Abstract: A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell.

Abstract: A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell.

Abstract: A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell.

Abstract: A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liquid samples are respectively drawn from dissolution vessels, optically-related measurements are taken, and the samples are thereafter returned their respective vessels. The manifold device can be adapted to receive probe-type instruments that incorporate the fiber-optics, wherein each probe-type instrument is associated with each flow cell. Alternatively, each corresponding pair of fiber-optic input and output lines are disposed in opposing, optically-aligned relation and probe-type instruments are not used. The gap between the ends of the opposing fiber-optic lines provides a light path across the corresponding flow cell.

Abstract: For specialized use to secure reliable standardized complete distribution or solution of aggregate mixed into a liquid diluent, a vessel having an interior hemispherical concave bottom having extending upwardly centrally from the concave bottom an arcuate conical member having upright concavely-shaped circumscribing sides. The vessel is taken in conjunction with a stably mounted mixing structure having a downwardly-extending shaft and mixing blades thereof. The shaft on a lower portion thereof supports balanced mixing blades extending radially outwardly from the mixing shaft. The mixing blades are positioned to be substantially spaced below a predetermined liquid level of liquid diluent containing a dissolvable or suspendable aggregate and to be substantially spaced above an upper end of the centrally upwardly arcuate conical member.

Abstract: A combination of a flow-cell with a rate of flow controllable and set to obtain and maintain a solvent or diluent predetermined low flow pressure from the flow-cell's inlet to the flow-cell's outlet, in which at-least an outlet thereof is alternately raised to a height above the inlet thereof sufficiently relative to mass of individual solute(s) and/or individual bead(s) (or other insoluble mass(es)) as to permit the mass of the individual solute(s) and/or individual bead(s) to move by gravity from a direction of the outlet end toward the inlet end of the flow-cell as part of a mechanism ascertainable of improved dissolving of solute and/or suspension of particles of insoluble matter.