Abstract: A dose delivery mechanism includes a housing, a piston rod to act on a plunger sealing a fluid compartment and to move in an axial direction relative to the housing to deliver a set dose, and a dose setting member movable relative to the housing during dose setting. A position of the dose setting member relative to the housing defines the set dose, and in an as-delivered condition, the dose setting member is preset to a position that corresponds to a set dose higher than zero.

Abstract: A set includes a medicament delivery device with a dose delivery activation mechanism to adjust the medicament delivery device from an inactive state to an active state in which a dose is deliverable, and a cover. The cover is mechanically attached to the medicament delivery device prior to use of the medicament delivery device. The cover covers a part of the dose delivery activation mechanism so that a user is restrained from prematurely activating the medicament delivery device, and the cover is movable in a distal direction to uncover the part of the dose delivery activation mechanism to activate the medicament delivery device during use of the medicament delivery device.

Abstract: A dose delivery mechanism includes a piston rod and a nut, the piston rod forms an outer thread meshing with an inner thread of the nut. During dose setting, the nut rotates relative to the piston rod to advance the nut with respect to the piston rod by a first distance into a distal direction, an actuation member that is movable by a user to effect delivery of a set dose, and a housing. A second threaded connection causes the actuation member to travel a second distance into the distal direction during dose setting. The the actuation member is coupled via the nut to the piston rod during dose delivery to advance the piston rod by the first distance into a proximal direction upon proximal movement of the actuation member by the second distance, and the second distance is less than 1.5 times the first distance.

Abstract: A cartridge holding unit includes a cartridge container forming an outer surface of the cartridge holding unit and having an inner space, and a cartridge holder forming a tube-shaped holding section arranged in the inner space of the cartridge container. The cartridge holder firmly holds a cartridge in parallel with the cartridge holder and the cartridge holder and the cartridge container are firmly coupled to each other in respective axial orientations.

Abstract: A dose delivery mechanism includes a housing, a piston rod, and an adjusting element. The housing connecting to a container sealed by a plunger. In an assembled state, the dose delivery mechanism moves the piston rod axially in a proximal direction during dose delivery such that the piston rod exerts an axial force on the plunger to expel a medicament. In the preassembled state, the adjusting element rotates with respect to the housing, causing axial movement of the piston rod to adjust an axial position of the piston rod prior to transfer of the dose delivery mechanism from the preassembled state into the assembled state. An outer rim of the adjusting element effects rotation of the adjusting element and axial movement of the piston rod. The adjusting element performs rotation at least while being in a preassembled position with respect to the housing.

Abstract: A dose setting mechanism includes a housing, a dose setting knob, and a dose setting device. The dose setting knob sets the desired dose by compulsory guided combined axial and rotational movement of the dose setting knob relative to the housing. The dose setting mechanism includes a coupling element, and upon drug delivery, the dose setting knob moves axially relative to the dose setting device or the housing. The coupling element engages at least one of the dose setting device and the housing to permanently axially lock the dose setting knob to one of the dose setting device or the housing.

Abstract: A dose setting mechanism is provided that includes a dose knob, a dose selector, a radial projecting rib and a snap element. The radial projecting rib is positioned circumferentially on an inside surface of the dose selector. The snap element includes a protrusion. The protruding rib has a reduced section that allows the protruding rib to move axially relative to the protrusion to initiate dose delivery.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a fail safe feature that activates during an interrupted dose delivery event. A dose selector having a projecting rib engages a protrusion on a snap element to prevent the dose knob from moving distally if a user removes an axial force in the proximal direction during dose delivery. The dose setting mechanism can further include a reuse prevention feature.

Abstract: A dose delivery mechanism includes a housing, a piston rod that acts on a plunger sealing a fluid compartment and moves in an axial direction relative to the housing to deliver a set dose, and a dose setting member that is movable relative to the housing during dose setting. A position of the dose setting member relative to the housing defines the set dose, and in an as-delivered condition the dose setting member is preset to a position that corresponds to a set dose higher than zero.

Abstract: A dose setting mechanism is provided that includes a dose knob, a dose selector, a radial projecting rib and a snap element. The radial projecting rib is positioned circumferentially on an inside surface of the dose selector. The snap element includes a protrusion. The protruding rib has a reduced section that allows the protruding rib to move axially relative to the protrusion to initiate dose delivery.

