Patents by Inventor Herbert A. Blough

Herbert A. Blough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions of N-(phosphonoacetyl)-L-aspartic acid and methods of their use as broad spectrum antivirals
    Patent number: 5491135
    Abstract: Compositions and methods are disclosed which utilize the broad spectrum antiviral activity of PALA. This compound and its pharmaceutically acceptable analogs possess potent activity while displaying minimal toxicity and, therefore, are characterized by a relatively high therapeutic index. Compositions optionally containing other therapeutic agents, such as other antiviral agents, are also disclosed and are found to possess synergistic and/or additive antiviral activity.
    Type: Grant
    Filed: March 17, 1993
    Date of Patent: February 13, 1996
    Assignee: U.S. Bioscience, Inc.
    Inventor: Herbert A. Blough
  • Antiviral agent against herpes virus infections
    Patent number: 4603122
    Abstract: A method of treating herpes virus infections by the administration of 2-deoxy-D-glucose is described. The sugar analog is effective in treating herpes simplex virus infections such as, genital herpes, labial herpes, and ocular herpes; and other herpes infections such as, herpes zoster, varicella, mononucleosis, erythema multiforme and cytomegalovirus.
    Type: Grant
    Filed: February 3, 1982
    Date of Patent: July 29, 1986
    Inventor: Herbert A. Blough
  • 2-Deoxy glucose as an antiviral agent against herpes simplex
    Patent number: 4315001
    Abstract: A method of treating herpes simplex virus by the administration of 2-deoxy-D-glucose is described. The sugar analog is effective in treating genital herpes, labial herpes, and ocular herpes.
    Type: Grant
    Filed: August 17, 1979
    Date of Patent: February 9, 1982
    Inventor: Herbert A. Blough