Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.

Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.

Abstract: A sealing assembly for sealing a bundle of wires includes a first sheet formed of a sealant material, a second sheet disposed above the first sheet, and a third sheet disposed above the second sheet formed of the sealant material. The second sheet includes a thermally conductive material. When the bundle of wires is overlaid on the assembly in a first direction, and the assembly is wrapped in a second direction that is generally perpendicular to the first to thereby surround the wires, the second sheet facilitates enhanced thermal energy distribution of applied heat throughout the assembly to thereby more uniformly melt the sealant material and thereby fill voids between the wires.

Abstract: A sensor apparatus includes a mannequin to emulate a human body part. The mannequin includes a core that emulates flexibility of a substantially inflexible skeletal portion of the body part, and a pliant covering. The pliant covering includes a pliant three-dimensional surface that emulates contours of an epidermis of the body part, and at least one pliant three-dimensional interior portion to emulate resiliency of a pliant portion of the body part. At least one pressure sensor is arranged between the three-dimensional surface and the core to sense pressure applied against the pliant three-dimensional surface.

Abstract: Systems and methods for simulating the insertion of a device via cannulation include an external shell which is at least partially filled with a silicone material, a simulated venous flow path, a simulated arterial flow path, one or more pumps to provide fluid to these flow paths, and a visible atrium in fluid communication with the venous flow path. The venous and arterial flow paths are made of flexible and distensible tubing, which is at least partially embedded within the silicone material in cannulation regions, and which is configured to be pierced to allow for insertion of a device therein. The atrium comprises a translucent front wall to enable, before, during, or after insertion of the device, visible inspection inside of the atrium.

Abstract: A prosthetic torso assembly includes a support structure at least partially in a shape of a human torso, where the support structure is formed by a lattice network of rigid material, and a synthetic skin disposed over the support structure and connected to the support structure. The synthetic skin has a thickness, includes silicone or ballistic gel, and is configured to imitate a human torso.

Abstract: A sealing assembly for sealing a bundle of wires includes a first sheet formed of a sealant material, a second sheet disposed above the first sheet, and a third sheet disposed above the second sheet formed of the sealant material. The second sheet includes a thermally conductive material. When the bundle of wires is overlaid on the assembly in a first direction, and the assembly is wrapped in a second direction that is generally perpendicular to the first to thereby surround the wires, the second sheet facilitates enhanced thermal energy distribution of applied heat throughout the assembly to thereby more uniformly melt the sealant material and thereby fill voids between the wires.

Abstract: A laryngoscope is described. The laryngoscope has a handle, a tube, and a camera. The handle has proximal and distal ends. The tube has a proximal end, a distal end, a length extending between the proximal end and the distal end, and a first longitudinal axis along the length. The proximal end is connected to the proximal end of the handle. The tube has an inner surface defining a lumen internal space along the length. The lumen internal space creating a line of sight along a longitudinal axis through the tube. The camera is positioned on the inner surface of the tube to have a field of view out of the distal end of the tube. The camera has a second longitudinal axis offset from the first longitudinal axis of the tube, such that the line of sight along the first longitudinal axis through the tube is maintained.

Abstract: A sealing assembly for sealing a bundle of wires includes a first sheet formed of a sealant material, a second sheet disposed above the first sheet, and a third sheet disposed above the second sheet formed of the sealant material. The second sheet includes a thermally conductive material. When the bundle of wires is overlaid on the assembly in a first direction, and the assembly is wrapped in a second direction that is generally perpendicular to the first to thereby surround the wires, the second sheet facilitates enhanced thermal energy distribution of applied heat throughout the assembly to thereby more uniformly melt the sealant material and thereby fill voids between the wires.

Abstract: A sensor system includes a vessel and a sensor apparatus. The vessel holds a fluid having a predetermined density and at least partly immerses at least one three-dimensional object having a predetermined buoyancy. The sensor apparatus senses a three-dimensional form of the three-dimensional object while at least partly immersed in the fluid and provides a data model representative of the sensed three-dimensional form at least partly immersed in the fluid. The predetermined density of the fluid renders the three-dimensional object substantially buoyancy-neutral.

