Patents by Inventor Herbert John Havera

Herbert John Havera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for using 3-substituted-5-phenyl-5-pyridyl hydantoins as antiarrhythmic agents
    Patent number: 4061760
    Abstract: Compounds having the generic structure, ##STR1## and their nontoxic, pharmacologically acceptable salts are useful in the chemotherapy of arrhythmias in individuals for whom such therapy is indicated. In the preceding structural formula: R.sup.1 is a 2-pyridyl, 3-pyridyl, or 4-pyridyl radical; n is an integer of the set 1-3; and R.sup.2 is a hydrogen atom, a hydroxyl, or an equivalent alkoxyl group having from 1 to 3 carbon atoms.
    Type: Grant
    Filed: October 4, 1976
    Date of Patent: December 6, 1977
    Assignee: Miles Laboratories, Inc.
    Inventors: Herbert John Havera, Wallace Glenn Strycker
  • Therapeutic method of treating cardiac arrhythmias utilizing 3-substituted diphenylhydantoins
    Patent number: 4006232
    Abstract: 3-substituted-5,5-diphenylhydantoin derivatives in which the 5,5-diphenylhydantoin moiety is attached at C.sub.3 by a loweralkylene bridge to a 4-phenyl-1-piperidyl, 4-hydroxy-4-phenyl-1-piperidyl, 4-phenyl-1,2,3,6-tetrahydropyridyl, 4-phenyl-1-piperazinyl, or loweralkylamino group are useful in the treatment of cardiac arrhythmias in mammals. One or both of the 5,5-diphenyl substituents optionally can be substituted in the ortho-, meta-, or para-positions with halogeno, lowerakyl, loweralkoxy, amino or nitro groups.
    Type: Grant
    Filed: November 15, 1974
    Date of Patent: February 1, 1977
    Assignee: Miles Laboratories, Inc.
    Inventors: Shin Hayao, Herbert John Havera, Wallace Glenn Strycker
  • Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[.alpha.]quinolizines
    Patent number: 3995041
    Abstract: 2-Substituted-hydroxyanilino-hexahydro-2H-benzo[.alpha.]quinolizines of the structural formula, ##SPC1##In which R.sup.1 is a hydrogen atom or an alkanoyl group of 2 to 4 carbon atoms and each of substituents R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 is a hydrogen atom, a hydroxyl, or a methyl group, such that at least one of the latter substituents is a hydroxyl group, exhibit coronary vasodilating activity.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: November 30, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Herbert John Havera, Richard Don Johnson, Horacio Vidrio
  • 3-Substituted -5-phenyl-5-pyridyl hydantoins
    Patent number: 3994904
    Abstract: Compounds having the generic structure, ##SPC1##And their nontoxic, pharmacologically acceptable salts are useful in the chemotherapy of arrhythmias in individuals for whom such therapy is indicated. In the preceding structural formula: R.sup.1 is a 2-pyridyl, 3-pyridyl, or 4-pyridyl radical; n is an integer of the set 1-3; and R.sup.2 is a hydrogen atom, a hydroxyl, or an equivalent alkoxyl group having from 1 to 3 carbon atoms.
    Type: Grant
    Filed: March 8, 1976
    Date of Patent: November 30, 1976
    Assignee: Miles Laboratories, Inc.
    Inventors: Herbert John Havera, Wallace Glenn Strycker