Patents by Inventor Herbert B. Winicov

Herbert B. Winicov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines
    Patent number: 5008390
    Abstract: 6-Aryl-2,3-dihydroimidazo[2,1-b]thiazoles and corresponding thiazines act as nucleophiles, either directly or in the form of Grignard reagents, with N-acylpyridinium salts to produce new 6-aryl-5-(N-acyl-1,4-dihydro-4-pyridyl)-2,3-dihydroimidazo-[2,1-b]thiazole s and corresponding thiazines. These are oxidized to give the corresponding pyridyl-substituted imidazo[2,1-b]thiazoles and thiazines, which are active as inhibitors of the 5-lipoxygenase pathway of arachidonic acid metabolism.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 16, 1991
    Assignee: SmithKline Beckman Corporation
    Inventors: Paul E. Bender, Ivan Lantos, Michael A. McGuire, Lendon N. Pridgen, Herbert B. Winicov
  • 1.4-dihydro-4-pyridyl-substituted imidazo (2,1-b) thiazoles and the corresponding thiazines.
    Patent number: 4803279
    Abstract: 6-Aryl-2,3-dihydroimidazo[2,1-b]thiazoles and corresponding thiazines act as nucleophiles, either directly or in the form of Grignard reagents, with N-acylpyridinium salts to produce new 6-aryl-5-(N-acyl-1,4-dihydro-4-pyridyl)-2,3-dihydroimidazo-[2,1-b]thiazole s and corresponding thiazines. These are oxidized to give the corresponding pyridyl-substituted imidazo[2,1-b]thiazoles and thiazines, which are active as inhibitors of the 5-lipoxygenase pathway of arachidonic acid metabolism.
    Type: Grant
    Filed: April 28, 1986
    Date of Patent: February 7, 1989
    Assignee: SmithKline Beckman Corporation
    Inventors: Paul E. Bender, Ivan Lantos, Michael A. McGuire, Lendon N. Pridgen, Herbert B. Winicov