Patents by Inventor Herbert Hurwitz

Herbert Hurwitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of predicting responsiveness of a cancer to a VEGF targeting agent and methods of prognosing and treating cancer
    Patent number: 11499973
    Abstract: Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided. The methods may include obtaining a sample from the subject, determining an expression level of at least one biomarker selected from the group consisting of VEGF-D and PlGF in a sample from the subject, comparing the expression level of the biomarker in the sample to a reference level of the biomarker, and predicting the responsiveness of the cancer to treatment with the cancer therapy including a VEGF targeting agent. Optionally, the methods may further include administering a VEGF target agent and/or an anticancer or chemotherapy agent to the subject. Additional methods of prognosing and treating a cancer in a subject are also provided.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: November 15, 2022
    Assignee: Duke University
    Inventors: Andrew Nixon, Chris Brady, Yingmiao Liu, Herbert Hurwitz, Kouros Owzar, Alexander Sibley, Chen Jiang, Ace Hatch, Mark Starr
  • Methods of Predicting Responsiveness of a Cancer to a VEGF Targeting Agent and Methods of Prognosing and Treating Cancer
    Publication number: 20190204320
    Abstract: Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided. The methods may include obtaining a sample from the subject, determining an expression level of at least one biomarker selected from the group consisting of VEGF-D and PlGF in a sample from the subject, comparing the expression level of the biomarker in the sample to a reference level of the biomarker, and predicting the responsiveness of the cancer to treatment with the cancer therapy including a VEGF targeting agent. Optionally, the methods may further include administering a VEGF target agent and/or an anticancer or chemotherapy agent to the subject. Additional methods of prognosing and treating a cancer in a subject are also provided.
    Type: Application
    Filed: May 17, 2017
    Publication date: July 4, 2019
    Applicant: Duke University
    Inventors: Andrew Nixon, Chris Brady, Yingmiao Liu, Herbert Hurwitz, Kouros Owzar, Alexander Sibley, Chen Jiang, Ace Hatch, Mark Starr
  • Compositions and methods for the treatment of drug-induced hand-foot syndrome
    Patent number: 9629845
    Abstract: The present invention provides methods of treating, ameliorating or preventing hand-foot syndrome in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a phosphodiesterase inhibitor.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: April 25, 2017
    Assignee: Duke University
    Inventor: Herbert Hurwitz
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF DRUG-INDUCED HAND-FOOT SYNDROME
    Publication number: 20160074405
    Abstract: The present invention provides methods of treating, ameliorating or preventing hand-foot syndrome in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a phosphodiesterase inhibitor.
    Type: Application
    Filed: November 19, 2015
    Publication date: March 17, 2016
    Inventor: Herbert Hurwitz
  • Compositions and methods for the treatment of drug-induced hand-foot syndrome
    Patent number: 9220713
    Abstract: The present invention provides methods of treating, ameliorating or preventing hand-foot syndrome in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a phosphodiesterase inhibitor.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: December 29, 2015
    Assignee: Duke University
    Inventor: Herbert Hurwitz
  • Compositions and Methods for the Treatment of Drug-Induced Hand-Foot Syndrome
    Publication number: 20120258970
    Abstract: The present invention provides methods of treating, ameliorating or preventing hand-foot syndrome in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a phosphodiesterase inhibitor.
    Type: Application
    Filed: October 15, 2010
    Publication date: October 11, 2012
    Inventor: Herbert Hurwitz