Patents by Inventor Hepeng SHI

Hepeng SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of compound in preparation of drugs for treating brain glioma
    Patent number: 11400088
    Abstract: The present invention provides uses of a compound represented by formula A in the preparation of drugs for treating brain glioma and particularly glioblastoma. Particularly provided are uses of the compound represented by formula A in the preparation of drugs for treating expression of specific fusion protein. By means of the technical solution of the present invention, typing of brain glioblastoma can be implemented, a drug administration can be carried out for a specific patient group, and precise treatment can be implemented.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: August 2, 2022
    Assignees: BEIJING PEARL BIOTECHNOLOGY LIMITED LIABILITY COMPANY, BEIJING NEUROSURGICAL INSTITUTE
    Inventors: Tao Jiang, Yanwei Liu, Huimin Hu, Hepeng Shi, Weizhe Xue
  • Aminopyrimidine compound, preparation method therefor and use thereof
    Patent number: 11352352
    Abstract: The present invention relates to an aminopyrimidine compound, a preparation method therefor and use thereof. The aminopyrimidine compound has the structure as shown in formula I: the compound is an inhibitor of an epidermal growth factor receptor (EGFR) kinase. The present invention also relates to a pharmaceutical composition containing the compounds, a method for preparing same and the use of same in preparation of anti-tumor drugs.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: June 7, 2022
    Assignee: BEIJING ADAMADLE BIOTECHNOLOGY LIMITED LIABILITY COMPANY
    Inventors: Peilong Zhang, Hepeng Shi, Wenli Lan, Zhitao Song
  • USES OF COMPOUND IN PREPARATION OF DRUGS FOR TREATING BRAIN GLIOMA
    Publication number: 20210369711
    Abstract: The present invention provides uses of a compound represented by formula A in the preparation of drugs for treating brain glioma and particularly glioblastoma. Particularly provided are uses of the compound represented by formula A in the preparation of drugs for treating expression of specific fusion protein. By means of the technical solution of the present invention, typing of brain glioblastoma can be implemented, a drug administration can be carried out for a specific patient group, and precise treatment can be implemented.
    Type: Application
    Filed: December 21, 2016
    Publication date: December 2, 2021
    Inventors: Tao JIANG, Yanwei LIU, Huimin HU, Hepeng SHI, Weizhe XUE
  • AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20200087296
    Abstract: The present invention relates to an aminopyrimidine compound, a preparation method therefor and use thereof. The aminopyrimidine compound has the structure as shown in formula I: the compound is an inhibitor of an epidermal growth factor receptor (EGFR) kinase. The present invention also relates to a pharmaceutical composition containing the compounds, a method for preparing same and the use of same in preparation of anti-tumor drugs.
    Type: Application
    Filed: June 13, 2018
    Publication date: March 19, 2020
    Inventors: Peilong ZHANG, Hepeng SHI, Wenli LAN, Zhitao SONG