Patents by Inventor Henry Q. Zhang

Henry Q. Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclobut-3-ene-1,2,-dione inhibitors of polo-like kinases
    Patent number: 7956185
    Abstract: Compounds of formula (I) where X1, C1, and D1 are defined herein, are inhibitors of polo-like kinases. The compounds of formula (I) are useful for treatment of diseases of cellular proliferation, such as, for example, cancer.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: June 7, 2011
    Assignee: Abbott Laboratories
    Inventors: Robert B. Diebold, Stevan W. Djuric, Vincent L. Giranda, Laura A. Hexamer, Nan-Horng Lin, Julie M. Miyashiro, Thomas D. Penning, Magdalena Przytulinska, Thomas J. Sowin, Gerard M. Sullivan, Zhi-Fu Tao, Yunsong Tong, Anil Vasudevan, Le Wang, Keith W. Woods, Zhiren Xia, Henry Q. Zhang
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Patent number: 7528134
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: May 5, 2009
    Assignee: Abbott Laboratories Inc.
    Inventors: Pramila A. Bhatia, Jerome F. Daanen, Ahmed A. Hakeem, Teodozyj Kolasa, Mark A. Matulenko, Kathleen H. Mortell, Meena V. Patel, Andrew O. Stewart, Xueqing Wang, Zhiren Xia, Henry Q. Zhang
  • Tricyclic pyrazole kinase inhibitors
    Patent number: 7468371
    Abstract: Compounds of the present invention are useful for inhibiting protein tyrosine kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: December 23, 2008
    Assignee: Abbott Laboratories Inc.
    Inventors: Lee D. Arnold, Jürgen Dinges, Richard W. Dixon, Stevan W. Djuric, Anna M. Ericsson, Kimba Fischer, Alan F. Gasiecki, Vijaya J. Gracias, James H. Holms, Makoto Takeshita, Michael R. Michaelides, Melanie A. Muckey, Paul Rafferty, Douglas H. Steinman, Carol K. Wada, Zhiren Xia, Irini Akritopoulou-Zanze, Henry Q. Zhang
  • Novel amides that activate soluble guanylate cyclase
    Publication number: 20040121994
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: December 20, 2002
    Publication date: June 24, 2004
    Inventors: Steven N. Anderson, Pramila Bhatia, Teodozyj Kolasa, Masaki Nakane, Meena V. Patel, Jeffrey J. Rohde, Zhiren Xia, Henry Q. Zhang
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20040029887
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: April 29, 2003
    Publication date: February 12, 2004
    Inventors: Pramila A. Bhatia, Jerome F. Daanen, Ahmed A. Hakeem, Teodozyj Kolasa, Mark A. Matulenko, Kathleen H. Mortell, Meena V. Patel, Andrew O. Stewart, Xueqing Wang, Zhiren Xia, Henry Q. Zhang
  • Acetamides and benzamides that are useful in treating sexual dysfunction
    Publication number: 20030229094
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: May 23, 2003
    Publication date: December 11, 2003
    Inventors: Pramila A. Bhatia, Jerome F. Daanen, Ahmed A. Hakeem, Teodozyj Kolasa, Mark A. Matulenko, Kathleen H. Mortell, Meena V. Patel, Andrew O. Stewart, Xueqing Wang, Zhiren Xia, Henry Q. Zhang
  • Potassium channel openers
    Patent number: 6645968
    Abstract: Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: November 11, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Hao Bai, Jorge D. Brioni, William A. Carroll, Murali Gopalakrishnan, Robert J. Gregg, Mark W. Holladay, Peggy P. Huang, John F. Kincaid, Michael E. Kort, Philip R. Kym, John K. Lynch, Arturo Perez-Medrano, Henry Q. Zhang
  • Potassium channel openers
    Patent number: 6593335
    Abstract: Compounds having the formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: July 15, 2003
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Yiyuan Chen, Mark W. Holladay, Michael E. Kort, Philip R. Kym, James P. Sullivan, Rui Tang, Lin Yi, Henry Q. Zhang, Irene Drizin
  • Cyclic and bicyclic diamino histamine-3 receptor antagonists
    Patent number: 6559140
    Abstract: Compounds of formula (I) compounds of formula (II) compounds of formula (III) and compounds of formula (IV) or pharmaceutically acceptable salts thereof are useful as H3 receptor antagonists. Processes to make the compounds and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: May 6, 2003
    Assignee: Abbott Laboratories
    Inventors: Youssef L. Bennani, Lawrence A. Black, Wesley J. Dwight, Ramin Faghih, Robert G. Gentles, Huaqing Liu, Kathleen M. Phelan, Anil Vasudevan, Henry Q. Zhang
  • Tricyclic dihydropyrimidine potassium channel openers
    Patent number: 6538000
    Abstract: Compounds of formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: March 25, 2003
    Assignee: Abbott Laboratories
    Inventors: Mark W. Holladay, William A. Carroll, Irene Drizin, Lin Yi, Henry Q. Zhang
  • Potassium channel openers
    Publication number: 20020028836
    Abstract: Compounds of formula I: 1
    Type: Application
    Filed: February 5, 2001
    Publication date: March 7, 2002
    Inventors: Robert J. Altenbach, Hao Bai, Jorge D. Brioni, William A. Carroll, Murali Gopalakrishnan, Robert J. Gregg, Mark W. Holladay, Peggy P. Huang, John F. Kincaid, Michael E. Kort, Philip R. Kym, John K. Lynch, Arturo Perez-Medrano, Henry Q. Zhang
  • Cyclic and bicyclic diamino histamine-3 receptor antagonists
    Publication number: 20010049367
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: March 5, 2001
    Publication date: December 6, 2001
    Inventors: Youssef L. Bennani, Lawrence A. Black, Wesley J. Dwight, Ramin Faghih, Robert G. Gentles, Huaqing Liu, Kathleen M. Phelan, Anil Vasudevan, Henry Q. Zhang
  • Potassium channel openers
    Publication number: 20010036950
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: May 25, 2001
    Publication date: November 1, 2001
    Inventors: William A. Carroll, Irene Drizin, Mark W. Holladay, James P. Sullivan, Henry Q. Zhang
  • Inhibition of nitric oxide synthase by amino acids and dipeptides
    Patent number: 6274557
    Abstract: Methods and compositions for inhibiting at least one isoform of nitric oxide synthase are provided. Pharmaceutical compositions include derivatives of arginine as well as dipeptides and dipeptide analogs that contain nitroarginine or another unnatural amino acid. Compositions can be used to selectively inhibit particular isoforms of nitric oxide synthase.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: August 14, 2001
    Assignee: Northwestern University
    Inventors: Richard B. Silverman, Hui Huang, Henry Q. Zhang
  • Tricyclic dihydropyrimidine potassium channel openers
    Patent number: 6274587
    Abstract: Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: August 14, 2001
    Assignee: Abbott Laboratories
    Inventors: Mark W. Holladay, William A. Carroll, Irene Drizin, Lin Yi, Henry Q. Zhang
  • Potassium channel openers
    Patent number: 6265417
    Abstract: Compounds having the formula are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: July 24, 2001
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Irene Drizin, Mark W. Holladay, James P. Sullivan, Henry Q. Zhang