Patents by Inventor Henry Wang

Henry Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200377849
    Abstract: The invention relates to a method of culturing mammalian cells expressing a heterologous protein in a perfusion cell culture comprising increasing the potassium concentration and decreasing the molar ratio of sodium to potassium to reduce wasteful cell bleed and to increase protein production. The invention further relates to a serum-free perfusion medium comprising a high potassium ion concentration and a low molar ratio of sodium to potassium and to the use of this medium for use in culturing cells in a perfusion culture during production phase or for reducing the cell bleed volume during production phase.
    Type: Application
    Filed: March 27, 2018
    Publication date: December 3, 2020
    Inventors: Samantha WANG, Henry LIN
  • Patent number: 10854013
    Abstract: Described herein are systems and methods for presenting building information. In overview, the technologies described herein provide relationships between Building Information Modeling (BIM) data (which includes building schematics defined in terms of standardized three dimensional models) and Building Management System (BMS) data (which includes data indicative of the operation of building components such as HVAC components and the like). Some embodiments use relationships between these forms of data thereby to assist technicians in identifying the physical location of particular pieces of equipment, for example in the context of performing inspections and/or maintenance. In some cases this includes the provision of 2D and/or 3D maps to portable devices, these maps including the location of equipment defined both in BIM and BMS data. In some cases, augmented reality technology is applied thereby to provide richer access to positional information.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: December 1, 2020
    Assignee: Honeywell International Inc.
    Inventors: Shailesh Rasane, Ben Coleman, Rajesh Sankarapandian, Kirupakar Janakiraman, Parthasarathy Chinnachamy, Naga Sundar, Sarath Sasidharan, Henry Chen, Xiaoli Wang, Conrad Bruce Beaulieu, Thirumal Raman, Sekar Mookan, Venu Gadde
  • Patent number: 10854129
    Abstract: Hybrid architectures and method methods of operating a display panel are described. In an embodiment, row driver and pixel driver functions are combined in a group of backbone hybrid pixel driver chips, wherein global signal lines are distributed to the backbone hybrid pixel driver chips, where the global signals are manipulated and distributed to a row of pixel driver chips.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: December 1, 2020
    Assignee: Apple Inc.
    Inventors: Xiang Lu, Mahdi Farrokh Baroughi, Xiaofeng Wang, Derek K. Shaeffer, Henry C. Jen, Hopil Bae
  • Patent number: 10815225
    Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: October 27, 2020
    Assignees: MERCK PATENT GMBH, VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Henry Yu, Michael Clark, Guy Bemis, Michael Boyd, Kishan Chandupatla, Philip Collier, Hongbo Deng, Huijun Dong, Warren Dorsch, Russell R. Hoover, Mac Arthur Johnson, Jr., Shashank Kukarni, Marina Penney, Steven Ronkin, Darin Takemoto, Qing Tang, Nathan D. Waal, Tiansheng Wang, David J. Lauffer, Pan Li
  • Publication number: 20200332251
    Abstract: The present disclosure provides a method of culturing mammalian cells, e.g., by perfusion cell culture, expressing a heterologous protein in a cell culture, comprising culturing mammalian cells expressing a heterologous protein in a culture medium comprising an effective amount of one or more lipids or lipid metabolites selected from the group consisting of: linoleic acid, arachidonic acid, and prostaglandin E2, or derivatives and/or precursors thereof. The lipids or lipid metabolites or combinations thereof can lead to growth suppression and/or increased productivity with reduced cell bleed. The present disclosure also provides methods for increasing the productivity of a cell culture by culturing the cells in a culture medium comprising an effective amount of one or more lipids or lipid metabolites selected from the group consisting of: linoleic acid, arachidonic acid, and prostaglandin E2, or derivatives and/or precursors thereof.
    Type: Application
    Filed: October 10, 2018
    Publication date: October 22, 2020
    Inventors: Henry LIN, Samantha WANG, Lili ZHENG
  • Patent number: 10796381
    Abstract: Systems, methods and articles of manufacture for determining impact correlations from a calculation graph for calculating taxes. The system includes a computing device, a data store in communication with the computing device and a tax preparation software application executable by the computing device. The tax preparation software application has a tax calculation engine, a tax calculation graph, and an impact chain engine. The tax calculation engine is configured to perform a plurality of tax calculation operations based on the tax calculation graph. The impact chain engine is configured to analyze the tax calculation graph and determine an impact correlation between a change in a value of a first node caused by a change in a value of a second node utilizing an impact chain which includes both the first node and the second node.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: October 6, 2020
    Assignee: INTUIT INC.
