Patents by Inventor Heping Yang
Heping Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12159090Abstract: The invention relates to an optimal allocation method for stored energy coordinating electric vehicles (EVs) to participate in auxiliary service market (ASM), including the following steps: 1. Predict the reported capacity of daily 96 points for EVs to participate in the ASM by least square support vector machine (LSSVM). 2. Fit the daily total load distribution of EVs. 3. Determine the error distribution between the reported capacity and the actual response capacity, and simulate the total daily load capacity of EVs in the future with Monte Carlo method. 4. Calculate the energy storage capacity required by EVs daily participating in ASM. 5. Build the objective function to minimize the scheduling risk of auxiliary service. 6. Solve the energy storage model in step 5 with particle swarm optimization (PSO), and output the configuration results of optimal energy storage capacity and energy storage power. The invention can improve the adjustable capacity of EVs participating in ASM.Type: GrantFiled: June 4, 2021Date of Patent: December 3, 2024Assignees: North China Electric Power University, State Grid Electric Vehicle Service Ltd.Inventors: Dunnan Liu, Mingguang Liu, Xiaofeng Peng, Heping Jia, Wen Wang, Lingxiang Wang, Mengjiao Zou, Yue Zhang, Ye Yang, Shu Su, Desheng Bai
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Patent number: 12128512Abstract: An assembly method for a deep in-situ high-fidelity coring calibration platform includes the following steps: S1: fixing a core bin assembly subsystem on a preset ground foundation and fixing a simulator of a core bin on a mounting base plate of the core bin assembly subsystem; S2: driving a cylinder and driving the mounting base plate to move to a preset position; S3: driving a servo motor and controlling two clips to move close to each other; S4: fixing a drill pipe bin assembly subsystem on the ground foundation; S5: assembling multiple sections of a drill pipe bin in turn; aligning and connecting a bottom of the drill pipe bin to the simulator, and aligning and communicating the top of the drill pipe bin with the lower part of an adaptive drill pipe guide structure; and S6: driving the adaptive drill pipe guide structure to perform accurate positioning.Type: GrantFiled: September 23, 2022Date of Patent: October 29, 2024Assignee: SICHUAN UNIVERSITYInventors: Heping Xie, Ru Zhang, Zetian Zhang, Ling Chen, Mingzhong Gao, Zhilong Zhang, Yang Yang, Jianan Li, Wei Huang, Li Ren, Yihang Li, Kun Xiao, Weiqiang Ling, Chendi Lou, Heng Gao
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Patent number: 12090576Abstract: A method for processing a micro-channel of a micro-fluidic chip using multi-focus ultrafast laser, in which an array-type multi-focus femtosecond laser is used to perform fractional ablation on the micro-fluidic chip, and then pulse laser is used to perform secondary ablation on the micro-fluidic chip. Ultrasonic-assisted hydrofluoric acid etching is performed on the micro-fluidic chip after ablation to obtain a true three-dimensional micro-channel on the micro-fluidic chip. A device for processing a micro-channel of a micro-fluidic chip using multi-focus ultrafast laser is also provided.Type: GrantFiled: May 25, 2021Date of Patent: September 17, 2024Inventors: Heping Zeng, Chuan Yang, Mengyun Hu, Shuai Yuan
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Patent number: 12091375Abstract: Disclosed is a preparation method for triphenylchloromethane, comprising the following steps: adding hydrochloric acid or a mixture of hydrochloric acid and Lewis acid to a mixture of triphenylmethanol and an organic solvent; stirring for reaction; removing the water layer after the completion of reaction to obtain an organic solution containing triphenylchloromethane. In the method, the conversion rate of triphenylmethanol is almost quantitative to be above 99%, and the content of triphenylchloromethane in the product obtained is above 99%. The operation is simple, and no waste gas is generated. Therefore, the method is environmentally friendly and suitable for industrialized production and can achieve better economic benefits.Type: GrantFiled: January 6, 2020Date of Patent: September 17, 2024Assignees: Linhai Huanan Chemical Co., Ltd., Zhejiang Huahai Pharmaceutical Co., Ltd.Inventors: Lu Zhang, Guoliang Tu, Jianyue Xu, Heping Jin, Su Wang, Qi Hu, Sen Yang, Heng Liu
