Patents by Inventor Henry R. Wolfe

Henry R. Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230203088
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Application
    Filed: July 29, 2022
    Publication date: June 29, 2023
    Applicant: DepYmed Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Patent number: 11434257
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: September 6, 2022
    Assignee: DepYmed Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Publication number: 20210128665
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: December 30, 2020
    Publication date: May 6, 2021
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, JR.
  • Publication number: 20200270300
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Application
    Filed: January 30, 2020
    Publication date: August 27, 2020
    Applicant: Ohr Pharmaceutical, Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Publication number: 20200054707
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe
  • Patent number: 10556923
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: February 11, 2020
    Assignee: Ohr Pharmaceutical Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Patent number: 10471115
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: November 12, 2019
    Assignee: KIDNEY STONE RESEARCH COMPANY, INC.
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Publication number: 20190202858
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 4, 2019
    Applicant: Ohr Pharmaceutical, Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Publication number: 20180008660
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 11, 2018
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Patent number: 9789152
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: October 17, 2017
    Assignee: KIDNEY STONE RESEARCH COMPANY, INC.
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Publication number: 20170216388
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: April 14, 2017
    Publication date: August 3, 2017
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, JR.
  • Publication number: 20170129914
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Application
    Filed: October 6, 2016
    Publication date: May 11, 2017
    Applicant: Ohr Pharmaceutical, Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Patent number: 9623066
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: April 18, 2017
    Assignee: KIDNEY STONE LABORATORIES, INC.
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Publication number: 20170065658
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: September 15, 2016
    Publication date: March 9, 2017
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, JR.
  • Publication number: 20170065657
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Application
    Filed: December 7, 2015
    Publication date: March 9, 2017
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, JR.
  • Patent number: 9546194
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: January 17, 2017
    Assignee: Ohr Pharmaceutical, Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Patent number: 9492491
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients combinations of citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: November 15, 2016
    Assignee: KIDNEY STONE LABORATORIES, INC.
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Patent number: 9233135
    Abstract: An oral dosage form or plurality of oral dosage forms comprising as active ingredients citric acid, magnesium citrate, phytin, pyridoxine, and musa is disclosed. The oral dosage form(s) is useful for inhibiting calcium oxalate crystal growth and for treating or inhibiting growth of kidney stones. Methods of inhibiting calcium oxalate crystal growth and of treating or preventing kidney stones are also disclosed.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: January 12, 2016
    Assignee: KIDNEY STONE LABORATORIES, INC.
    Inventors: Gregory K. Hayer, Brendan Magrab, Henry R. Wolfe, Jr.
  • Publication number: 20150099727
    Abstract: This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
    Type: Application
    Filed: April 19, 2013
    Publication date: April 9, 2015
    Applicant: Ohr Pharmaceutical Inc.
    Inventors: Michael McLane, Inez Ruiz-White, W. Lee Maloy, Henry R. Wolfe
  • Patent number: 8206704
    Abstract: Proliferation of colorectal, gastric and esophageal cancer cells is inhibited by administering ST receptor ligand. The number of ST receptor molecules on the surface of a colorectal cell or metastasized colorectal cancer cell are increased by administering an ST receptor ligand such that ligand comes into contact with an ST receptor on the surface of the colorectal cell. Pharmaceutical compositions comprise sterile, pyrogen free ST receptor ligand and a pharmaceutically acceptable carrier or diluent. Metastasized colorectal cancer is treated or imaged by increasing the number of ST receptor molecules on the surface of a metastasized colorectal cancer cell and then administering a pharmaceutical composition containing components that target the ST receptor for delivery of a therapeutic agent or imaging agent. Methods of detecting metastasized colorectal cancer are disclosed. Methods of delivering active compounds to a colorectal cell in an individual are disclosed.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: June 26, 2012
    Assignee: Thomas Jefferson University
    Inventors: Scott A. Waldman, Giovanni Mario Pitari, Jason Park, Stephanie Schulz, Henry R. Wolfe, Wilhelm Lubbe