    Inventors: Gang Wang, Kevin M. McCluskey, David A. Hanekamp, Jr., Luis F. Cabrera, Daniel Dunbar, Michael A. Artamonov, Henry Tayloe Stansbury
  • Publication number: 20200307863
    Abstract: A dispenser (1) for liquids includes a reservoir (100) defining a volume (V100) for housing a liquid (150); a delivery tube (200) with a first end (201) attached to the reservoir, and a second end (202) distal from the reservoir, the delivery tube including a passage (203) in fluid communication with the volume of the reservoir and extending away from the reservoir; an applicator element (300) including an applicator tip (320) and a base (310) attached to the second end of the delivery tube, the applicator tip having a plurality of fingers (322) extending away from the base to a distal end of the applicator element distal from the delivery tube; and a removable seal (340), wherein removal of the removable seal creates an opening in the passage at a location upstream of the applicator tip and a fluid distribution channel between the fingers.
    Type: Application
    Filed: November 1, 2018
    Publication date: October 1, 2020
    Inventors: Henry C. Gydesen, Paul R. Klaiber, Yizhong Wang, Bruce R. Broyles
  • Publication number: 20200302871
    Abstract: An electronic device includes a display having an active array and a reference array. The active array includes a pixel and the reference array includes a reference pixel. The electronic device also includes processing circuitry communicatively coupled to the display. The processing circuitry is configured to instruct the active array to drive the pixel based at least in part on a set of degradation ratios and gamma tap points for each brightness setting of the display based at least in part on a reconstructed current-voltage curve.
    Type: Application
    Filed: June 4, 2020
    Publication date: September 24, 2020
    Inventors: Sheng Zhang, Chih-Wei Yeh, Yunhui Hou, Chaohao Wang, Wei H. Yao, Paolo Sacchetto, Derek K. Shaeffer, Henry C. Jen, Shingo Hatanaka, Hasan Akyol, Mahdi Farrokh Baroughi, Hopil Bae
  • Publication number: 20200277403
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Application
    Filed: September 14, 2017
    Publication date: September 3, 2020
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew TSOURKAS, Burcin ALTUN, Hejia Henry WANG, Feifan YU
  • Patent number: 10762836
    Abstract: An electronic display row drivers or column drivers that send reference currents or voltages to microdrivers to be used to drive micropixels to particular levels. The microdrivers, in turn, ship current to micropixels that display images based at least in part on the shipped current.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: September 1, 2020
    Assignee: Apple Inc.
    Inventors: Hopil Bae, Wei H. Yao, Mohammad B. Vahid Far, Yafei Bi, Xiaofeng Wang, Thomas Charisoulis, Hasan Akyol, Henry C. Jen, Derek K. Shaeffer
  • Publication number: 20200261421
    Abstract: The present invention is directed to compounds of Formula I, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
    Type: Application
    Filed: December 19, 2017
    Publication date: August 20, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Brian McKittrick, John P. Caldwell, John A. McCauley, Henry Vaccaro, Tin-Yau Chan, Hyunjin Kim, Elizabeth Smith, Liwu Hong, Tanweer Khan, Shihong Ying, Hongwu Wang
  • Patent number: 10714011
    Abstract: A mobile electronic device includes a display having an active array and a reference array. The active array includes a pixel and the reference array includes a reference pixel. The mobile electronic device also includes processing circuitry communicatively coupled to the display. The processing circuitry is configured to instruct the active array to drive the pixel based at least in part on a current-voltage relationship of the pixel and a reference current-voltage relationship of the reference pixel.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: July 14, 2020
    Assignee: Apple Inc.
    Inventors: Sheng Zhang, Chih-Wei Yeh, Yunhui Hou, Chaohao Wang, Wei H. Yao, Paolo Sacchetto, Derek K. Shaeffer, Henry C. Jen, Shingo Hatanaka, Hasan Akyol, Mahdi Farrokh Baroughi, Hopil Bae
  • Publication number: 20200205775
    Abstract: A needle assembly for use with an autonomous ultrasound imaging system includes a needle having a proximal end and a distal end adapted to be inserted into a patient. The needle assembly also includes a needle transducer mounted to an exterior surface of the needle and is electrically coupled to a power source. The needle transducer is configured to receive data signals from the autonomous ultrasound imaging system which contain information relating to a plurality of ultrasound waves generated by an ultrasound probe of the autonomous ultrasound imaging system.