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Publication number: 20240299572Abstract: The present application relates to a nitrogen-containing compound, a conjugate containing said compound, and an application thereof. Specifically, the present application provides a compound represented by formula (I), a solvate thereof, a pharmaceutically acceptable salt thereof, or a solvate of a pharmaceutically acceptable salt thereof. The nitrogen-containing compound has a good regulating effect on TLR8 and can effectively treat, alleviate, and/or prevent various diseases caused by immunosuppression, such as a cancer or a viral infection.Type: ApplicationFiled: May 19, 2022Publication date: September 12, 2024Inventors: Zhaolong TONG, Man ZHANG, Heping YANG, Xiaohuan LIU, Longsheng WANG, Jicheng REN, Daxin GAO
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Publication number: 20240261911Abstract: An assembly method for a deep in-situ high-fidelity coring calibration platform includes the following steps: S1: fixing a core bin assembly subsystem on a preset ground foundation and fixing a simulator of a core bin on a mounting base plate of the core bin assembly subsystem; S2: driving a cylinder and driving the mounting base plate to move to a preset position; S3: driving a servo motor and controlling two clips to move close to each other; S4: fixing a drill pipe bin assembly subsystem on the ground foundation; S5: assembling multiple sections of a drill pipe bin in turn; aligning and connecting a bottom of the drill pipe bin to the simulator, and aligning and communicating the top of the drill pipe bin with the lower part of an adaptive drill pipe guide structure; and S6: driving the adaptive drill pipe guide structure to perform accurate positioning.Type: ApplicationFiled: September 23, 2022Publication date: August 8, 2024Applicant: SICHUAN UNIVERSITYInventors: Heping XIE, Ru ZHANG, Zetian ZHANG, Ling CHEN, Mingzhong GAO, Zhilong ZHANG, Yang YANG, Jianan LI, Wei HUANG, Li REN, Yihang LI, Kun XIAO, Weiqiang LING, Chendi LOU, Heng GAO
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Publication number: 20240102042Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.Type: ApplicationFiled: November 8, 2023Publication date: March 28, 2024Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
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Patent number: 11866721Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.Type: GrantFiled: April 9, 2020Date of Patent: January 9, 2024Assignee: MONSANTO TECHNOLOGY LLCInventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
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Publication number: 20230279508Abstract: The invention provides a transgenic corn event ZM_BCS216090, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event ZM_BCS216090. The invention also provides polynucleotides and sequences specific for event ZM_BCS216090 and methods for using plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event ZM_BCS216090 and detecting event ZM_BCS216090, or a polynucleotide or DNA sequence specific for event ZM_BCS216090, in a DNA molecule or sample.Type: ApplicationFiled: October 19, 2022Publication date: September 7, 2023Inventors: Lillian Brzostowski, Carrin Carlson, Kelley Gillespie, Tomasz Paciorek, Lyle Ralston, Alexandar Renaud, Heping Yang
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Patent number: 11587994Abstract: A method for manufacturing the pixel definition layer includes forming a photolithographic material film on a substrate; performing a pre-drying treatment, a first exposure treatment, and a development treatment sequentially on the photolithographic material film to form an initial pattern of the pixel definition layer; and performing a second exposure treatment and a curing treatment sequentially on the initial pattern to form a final pattern of the pixel definition layer.Type: GrantFiled: December 18, 2019Date of Patent: February 21, 2023Assignees: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Shitao Zhang, Li Xiong, Cheng Tang, Hao Zhang, Qijun Zhao, Heping Yang, Gaoliang Xue
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Publication number: 20210367012Abstract: A method for manufacturing the pixel definition layer includes forming a photolithographic material film on a substrate; performing a pre-drying treatment, a first exposure treatment, and a development treatment sequentially on the photolithographic material film to form an initial pattern of the pixel definition layer; and performing a second exposure treatment and a curing treatment sequentially on the initial pattern to form a final pattern of the pixel definition layer.Type: ApplicationFiled: December 18, 2019Publication date: November 25, 2021Inventors: Shitao ZHANG, Li XIONG, Cheng TANG, Hao ZHANG, Qijun ZHAO, Heping YANG, Gaoliang XUE
