Patents by Inventor Heon-Hak Lee

Heon-Hak Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INCREASING PRODUCTIVITY OF 2'-FUCOSYLLACTOSE THROUGH CHANGES IN CULTURE MEDIUM COMPOSITION AND CULTURING
    Publication number: 20240093254
    Abstract: The present invention relates to a method for increasing the productivity of 2?-fucosyllactose through various changes in culture medium composition and culturing on the basis of lactose, which is a substrate, wherein 2-fucosyllactose can be continuously produced in a high-yield at an optimum lactose concentration discovered by a culturing method of the present invention.
    Type: Application
    Filed: October 31, 2022
    Publication date: March 21, 2024
    Applicants: Advanced Protein Technologies Corp., SEOUL NATIONAL UNIVERSITY R&DB FORNDATION
    Inventors: Chul Soo SHIN, Jong Won YOON, Young Ha SONG, Young Sun YOO, Jeong Su BANG, Heon Hak LEE
  • Method for improving productivity of 2?-fucosyllactose through enzymatic treatment
    Patent number: 11753665
    Abstract: Disclosed is a method for improving the productivity of 2?-fucosyllactose (2?-FL) through enzymatic treatment. Lactose used as a substrate in the stationary phase during culture is degraded by treatment with a small amount of enzyme, the resulting glucose is consumed to produce guanosine diphosphate-L-fucose as a precursor of 2?-fucosyllactose, and the use of lactose left after culture can be maximally utilized for the production of 2?-fucosyllactose. As a result, it is possible to increase the productivity of 2?-fucosyllactose in an economically efficient manner because additional glucose is not required while minimizing by-products.
    Type: Grant
    Filed: November 1, 2022
    Date of Patent: September 12, 2023
    Assignees: Advanced Protein Technologies Corp., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Chui Soo Shin, Jong Won Yoon, Young Ha Song, Jong Gil Yoo, Young Sun Yoo, Heon Hak Lee
  • METHOD FOR IMPROVING PRODUCTIVITY OF 2'-FUCOSYLLACTOSE THROUGH ENZYMATIC TREATMENT
    Publication number: 20230193334
    Abstract: Disclosed is a method for improving the productivity of 2?-fucosyllactose (2?-FL) through enzymatic treatment. Lactose used as a substrate in the stationary phase during culture is degraded by treatment with a small amount of enzyme, the resulting glucose is consumed to produce guanosine diphosphate-L-fucose as a precursor of 2?-fucosyllactose, and the use of lactose left after culture can be maximally utilized for the production of 2?-fucosyllactose. As a result, it is possible to increase the productivity of 2?-fucosyllactose in an economically efficient manner because additional glucose is not required while minimizing by-products.
    Type: Application
    Filed: November 1, 2022
    Publication date: June 22, 2023
    Applicant: Advanced Protein Technologies Corp.
    Inventors: Chul Soo SHIN, Jong Won YOON, Young Ha SONG, Jong-GIl YOO, Young Sun Yoo, Heon-Hak Lee