    Type: Application
    Filed: December 27, 2018
    Publication date: July 2, 2020
    Inventors: Shane A. Duffy, Hakan J. Yazarel, Shirzad Shahriari, Marc Comtois, Tingting Wang, Jamie Collin, Andrew Polijanczuk, Henry Gomersall
  • Publication number: 20200193420
    Abstract: Example data management systems and methods are described. In one implementation, a data management system includes a carbon key configured to store at least one authentication factor associated with a user. The system also includes a hardware wallet configured to communicate with the carbon key. The hardware wallet includes a fingerprint sensor configured to scan a fingerprint of the user, a display configured to receive a personal identification number (PIN) from the user; and a system on chip (SOC) configured to authenticate the carbon key, the fingerprint, and the PIN. Additionally, the SOC can sign a transaction based on authentication of at least two of the carbon key, the fingerprint, and the PIN.
    Type: Application
    Filed: September 4, 2019
    Publication date: June 18, 2020
    Inventors: Henry Michael Vogel, Aleksandar Dukic, Guangda Zhang, Rui Wang
  • Patent number: 10668411
    Abstract: A method of making depth filtration media, such as for use in a depth filter, are described. The resulting depth filtration media includes a core tube having two or more different layers. The layers can be fibers, such as polymeric or inorganic fibers, wrapped layers of a filter material, or pleated and folded layers of a filter material.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: June 2, 2020
    Assignee: Entegris, Inc.
    Inventors: Henry Wang, Dean Tsou, Yi Wei Lu, Bob Shie
  • Patent number: 10666152
    Abstract: A switching power converter is provided with a phase-shifting RC network for phase-shifting a divided version of a drain voltage of a power switch transistor into a phase-shifted voltage. A comparator compares the phase-shifted voltage to a DC bias voltage to detect peaks and valleys during resonant oscillations of the drain voltage of the power switch transistor.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: May 26, 2020
    Assignee: DIALOG SEMICONDUCTOR INC.
    Inventors: Henry Jun, Chuanyang Wang
  • Publication number: 20200148699
    Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.
    Type: Application
    Filed: October 10, 2019
    Publication date: May 14, 2020
    Inventors: Katy Alexander, John C. Amedio, JR., Selcuk Calimsiz, Michael Geier, Geraldine C. Harriman, Sijun Hu, Jon P. Lawson, Henry Morrison, Kyle Sabourin, Mark E. Scott, Vimal Varghese, Kunal Arvind Varia, Xiaotian Wang, Xiaowei Yang
  • Patent number: 10650741
    Abstract: An electronic device includes a display having a reference array that includes a first pixel. The display also includes a first emission power supply coupled to the first pixel. The display further includes an active array having a second pixel. The display also includes a second emission power supply coupled to the second pixel.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: May 12, 2020
    Assignee: Apple Inc.
    Inventors: Sheng Zhang, Chengrui Le, Hopil Bae, Mahdi Farrokh Baroughi, David W. Lum, Adam Adjiwibawa, Chaohao Wang, Paolo Sacchetto, Wei H. Yao, Enkhamgalan Dorjgotov, Michael Slootsky, Giovanni Carbone, Derek K. Shaeffer, Henry C. Jen, Shingo Hatanaka, Hasan Akyol
  • Publication number: 20200122802
    Abstract: Presented here is a system and method for creating easy-to-understand notifications of the vehicle state. The notification can be visual or can be auditory and can indicate to the user the vehicle state even when the user's attention is directed elsewhere. The indication can serve to attract the user's attention before more involved information is presented to the user, such as text, or the indication can serve to communicate to the user the vehicle state in an easy-to-understand way such as using color-coded displays or audio indications. The intensity of the indication can be adjusted based on the likelihood that indication will be perceived by the user by, for example, measuring ambient light and/or ambient noise. Reducing the intensity of the indication conserves energy of an energy source associated with the vehicle.
    Type: Application
    Filed: September 4, 2019
    Publication date: April 23, 2020
    Inventors: Henry W. Bradlow, Hung Yui Lo, Houchang Lu, Yang Song, Meng Xie, Peter Chang, Xiaoxiao Hou, Punit Nitin Shah, Seiwai Wang
  • Patent number: RE48285
    Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: October 27, 2020
    Assignee: Sierra Oncology, Inc.
    Inventors: Brandon H. Brown, Ernest A. Carra, Jeffrey N. Hemenway, Henry Morrison, Troy Reynolds, Bing Shi, Dimitrios Stefanidis, Fang Wang, Matthew Robert Warr, James Andrew Whitney, Yan Xin