Patents by Inventor Herbert Buschek
Herbert Buschek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8940230Abstract: A cell for conducting electrochemiluminescence measurements is disclosed. The cell in one embodiment provides a measurement cell housing having a cavity, a fluid inlet channel for inducing fluid into the cavity and a fluid outlet channel for discharging fluid from the cavity at axial ends. The cell also provides at least one working electrode and a counter electrode on or in the cavity, and an optical viewing element for observing electrochemiluminescence effects in the cavity, wherein the fluid inlet channel has an at least approximately continuous curved course in a transition area to the cavity so that the fluid inlet channel at its end which is joined to the cavity is shaped in such a manner as to constitute a continuous course of the transition between the fluid inlet channel and the cavity to generate a largely steady flow profile when inducing fluid into the measurement cell cavity.Type: GrantFiled: August 23, 2007Date of Patent: January 27, 2015Assignee: Roche Diagnostics Operations, Inc.Inventors: Michael Kühnl, Herbert Buschek, Reinhold Krämer, Petra Ickler
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Publication number: 20080047332Abstract: A cell for conducting electrochemiluminescence measurements is disclosed. The cell in one embodiment provides a measurement cell housing having a cavity, a fluid inlet channel for inducing fluid into the cavity and a fluid outlet channel for discharging fluid from the cavity at axial ends. The cell also provides at least one working electrode and a counter electrode on or in the cavity, and an optical viewing element for observing electrochemiluminescence effects in the cavity, wherein the fluid inlet channel has an at least approximately continuous curved course in a transition area to the cavity so that the fluid inlet channel at its end which is joined to the cavity is shaped in such a manner as to constitute a continuous course of the transition between the fluid inlet channel and the cavity to generate a largely steady flow profile when inducing fluid into the measurement cell cavity.Type: ApplicationFiled: August 23, 2007Publication date: February 28, 2008Applicant: Roche Diagnostics Operations, Inc.Inventors: Michael Kuhnl, Herbert Buschek, Reinhold Kramer, Petra Ickler
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Patent number: 6274304Abstract: There is provided a system for the preparation of liquids from at least one solid and at least one liquid phase. The system is composed of a vessel in which the solid or solids are located and a drying chamber which is connected to the vessel or can be connected to the vessel. The drying chamber is separated from the vessel interior by a separating means which is permeable to water vapour but is impermeable to liquids. The system is suitable for the production of liquids from moisture-sensitive solids. These solids can be stored in the vessel since the air humidity in the interior is lowered by the desiccant. The preparation of the liquid by addition of a liquid phase can be carried out in one and the same vessel since the desiccant is separated from the vessel interior.Type: GrantFiled: February 14, 1994Date of Patent: August 14, 2001Assignee: Roche Diagnostics GmbHInventors: Herbert Buschek, Michael Kuehnl, Roland Ihrig, Klaus Erler, Maria Cully
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Patent number: 5424212Abstract: Analysis system for the automatic analysis of body fluids for a plurality of different analytes (parameters). An analytical apparatus incorporates reaction vessels (8) which are transported on the apparatus to various handling stations (10 to 16). The system also includes liquid reagents, which are held in readiness on the apparatus in reagent vessels (9), their volume sufficing for a large number of analyses. In order to achieve a high degree of analytical accuracy with reduced probability of operating errors and without significant increasing of the overall system costs, a calibrator is stored ready for use in liquid form in a calibrator station (17) of the analytical apparatus, the calibration is initiated and carried out fully automatically (i.e. without human intervention) for the various parameters independently of one another.Type: GrantFiled: February 16, 1994Date of Patent: June 13, 1995Assignee: Boehringer Mannheim GmbHInventors: Judith Pinsl-Ober, Herbert Buschek, Klaus Erler
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Patent number: 4668622Abstract: The present invention provides phenolsulphonphthaleinyl-.beta.-D-galactosides of the general formula: ##STR1## wherein R.sup.1 to R.sup.4, which can be the same or different, are hydrogen or halogen atoms or nitro or amino groups, R.sup.5 to R.sup.12, which can be the same or different, are hydrogen or halogen atoms or lower alkyl, hydroxyl, lower alkoxy, carboxyl or nitro groups and M.sup.+ is a proton, an alkali metal, alkaline earth metal or ammonium ion.The present invention also provides a process for preparing these galactosides and diagnostic agents containing them.Type: GrantFiled: December 13, 1984Date of Patent: May 26, 1987Assignee: Boehringer Mannheim GmbHInventors: Manfred Kuhr, Rudolf Machat, Wolfgang Weckerle, Hans-Georg Batz, Rupert Herrmann, Wolfgang Kleeman, Herbert Buschek
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Patent number: 4557600Abstract: A process and a device for the centrifugal control and mixing of a limited volumes of fluid, especially in the rotor of a centrifugal analyzer, has at least one baffle chamber, in a flow canal for the fluid the volume of which is greater than the volume of fluid. It is so shaped that, when the device is rotated at a sufficiently high first speed of rotation, the fluid remains in it. An outlet canal is connected to the baffle chamber the fluid. At least a part thereof lies closer to the axis of rotation than the fluid surface during the rotation with the first speed of rotation. The walls of the outlet canal consist of a material which is wettable by the fluid and, in combination therewith, have cross-section which forces the fluid out of the baffle chamber; by boundary surface force when the device is rotated at a second, slower speed.Type: GrantFiled: August 30, 1982Date of Patent: December 10, 1985Assignee: Boehringer Mannheim GmbHInventors: Sigmar Klose, Manfred Pasch, Wolfgang Kleemann, Friedhelm Vieth, Herbert Buschek
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Patent number: 4476223Abstract: The present invention provides a process for the stabilization of an aqueous solution of cholesterol esterase from Pseudomonas, especially in the presence of a surface-active agent, wherein the enzyme is dissolved in a phosphate-free buffer which contains 10 to 200 mMol/liter of magnesium ions.Type: GrantFiled: December 23, 1982Date of Patent: October 9, 1984Assignee: Boehringer Mannheim GmbHInventors: Herbert Buschek, Helmut Schlumberger, Joachim Siedel
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Patent number: 4282001Abstract: For the removal of turbidities in reaction mixtures clouded by sample material, especially for photometric measurement, there are added to the reaction mixture:(a) at least one low molecular weight organic compound, such as an aromatic alcohol or amine, which contains an electronegative substituent, for example a phenol or naphthol, which is substituted with one or more halogen atoms and/or hydroxyl groups and(b) at least one detergent which dissolves to give without compound (a), a clear solution and which forms a sparingly soluble complex with component (a), such as a non-ionic polyethylene oxide adduct or a cationic detergent, especially an alkyl, aralkyl or alkylthio ether or an alkyl or aralkyl ester of a polyethylene oxide glycol containing 8 to 22 carbon atoms in the alkyl radical and 5 to 25 ethylene oxide units or an alkyl dimethyl benzyl ammonium chloride compound containing 8 to 22 carbon atoms in the alkyl radical,in an amount sufficient for the appearance of a precipitate of the complex, whereaftType: GrantFiled: April 4, 1979Date of Patent: August 4, 1981Assignee: Boehringer Mannheim GmbHInventors: Sigmar Klose, Herbert Buschek, Helmut Schlumberger