Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative in which sarcosine is substituted with thiosarcosine in the 3-position as an active ingredient.

Abstract: The present invention discloses a topical scalp and transdermal preparation with excellent penetration to the skin and follicle, containing a [?-hydroxy-N-methyl-L-leucine4] cylosporin derivative which is a non-immunosuppressive component with hair growth stimulating ability. The topical scalp and transdermal preparation is prepared by incorporating the cyclosporin derivative into a liposome, microcapsule, micro-sphere, composite particle or emulsion, capable of being employed as a hair growth stimulating agent and applied for the prevention of hair loss.

Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative substituted in the 3-position as an active ingredient.

Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative having an excellent hair growth stimulating ability with little immunosuppressive effect as an active ingredient. In accordance with the invention, there is provided a hair growth promoting agent comprising a cyclosporin derivative represented by Chemical Formula 1 below. The derivatives of the invention were prepared by derivatization of cyclosporins at the amino acid residue 4, N-methyl-L-leucine, and hair growth promoting effects thereof were examined. Such a hair growth promoting agent, comprising a cyclosporin derivative as an active ingredient, exhibits an excellent hair growth effect, while it shows very weak immunosuppressive activity, compared to unmodified cyclosporin A.

Abstract: Disclosed is a hair growth promoting agent including a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent including a cyclosporin A derivative substituted in the 3-position as an active ingredient.

Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative in which sarcosine is substituted with thiosarcosine in the 3-position as an active ingredient.

Abstract: The present invention discloses a composition comprising a cyclosporin derivative having an excellent hair revitalizing activity as an active ingredient, and more particularly, a composition comprising cyclosporin 7-thioamide produced by chemical derivatization of cyclosporin as an active ingredient for promoting hair growth.

Abstract: The present invention discloses a composition comprising a cyclosporin A derivative having an excellent hair revitalizing activity as an active ingredient, and more particularly, a composition comprising cyclosporin A 7-thioamide produced by chemical derivatization of cyclosporin A as an active ingredient for promoting hair growth.

Abstract: Disclosed is a hair growth promoting agent including a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent including a cyclosporin A derivative substituted in the 3-position as an active ingredient.

Abstract: The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative substituted in the 3-position as an active ingredient.

Abstract: The present invention discloses a hair growth promoter comprising [&ggr;-hydroxy-N-methyl-L-leucine9] cyclosporin A, in which a hydroxy group is added to a &ggr; carbon of N-methyl-L-leucine at No. 9 position in cyclosporin A by metabolic action of a microorganism, as an active ingredient.