Patents by Inventor Herbert Dichtelmuller

Herbert Dichtelmuller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5147548
    Abstract: A sterile-filtered colostrum solution that contains casein is made by adjusting the pH of a colostrum solution to 2.5 to 3.5 and then filtering it clear and sterile. It is preferably first defatted, and adjusted to pH 5.5 to 8 after the acid treatment but before being filtered.
    Type: Grant
    Filed: August 14, 1991
    Date of Patent: September 15, 1992
    Assignee: Biotest Pharma GmbH
    Inventors: Henry Hies, Wolfgang Moller, Herbert Dichtelmuller, Wolfgang Stephan
  • Patent number: 5011695
    Abstract: A method for sterilizing blood, plasma or derivatives thereof by using vitamins or provitamins.
    Type: Grant
    Filed: February 16, 1989
    Date of Patent: April 30, 1991
    Assignee: Biotest Pharma GmbH
    Inventors: Herbert Dichtelmuller, Wolfgang Stephan
  • Patent number: 4965068
    Abstract: The present invention involves a polyvalent hyperimmunoglobulin preparation having activity against gram negative and gram positive bacteria. Such a polyvalent hyperimmunoglobulin preparation is prepared from plasma, serum or whole blood from donors. Donor selection is based upon titer against E. coli J5 antigen or against lipid A antigen.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: October 23, 1990
    Assignee: Biotest Pharma GmbH
    Inventors: Wolfgang Stephan, Herbert Dichtelmuller, Michael Kloft
  • Patent number: 4946648
    Abstract: A method of sterilizing plasma or plasma fractions, including fractions that contain the blood-coagulating Factor VIII by treatment with .beta.-propiolactone or ultraviolet radiation. Treatment with tri-n-butyl phosphate and sodium cholate or Tween 80 is carried out either prior to or simultaneously with the .beta.-propiolactone treatment or ultraviolet radiation.
    Type: Grant
    Filed: September 7, 1988
    Date of Patent: August 7, 1990
    Assignee: Biotest Pharma GmbH
    Inventors: Herbert Dichtelmuller, Wolfgang Moller, Wolfgang Stephan, Hans Schleussner
  • Patent number: 4877866
    Abstract: A method of producing a virus-safe, storage-stable, and intravenously tolerable immunoglobulin-G preparation. The object is to make the method appropriate for industrial-scale production and economical by means of the enrichment and multistage purification of a plasma that has had the coagulation factors removed from it or of a plasma fraction or serum fraction that contains immunoglobulin G accompanied by treatment with ion exchangers and by ultrafiltration. The precipitant is eliminated, by means of diafiltration or gelfiltration, either from the plasma that has had the coagulation factors removed from it or from the plasma fraction that contains the immunoglobulin G, and the desired ion composition is established. The resulting protein solution is subjected to fractionation over an ion exchanger to separate the immunoglobulin G.
    Type: Grant
    Filed: November 18, 1987
    Date of Patent: October 31, 1989
    Assignee: Biotest Pharma GmbH
    Inventors: Dieter Rudnick, Norbert Kothe, Herbert Dichtelmuller, Detlef Piechaczek, Wolfgang Stephan, Hans Schleussner
  • Patent number: 4734279
    Abstract: A compositon for treating diseases which comprises a therapeutically effective amount of an antibacterial, antiviral, or antimycotic agent, antitrypsin, antithrombin, interferon, or lysozyme, and an immunoenhancing amount of immunoglobulins IgG, IgM, and IgA, and a method of therapy of a mammal in need thereof are disclosed.
    Type: Grant
    Filed: July 19, 1985
    Date of Patent: March 29, 1988
    Assignee: Biotest Pharma GmbH
    Inventors: Wolfgang Stephan, Herbert Dichtelmuller, Alexander Thrun, Hans Schleussner
  • Patent number: 4644056
    Abstract: A method of preparing a solution of lactic or colostric immunoglobulins or both by processing milk or colostrum or both accompanied by precipitation of the caseins, characterized in that milk or colostrum or both are acidified to a pH of 4.0-5.5, subjected to cross-flow filtration in a filtration unit with a mean pore size of 0.1-1.2 .mu.m, and the low-molecular components removed by means of further cross-flow filtration in another filtration unit with a limit of separation of 5 000-80 000 daltons, as well as an agent for treating bacterial and viral infections that consists of a solution obtained by means of said method.
    Type: Grant
    Filed: September 3, 1985
    Date of Patent: February 17, 1987
    Assignee: Biotest Pharma GmbH
    Inventors: Norbert Kothe, Herbert Dichtelmuller, Wolfgang Stephan, Bertram Eichentopf