Abstract: A sensor apparatus includes a mannequin to emulate a human body part. The mannequin includes a core that emulates flexibility of a substantially inflexible skeletal portion of the body part, and a pliant covering. The pliant covering includes a pliant three-dimensional surface that emulates contours of an epidermis of the body part, and at least one pliant three-dimensional interior portion to emulate resiliency of a pliant portion of the body part. At least one pressure sensor is arranged between the three-dimensional surface and the core to sense pressure applied against the pliant three-dimensional surface.

Abstract: A prosthetic torso assembly includes a support structure at least partially in a shape of a human torso, where the support structure is formed by a lattice network of rigid material, and a synthetic skin disposed over the support structure and connected to the support structure. The synthetic skin has a thickness, includes silicone or ballistic gel, and is configured to imitate a human torso.

Abstract: In one aspect, tensegrity structures or apparatus are described herein comprising rings or hoops. Briefly, a tensegrity structure comprises a plurality of rings spaced apart along a central axis and connected by struts, wherein the struts are coupled to a force actuator assembly via cables, the force actuator assembly residing within a volume defined by the struts. In some embodiments, the tensegrity structure employs three struts for connecting the rings, although any desired number of struts is possible. Moreover, cables can extend from opposing ends of the force actuator assembly to couple with the struts.

Abstract: Analyzing a prosthetic torso with synthetic skin and breast tissue includes monitoring a movement of a prosthetic torso with a sensor, and determining, based on data from the sensor, a viscoelastic characteristic of the prosthetic torso. The movement can include at least one of a jumping motion, a walking motion, or a running motion.

Abstract: Examples described herein emulate a processing architecture using multiple translations of the same source binary. A first translation binary includes compiler optimizations not present in a second translation binary. During runtime, a dispatcher directs control flow of a CPU when branch instructions are reached. Specifically, a dispatcher directs a CPU to execute instructions in the first translation binary, and accesses the second translation binary when an instruction is to a target that is not addressable in the first translation binary. The first and second translation binaries enable a target processing architecture to emulate a source processing architecture without just-in-time compilation or other runtime interpretation.

Abstract: Techniques for replication of a client database to remote devices are described. In one embodiment, an apparatus may comprise a server database management component operative to receive a collection subscription command from a client device at a database synchronization system, the collection subscription command specifying an object collection; and detect a collection change for the object collection; and an update queue management component operative to register the client device for push notification with a collection update queue associated with the object collection; and add a collection update to the collection update queue, the collection update based on the collection change. Other embodiments are described and claimed.

Abstract: Examples described herein emulate a processing architecture using multiple translations of the same source binary. A first translation binary includes compiler optimizations not present in a second translation binary. During runtime, a dispatcher directs control flow of a CPU when branch instructions are reached. Specifically, a dispatcher directs a CPU to execute instructions in the first translation binary, and accesses the second translation binary when an instruction is to a target that is not addressable in the first translation binary. The first and second translation binaries enable a target processing architecture to emulate a source processing architecture without just-in-time compilation or other runtime interpretation.

Abstract: Examples described herein emulate a processing architecture using multiple translations of the same source binary. A first translation binary includes compiler optimizations not present in a second translation binary. During runtime, a dispatcher directs control flow of a CPU when branch instructions are reached. Specifically, a dispatcher directs a CPU to execute instructions in the first translation binary, and accesses the second translation binary when an instruction is to a target that is not addressable in the first translation binary. The first and second translation binaries enable a target processing architecture to emulate a source processing architecture without just-in-time compilation or other runtime interpretation.

Abstract: Systems and methods for simulating the insertion of a device via cannulation include an external shell which is at least partially filled with a silicone material, a simulated venous flow path, a simulated arterial flow path, one or more pumps to provide fluid to these flow paths, and a visible atrium in fluid communication with the venous flow path. The venous and arterial flow paths are made of flexible and distensible tubing, which is at least partially embedded within the silicone material in cannulation regions, and which is configured to be pierced to allow for insertion of a device therein. The atrium comprises a translucent front wall to enable, before, during, or after insertion of the device, visible inspection inside of the atrium.