
    Patent number: 12351588
    Abstract: Disclosed herein are salt and solvate forms of. (1S,3?R,6?R,7?S,8?E,11?S,12?R)-6-chloro-7?-methoxy-11?,12?-dimethyl-3,4-dihydro-2H,15?H-spiro[naphthalene-1,22?-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15?-one 13?,13?-dioxide (AMG 176): such as crystalline salt and solvate forms thereof. Also disclosed are methods of making the salt and solvate forms, and methods of treating diseases and disorders with the salt and solvate forms.
    Type: Grant
    Filed: April 5, 2023
    Date of Patent: July 8, 2025
    Assignee: AMGEN INC.
    Inventors: Henry Morrison, Jason S. Tedrow, Stephan D. Parent, Courtney Johnson, Travis Houston, Melanie Bevill
  • Salt of omecamtiv mecarbil and process for preparing salt
    Patent number: 12221417
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Grant
    Filed: November 27, 2023
    Date of Patent: February 11, 2025
    Assignee: CYTOKINETICS, INC.
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C. S. Woo
  • Hydrates of polymorphs of 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)-2,3-dihydroimidazo[1,2-a]pyrazin-8-amine bis-mesylate as Syk inhibitors
    Patent number: 12122781
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula IA: are provided. Also provided are process for making the polymorphs and methods of use thereof.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: October 22, 2024
    Assignee: Kronos Bio, Inc.
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20240317687
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: January 24, 2024
    Publication date: September 26, 2024
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven M. MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI (Deceased)
  • SALTS AND CRYSTAL FORMS OF OMECAMTIV MECARBIL
    Publication number: 20240199550
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Application
    Filed: January 18, 2024
    Publication date: June 20, 2024
    Inventors: Henry MORRISON, Sheng CUI, Kyle QUASDORF, Evelyn YANEZ, Bin Peter QUAN, Ron C. KELLY, Sebastien CAILLE, Lingyun XIAO, David PEARSON, Jaclyn RAEBURN, Alisa GOLIGHTLY, Bradley MORGAN, Matthew PETERSON, Alex EBERLIN, Alexander OBLEZOV
  • Salt of omecamtiv mecarbil and process for preparing salt
    Patent number: 11958809
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: April 16, 2024
    Assignee: CYTOKINETICS, INC.
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven M. Mennen, Jacqueline C. S. Woo, Bradley Paul Morgan, Alex Muci
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20240101517
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: November 27, 2023
    Publication date: March 28, 2024
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI (DECEASED)
  • Salts and crystal forms of omecamtiv mecarbil
    Patent number: 11926592
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: March 12, 2024
    Assignee: Amgen Inc.
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Alisa Golightly
  • SALT FORMS AND SOLVATES OF MCI-1 ANTAGONISTS
    Publication number: 20230312602
    Abstract: Disclosed herein are salt and solvate forms of. (1S,3?R,6?R,7?S,8?E,11?S,12?R)-6-chloro-7?-methoxy-11?,12?-dimethyl-3,4-dihydro-2H,15?H-spiro[naphthalene-1,22?-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15?-one 13?,13?-dioxide (AMG 176): such as crystalline salt and solvate forms thereof. Also disclosed are methods of making the salt and solvate forms, and methods of treating diseases and disorders with the salt and solvate forms.
    Type: Application
    Filed: April 5, 2023
    Publication date: October 5, 2023
    Inventors: Henry Morrison, Jason S. Tedrow, Stephan D. Parent, Courtney Johnson, Travis Houston, Melanie Bevill
  • SALTS AND CRYSTAL FORMS OF OMECAMTIV MECARBIL
    Publication number: 20230108971
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Application
    Filed: September 2, 2022
    Publication date: April 6, 2023
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Alisa Golightly, Bradley Morgan, Matthew Peterson, Alex Eberlin, Alexander Oblezov
  • SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT
    Publication number: 20230044617
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: September 8, 2022
    Publication date: February 9, 2023
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI
  • Salt of omecamtiv mecarbil and process for preparing salt
    Patent number: 11472773
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: October 18, 2022
    Assignee: CYTOKINETICS, INC.
    Inventors: Sheng Cui, Henry Morrison, Karthik Nagapudi, Shawn D. Walker, Charles Bernard, Karl Bennett Hansen, Neil Fred Langille, Alan Martin Allgeier, Steven Mennen, Jacqueline C. S. Woo, Bradley Paul Morgan, Alex Muci
  • Salts and crystal forms of omecamtiv mecarbil
    Patent number: 11465969
    Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: October 11, 2022
    Assignees: CYTOKINETICS, INC., AMGEN INC.
    Inventors: Henry Morrison, Sheng Cui, Kyle Quasdorf, Evelyn Yanez, Bin Peter Quan, Ron C. Kelly, Sebastien Caille, Lingyun Xiao, David Pearson, Jaclyn Raeburn, Ailsa Golightly, Bradley Morgan, Matthew Peterson, Alex Eberlin, Alexander Oblezov
  • HYDRATES OF POLYMORPHS OF 6-(1H-INDAZOL-6-YL)-N-(4-MORPHOLINOPHENYL)-2,3-DIHYDROIMIDAZO[1,2-A]PYRAZIN-8-AMINE BIS-MESYLATE AS SYK INHIBITORS
    Publication number: 20220267338
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula IA: are provided. Also provided are process for making the polymorphs and methods of use thereof.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 25, 2022
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • Hydrates of polymorphs of 6-(1H-indazol-6-YL)-N-(4-morpholinophenyl)-2,3-dihydroimidazo[1,2-A]pyrazin-8-amine bisemsylate as Syk inhibitors
    Patent number: 11384082
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula IA: are provided. Also provided are process for making the polymorphs and methods of use thereof.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: July 12, 2022
    Assignee: Kronos Bio, Inc.
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Paul Robert Hartmeier, Jesper Alexis Jernelius, Henry Morrison
  • N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide
    Patent number: RE49445
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: March 7, 2023
    Assignee: Sierra Oncology, Inc.
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin
  • (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide
    Patent number: RE50497
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: July 22, 2025
    Assignee: GlaxoSmithKline LLC
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin