Patents by Inventor Heping Yang

Heping Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240102042
    Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 28, 2024
    Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
  • Patent number: 11866721
    Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: January 9, 2024
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
  • Publication number: 20230279508
    Abstract: The invention provides a transgenic corn event ZM_BCS216090, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event ZM_BCS216090. The invention also provides polynucleotides and sequences specific for event ZM_BCS216090 and methods for using plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event ZM_BCS216090 and detecting event ZM_BCS216090, or a polynucleotide or DNA sequence specific for event ZM_BCS216090, in a DNA molecule or sample.
    Type: Application
    Filed: October 19, 2022
    Publication date: September 7, 2023
    Inventors: Lillian Brzostowski, Carrin Carlson, Kelley Gillespie, Tomasz Paciorek, Lyle Ralston, Alexandar Renaud, Heping Yang
  • Patent number: 11587994
    Abstract: A method for manufacturing the pixel definition layer includes forming a photolithographic material film on a substrate; performing a pre-drying treatment, a first exposure treatment, and a development treatment sequentially on the photolithographic material film to form an initial pattern of the pixel definition layer; and performing a second exposure treatment and a curing treatment sequentially on the initial pattern to form a final pattern of the pixel definition layer.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: February 21, 2023
    Assignees: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Shitao Zhang, Li Xiong, Cheng Tang, Hao Zhang, Qijun Zhao, Heping Yang, Gaoliang Xue
  • Publication number: 20210367012
    Abstract: A method for manufacturing the pixel definition layer includes forming a photolithographic material film on a substrate; performing a pre-drying treatment, a first exposure treatment, and a development treatment sequentially on the photolithographic material film to form an initial pattern of the pixel definition layer; and performing a second exposure treatment and a curing treatment sequentially on the initial pattern to form a final pattern of the pixel definition layer.
    Type: Application
    Filed: December 18, 2019
    Publication date: November 25, 2021
    Inventors: Shitao ZHANG, Li XIONG, Cheng TANG, Hao ZHANG, Qijun ZHAO, Heping YANG, Gaoliang XUE
  • Publication number: 20210207162
    Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).
    Type: Application
    Filed: January 12, 2021
    Publication date: July 8, 2021
    Inventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
  • Patent number: 10920239
    Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: February 16, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
  • Publication number: 20200283790
    Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.
    Type: Application
    Filed: April 9, 2020
    Publication date: September 10, 2020
    Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
  • Patent number: 10704057
    Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: July 7, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
  • Patent number: 10669252
    Abstract: Disclosed are a benzazepine derivative, a preparation method, a pharmaceutical composition and the use thereof. A compound as shown in formula (I) of the present invention, and an isomer, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof have the following structure. The benzazepine derivative of the present invention has a good regulation effect on the TLR family and the related signaling pathway, and in particular, has a good regulation effect on TLR8, can effectively treat, relieve and/or prevent various diseases mediated by TLR family and the TLR-related signaling pathway, and in particular, can effectively treat, relieve and/or prevent various diseases mediated by TLR8, such as cancers, autoimmune diseases, infections, inflammations, transplantation rejections, graft-versus-host diseases, etc.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 2, 2020
    Assignee: SHANGHAI DE NOVO PHARMATECH CO., LTD.
    Inventors: Daxin Gao, Yuxun Wang, Shoujun Chen, Heping Yang
  • Publication number: 20190241903
    Abstract: The invention provides recombinant DNA molecules that are unique to maize event MON87429 and transgenic maize plants, maize plant parts, maize seeds, maize cells, and agricultural products containing maize event MON87429 as well as methods of using and detecting maize event MON87429. Transgenic maize plants containing maize event MON87429 exhibit tolerance to inhibitors of acetyl CoA carboxylase (ACCase) in the aryloxyphenoxy propionate (FOP) group, synthetic auxins, inhibitors of glutamine synthetase, and inhibitors of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).
    Type: Application
    Filed: January 28, 2019
    Publication date: August 8, 2019
    Inventors: Christine M. Ellis, Michael E. Goley, Jintai Huang, Tracy E. Klingaman, Clayton T. Larue, Youlin Qi, Oscar C. Sparks, Brook M. Van Scoyoc, Heping Yang
  • Publication number: 20190152941
    Abstract: Disclosed are a benzazepine derivative, a preparation method, a pharmaceutical composition and the use thereof. A compound as shown in formula (I) of the present invention, and an isomer, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof have the following structure. The benzazepine derivative of the present invention has a good regulation effect on the TLR family and the related signaling pathway, and in particular, has a good regulation effect on TLR8, can effectively treat, relieve and/or prevent various diseases mediated by TLR family and the TLR-related signaling pathway, and in particular, can effectively treat, relieve and/or prevent various diseases mediated by TLR8, such as cancers, autoimmune diseases, infections, inflammations, transplantation rejections, graft-versus-host diseases, etc.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 23, 2019
    Applicant: SHANGHAI DE NOVO PHARMATECH CO., LTD.
    Inventors: Daxin GAO, Yuxun WANG, Shoujun CHEN, Heping YANG
  • Patent number: 9914724
    Abstract: This invention relates to a kind of C- aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C- aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention relates to a kind of C- aryl glycoside derivatives, it's pharmaceutically acceptable salts or compositions thereof for preparing a SGLT inhibitor. The C- aryl glycoside derivatives of this invention provides a new direction for SGLT inhibitors.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: March 13, 2018
    Assignee: SHANGHAI DE NOVO PHARMATECH CO., LTD.
    Inventors: Daxin Gao, Heping Yang, Pei Wang
  • Publication number: 20170037038
    Abstract: This invention relates to a kind of C-aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C-aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention further relates to a kind of C-aryl glycoside derivatives, it's pharmaceutically acceptable salts or pharmaceutical compositions thereof for the use in preparation of a SGLT inhibitor.
    Type: Application
    Filed: April 1, 2015
    Publication date: February 9, 2017
    Applicant: SHANGHAI DE NOVO PHARMATECH CO. LTD.
    Inventors: Daxin GAO, Heping YANG, Pei WANG
  • Publication number: 20170029841
    Abstract: The invention provides novel recombinant DNA molecules, compositions, and methods for selectively regulating the expression of a transcribable polynucleotide molecule or recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising such DNA molecules and compositions.
    Type: Application
    Filed: July 14, 2016
    Publication date: February 2, 2017
    Inventors: Jintai Huang, Youlin Qi, Heping Yang, Yuanji Zhang
  • Patent number: 9216997
    Abstract: The present invention relates to a tri-heterocyclic derivatives, preparation process and uses thereof, specifically relates to a tri-heterocyclic derivatives of the formula (I) or a pharmaceutically acceptable salt thereof, preparation process, and further relates to a pharmaceutically acceptable composition comprising compounds of formula (I), or a pharmaceutically acceptable salt thereof, and their pharmaceutical use as inhibitors of kinase.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: December 22, 2015
    Assignee: Shanghai De Novo Pharmatech Co Ltd.
    Inventors: Daxin Gao, Heping Yang, Yajun Yu
  • Publication number: 20140329800
    Abstract: The present invention relates to a tri-heterocyclic derivatives, preparation process and uses thereof, specifically relates to a tri-heterocyclic derivatives of the formula (I) or a pharmaceutically acceptable salt thereof, preparation process, and further relates to a pharmaceutically acceptable composition comprising compounds of formula (I), or a pharmaceutically acceptable salt thereof, and their pharmaceutical use as inhibitors of kinase.
    Type: Application
    Filed: December 13, 2012
    Publication date: November 6, 2014
    Inventors: Daxin Gao, Heping Yang, Yajun Yu
  • Patent number: 8752885
    Abstract: A releasable tunnel brace for releasably connecting a first side panel to a second panel of a vehicle is disclosed. One or both ends of the brace include a fastener-receiving aperture. The aperture has a round portion and an elongated slot extending therefrom. The round portion can allow the head of a shoulder bolt fastener to pass therethrough. The elongated slot is defined by a pair of opposed walls. The shoulder of the shoulder bolt fastener can pass between the opposed walls. In the event of a side impact, the brace is pushed vehicle inward and the bolt slides through the elongated slot and into the round portion where it is allowed to be released from its attachment position. The brace provides maximum torsion stiffness while withstanding only a minimum amount of lateral force before it releases and thus minimizes local deflection in the event of a side impact.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: June 17, 2014
    Assignee: Ford Global Technologies, LLC
    Inventor: Heping Yang
  • Publication number: 20140021745
    Abstract: A releasable tunnel brace for releasably connecting a first side panel to a second panel of a vehicle is disclosed. One or both ends of the brace include a fastener-receiving aperture. The aperture has a round portion and an elongated slot extending therefrom. The round portion can allow the head of a shoulder bolt fastener to pass therethrough. The elongated slot is defined by a pair of opposed walls. The shoulder of the shoulder bolt fastener can pass between the opposed walls. In the event of a side impact, the brace is pushed vehicle inward and the bolt slides through the elongated slot and into the round portion where it is allowed to be released from its attachment position. The brace provides maximum torsion stiffness while withstanding only a minimum amount of lateral force before it releases and thus minimizes local deflection in the event of a side impact.
    Type: Application
    Filed: July 23, 2012
    Publication date: January 23, 2014
    Applicant: FORD GLOBAL TECHNOLOGIES, LLC
    Inventor: Heping Yang
  • Publication number: 20130288895
    Abstract: Provided are novel compositions for use in herbicide activity. Specifically, methods and compositions that modulate 5-enolpyruvylshikimate-3-phosphate synthase in plant species. The present invention also provides for combinations of compositions and methods that enhance weed control.
    Type: Application
    Filed: September 13, 2012
    Publication date: October 31, 2013
    Inventors: Daniel Ader, Zhaolong Li, Ronak Hasmukh Shah, Mengbing Tao, Dafu Wang, Heping Yang