Patents by Inventor Henry Nathan, deceased

Henry Nathan, deceased has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5'-deoxy-5'-(substituted)alkylthioribose compounds and their pharmaceutical compositions
    Patent number: 5563125
    Abstract: The compounds 5'-deoxy-5'-(hydroxyethylthio)adenosine (HETA); 5'-deoxy-5'-(monofluoroethylthio)adenosine (MFETA); 5'-deoxy-5'-(chloroethylthio)adenosine (CETA); 5'-deoxy-5'-(bromoethylthio)adenosine (BETA); 5-deoxy-5-(monofluoroethylthio)ribose (MFETR); 5-deoxy-5-(chloroethylthio)ribose (CETR); 5-deoxy-5-(bromoethylthio)ribose (BETR) and 5-deoxy-5-(hydroxyethylthio)ribose (HETR), are described as well as their uses in treating infections caused by 5'-deoxy-5'-methylthioadenosine (MTA) phosphorylase-containing pathogenic microorganisms; in treating infections caused by 5-deoxy-5-methylthioribose (MTR) kinase-containing pathogenic microorganism; and for treating neoplastic diseases.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: October 8, 1996
    Assignees: Health Research, Inc., Pace University
    Inventors: Janice R. Sufrin, Cyrus J. Bacchi, Carl W. Porter, Henry Nathan, deceased, Arthur J. Spiess, Nigel Yarlett