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Publication number: 20210207162Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).Type: ApplicationFiled: January 12, 2021Publication date: July 8, 2021Inventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
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Patent number: 10920239Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).Type: GrantFiled: January 28, 2019Date of Patent: February 16, 2021Assignee: Monsanto Technology LLCInventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
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Publication number: 20200283790Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.Type: ApplicationFiled: April 9, 2020Publication date: September 10, 2020Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
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Patent number: 10704057Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.Type: GrantFiled: July 14, 2016Date of Patent: July 7, 2020Assignee: Monsanto Technology LLCInventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
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Patent number: 10669252Abstract: Disclosed are a benzazepine derivative, a preparation method, a pharmaceutical composition and the use thereof. A compound as shown in formula (I) of the present invention, and an isomer, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof have the following structure. The benzazepine derivative of the present invention has a good regulation effect on the TLR family and the related signaling pathway, and in particular, has a good regulation effect on TLR8, can effectively treat, relieve and/or prevent various diseases mediated by TLR family and the TLR-related signaling pathway, and in particular, can effectively treat, relieve and/or prevent various diseases mediated by TLR8, such as cancers, autoimmune diseases, infections, inflammations, transplantation rejections, graft-versus-host diseases, etc.Type: GrantFiled: May 4, 2017Date of Patent: June 2, 2020Assignee: SHANGHAI DE NOVO PHARMATECH CO., LTD.Inventors: Daxin Gao, Yuxun Wang, Shoujun Chen, Heping Yang
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Publication number: 20190241903Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).Type: ApplicationFiled: January 28, 2019Publication date: August 8, 2019Inventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
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Publication number: 20190152941Abstract: Disclosed are a benzazepine derivative, a preparation method, a pharmaceutical composition and the use thereof. A compound as shown in formula (I) of the present invention, and an isomer, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof have the following structure. The benzazepine derivative of the present invention has a good regulation effect on the TLR family and the related signaling pathway, and in particular, has a good regulation effect on TLR8, can effectively treat, relieve and/or prevent various diseases mediated by TLR family and the TLR-related signaling pathway, and in particular, can effectively treat, relieve and/or prevent various diseases mediated by TLR8, such as cancers, autoimmune diseases, infections, inflammations, transplantation rejections, graft-versus-host diseases, etc.Type: ApplicationFiled: May 4, 2017Publication date: May 23, 2019Applicant: SHANGHAI DE NOVO PHARMATECH CO., LTD.Inventors: Daxin GAO, Yuxun WANG, Shoujun CHEN, Heping YANG
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Patent number: 9914724Abstract: This invention relates to a kind of C- aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C- aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention relates to a kind of C- aryl glycoside derivatives, it's pharmaceutically acceptable salts or compositions thereof for preparing a SGLT inhibitor. The C- aryl glycoside derivatives of this invention provides a new direction for SGLT inhibitors.Type: GrantFiled: April 1, 2015Date of Patent: March 13, 2018Assignee: SHANGHAI DE NOVO PHARMATECH CO., LTD.Inventors: Daxin Gao, Heping Yang, Pei Wang
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Publication number: 20170037038Abstract: This invention relates to a kind of C-aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C-aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention further relates to a kind of C-aryl glycoside derivatives, it's pharmaceutically acceptable salts or pharmaceutical compositions thereof for the use in preparation of a SGLT inhibitor.Type: ApplicationFiled: April 1, 2015Publication date: February 9, 2017Applicant: SHANGHAI DE NOVO PHARMATECH CO. LTD.Inventors: Daxin GAO, Heping YANG, Pei WANG