Patents by Inventor Henry N. Ginsberg

Henry N. Ginsberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel stimulation of gene expression and protein synthesis of heat shock protein 72/73 (Hsp 70)
    Publication number: 20020111314
    Abstract: This invention provides a method for increasing the level of heat shock protein in a cell which comprises contacting the cell with an effective amount of N-acetyl-leucyl-leucyl-norleucinal, so as to thereby increase the level of heat shock protein in the cell. This invention further provides a protein characterized by increased levels of the protein in a cell in response to contacting the cell with an effective amount of N-acetyl-leucyl-leucyl-norleucinal. This invention also provides a method for increasing the binding of apoprotein B100 to a heat shock protein in a cell. This invention provides a method of preserving an organ ex vivo, which comprises contacting the organ with an effective amount of N-acetyl-leucyl-leucyl-norleucinal. This invention also provides a method of preserving an organ in vivo, which comprises contacting the organ with an effective amount of N-acetyl-leucyl-leucyl-norleucinal.
    Type: Application
    Filed: April 9, 2002
    Publication date: August 15, 2002
    Applicant: The Trustees of Columbia University
    Inventors: Henry N. Ginsberg, Xujun Wu, Mingyue Zhou
  • Stimulation of gene expression and synthesis of heat shock protein 72/73 (HSP 70)
    Patent number: 5942494
    Abstract: This invention provides a method for increasing the level of heat shock protein in a cell which comprises contacting the cell with an effective amount of N-acetyl-leucyl-leucyl-norleucinal, so as to thereby increase the level of heat shock protein in the cell. This invention further provides a protein characterized by increased levels of the protein in a cell in response to contacting the cell with an effective amount of N-acetyl-leucyl-leucyl-norleucinal. This invention also provides a method for increasing the binding of apoprotein B100 to a heat shock protein in a cell. This invention provides a method of preserving an organ ex vivo, which comprises contacting the organ with an effective amount of N-acetyl-leucyl-leucyl-norleucinal. This invention also provides a method of preserving an organ in vivo, which comprises contacting the organ with an effective amount of N-acetyl-leucyl-leucyl-norleucinal.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: August 24, 1999
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Henry N. Ginsberg, Xujun Wu, Mingyue Zhou