Abstract: A set includes a medicament delivery device with a dose delivery activation mechanism that is configured to adjust the medicament delivery device from an inactive state to an active state in which a dose is deliverable, and a cover. The cover is mechanically attached to the medicament delivery device prior to use of the medicament delivery device, and is configured to cover at least a part of the dose delivery activation mechanism so that a user is restrained from prematurely activating the medicament delivery device. The cover is configured to be movable in a distal direction to uncover the part of the dose delivery activation mechanism to activate the medicament delivery device during use of the medicament delivery device.

Abstract: A dose delivery mechanism includes a piston rod and a nut. The piston rod forms an outer thread meshing with an inner thread of the nut, and during dose setting, the nut is rotated relative to the piston rod to advance the nut with respect to the piston rod by a first distance into a distal direction, an actuation member that is movable by a user to effect delivery of a set dose, and a housing. A second threaded connection is configured to cause the actuation member to travel a second distance into the distal direction during dose setting. The actuation member is coupled via the nut to the piston rod during dose delivery to advance the piston rod by the first distance into a proximal direction upon proximal movement of the actuation member by the second distance, and the second distance is less than 1.5 times the first distance.

Abstract: A dose setting mechanism configured to set a desired dose for an injection device, the dose setting mechanism includes a housing, a dose setting knob, a dose setting device and a coupling element. The dose setting knob is configured to set the desired dose by a compulsory guided combined axial and rotational movement of the dose setting knob relative to the housing. Upon drug delivery, the dose setting knob is moved axially relative to the dose setting device or the housing and the coupling element is configured to engage at least one of the dose setting device and the housing to thereby permanently axially lock the dose setting knob to the respective one of the dose setting device and the housing.

Abstract: A delivery device includes a housing, a controller for setting a dose and a sensor mechanism for recording the dose set by the controller. The controller rotates with respect to the housing around a longitudinal axis and moves axially with respect to the housing along the longitudinal axis during dose setting. The sensor mechanism includes an electronics module and a dose setting sensor with a first sensor element and a second sensor element. The electronics module and the first sensor element are rotationally and axially fixed with respect to the controller and the second sensor element is rotationally fixed with respect to the housing and rotationally movable with respect to the controller. The first and second sensor element are at least temporarily positioned outside of the housing along the longitudinal axis during dose setting.

Abstract: A dose delivery mechanism for a medicament delivery device includes a housing, a piston rod, and an adjusting element. The housing is configured to connect to a medicament container sealed by a plunger. In the assembled state, the dose delivery mechanism is configured to move the piston rod axially in a proximal direction with respect to the housing during dose delivery such that the piston rod exerts an axial force in the proximal direction on the plunger of the medicament container to expel a medicament from the medicament container.

Abstract: A rotary pump is presented for use in a medicament delivery device, where the pump has a back plate having an inner surface and a rotor housing is positioned adjacent to the back plate having a peripheral wall. A front plate support is connected to the back plate and a flexible front plate is positioned between the front plate support and the rotor housing. The pump is rotated using a planetary gear transmission, where an eccentric shaft is operatively connected to the planetary gear mechanism. A rotor is rotationally fixed to the eccentric shaft and movably positioned within the rotor housing. The rotor has three lobes, where each lobe has two peripheral curved surfaces sharing a common apex, where a first portion of each peripheral surface adjacent to the apex defines a non-smooth curve.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a fail safe feature that activates during an interrupted dose delivery event. A dose selector having a projecting rib engages a protrusion on a snap element to prevent the dose knob from moving distally if a user removes an axial force in the proximal direction during dose delivery. The dose setting mechanism can further include a reuse prevention feature.

Abstract: An injection device includes a housing having a receptacle for a vessel for holding injection fluid; an operator-manipulated element for setting an injection dose; a dosing member rotatable about a longitudinal center axis relative to the housing when setting the injection dose; a feed part; and, a latching unit acting between the feed part and housing. The dosing member has a zero position whereat no dose is set and an injection position whereat an intended dose of injection fluid is set. A spring acts between the dosing member and the housing to return the dosing member from an intermediate position to the injection position or a zero position.

Abstract: A rotary pump is presented for use in a medicament delivery device, where the pump has a back plate having an inner surface and a rotor housing is positioned adjacent to the back plate having a peripheral wall. A front plate support is connected to the back plate and a flexible front plate is positioned between the front plate support and the rotor housing. The pump is rotated using a planetary gear transmission, where an eccentric shaft is operatively connected to the planetary gear mechanism. A rotor is rotationally fixed to the eccentric shaft and movably positioned within rotor housing. The rotor has three lobes, where each lobe has two peripheral curved surfaces sharing a common apex, where a first portion of each peripheral surface adjacent to the apex defines a non-smooth curve.