Abstract: This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.

Abstract: This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.

Abstract: This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.

Abstract: A power supply system for providing power to a device includes a power supply separate from the device, a power supply communication module attached to the power supply, and a device communication module attached to the device. The device communication module communicates voltage and/or current requirements of the device to the power supply via the power supply communication module. A power line is included between the power supply and the device. A communication line may be included between the device communication module and the power supply communication module and/or the device communication module communicates wirelessly with the power supply communication module. The communication line may be separate from the power line or part of the power line. The power line has one end that is attachable to the device.

Abstract: An apparatus for removing particles from air, including an inlet for receiving a flow of air, a first chamber in flow communication with the inlet, wherein a charged spray of semi-conducting fluid droplets having a first polarity is introduced to the air flow so that the particles are electrostatically attracted to and retained by the spray droplets, and an outlet in flow communication with the first chamber, wherein the air flow exits the apparatus substantially free of the particles. The first chamber of the apparatus further includes a collecting surface for attracting the spray droplets, a power supply, and a spray nozzle connected to the power supply for receiving fluid and producing the spray droplets therefrom. The apparatus may also include a second chamber in flow communication with the inlet at a first end and the first chamber at a second end, wherein particles entrained in the air flow are charged with a second polarity opposite the first polarity prior to the air flow entering the first chamber.

Abstract: The present invention provides a reverse flow cyclone separator including a container closed at one end, a component for introducing a fluid mixture swirling about an-axis at a region of the container remote from said end, a barrier between said region and said end, the barrier having a surface facing the introducing component and extending towards the outer wall of the container leaving a gap therebetween, and an outlet for lighter phases of the mixture, the outlet opening from the region, the barrier having an outer perimeter which extends in the axial direction a distance not less than the radial extent of the gap. Since the outlet opens from the region, the flow of fluid from the fluid introducing component to the outlet is not obstructed by the barrier and does not pass through the gap.

Abstract: An apparatus for removing particles from air, including an inlet for receiving a flow of air, a first chamber in flow communication with the inlet, wherein a charged spray of semi-conducting fluid droplets having a first polarity is introduced to the air flow so that the particles are electrostatically attracted to and retained by the spray droplets, and an outlet in flow communication with the first chamber, wherein the air flow exits the apparatus substantially free of the particles. The first chamber of the apparatus further includes a collecting surface for attracting the spray droplets, a power supply, and a spray nozzle connected to the power supply for receiving fluid and producing the spray droplets therefrom. The apparatus may also include a second chamber in flow communication with the inlet at a first end and the first chamber at a second end, wherein particles entrained in the air flow are charged with a second polarity opposite the first polarity prior to the air flow entering the first chamber.

Abstract: A cyclone separator has an inlet chamber 52 and an outlet chamber 53, means 51 for introducing a fluid mixture into the inlet chamber so that it swirls around the chamber and passes to the outlet chamber in which it swirls about an outlet chamber axis, the outlet chamber being provided with means 62 for conducting heavier phase fluids from the outlet chamber at a relatively large distance from the outlet chamber axis and an outlet 63 for lighter phase fluids at a relatively small distance from the outlet chamber axis 55. The flow through the separator and the efficiency of separation are improved by forming at least one of the chambers 52, 53 as involute shaped, the corresponding one 51, 62 of said means being defined by the curved wall of the involute of maximum radius.