Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A database is accessed to retrieve performance data associated with a content delivery network. Based on the performance data, a performance metric is determined for components of the content delivery network that are within a particular geographic region. A display is generated that visually represents geographic data representing the particular geographic region, at least one component of the content delivery network within the particular geographic region, and the performance metric.

Abstract: A database is accessed to retrieve performance data associated with a content delivery network. Based on the performance data, a performance metric is determined for components of the content delivery network that are within a particular geographic region. A display is generated that visually represents geographic data representing the particular geographic region, at least one component of the content delivery network within the particular geographic region, and the performance metric.

Abstract: A database is accessed to retrieve performance data associated with a content delivery network. Based on the performance data, a performance metric is determined for components of the content delivery network that are within a particular geographic region. A display is generated that visually represents geographic data representing the particular geographic region, at least one component of the content delivery network within the particular geographic region, and the performance metric.

Abstract: A database is accessed to retrieve performance data associated with a content delivery network. Based on the performance data, a performance metric is determined for components of the content delivery network that are within a particular geographic region. A display is generated that visually represents geographic data representing the particular geographic region, at least one component of the content delivery network within the particular geographic region, and the performance metric.

Abstract: A processor may detect an occurrence of a network anomaly from a set of network operational data collected for a portion of a communication network within a geographic area, detect an occurrence of a weather event from a set of weather data for the geographic area, and determine an occurrence of a weather-related network impairment when the occurrence of the network anomaly and the occurrence of the weather event are detected within a time period, and when the network anomaly and the weather event match a signature for the weather-related network impairment. The processor may further receive, within a time window associated with the time period, a fault report associated with a customer premises within the geographic area and provide a notification and an instruction set to resolve the weather-related network impairment, where the instruction set is stored in a solution record associated with the signature.

Abstract: A processor may detect an occurrence of a network anomaly from a set of network operational data collected for a portion of a communication network within a geographic area, detect an occurrence of a weather event from a set of weather data for the geographic area, and determine an occurrence of a weather-related network impairment when the occurrence of the network anomaly and the occurrence of the weather event are detected within a time period, and when the network anomaly and the weather event match a signature for the weather-related network impairment. The processor may further receive, within a time window associated with the time period, a fault report associated with a customer premises within the geographic area and provide a notification and an instruction set to resolve the weather-related network impairment, where the instruction set is stored in a solution record associated with the signature.

Abstract: A method includes accessing a database to retrieve performance data associated with a content delivery network. The method includes determining, based on the performance data, a performance metric for components of the content delivery network that are within a particular geographic region. The method further includes generating a display that visually represents geographic data representing the particular geographic region, at least one component of the content delivery network within the particular geographic region, and the performance metric.