Patents by Inventor Herbert K. Struemper

Herbert K. Struemper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for computer modeling a joint
    Patent number: 7472050
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: December 30, 2008
    Assignee: Entelos, Inc.
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, II, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper
  • Method and Apparatus for Computer Modeling of an Adaptive Immune Response
    Publication number: 20080201122
    Abstract: The present invention relates generally to a computer model of an adaptive immune response. One embodiment of the invention relates to a computer model of an adaptive immune response within the framework of signals conveyed at the site of antigen exposure. Another embodiment of the model includes a representation of complex physiological regulatory mechanisms related to, for example, cellular dynamics, mediator production, antigen-presenting cell (APC) recruitment, APC maturation, lymphocyte activation, lymphocyte trafficking, and/or lymphocyte effector function. In another embodiment, the model can account for mediator production in response to antigen within a chronically inflamed peripheral tissue, as well as the regulatory effects of mediators on APC and lymphocyte population dynamics, including maturation, activation, and apoptosis, and the regulatory effects of mediators produced by APCs and lymphocytes on a chronically inflamed peripheral tissue.
    Type: Application
    Filed: October 4, 2007
    Publication date: August 21, 2008
    Inventors: Scott D. Kelly, David J. Klinke, Clement Leong, Annette K. Lewis, Miles S. Okino, Thomas S. Paterson, Lisl K.M. Shoda, Cynthia Stokes, Herbert K. Struemper
  • Method and apparatus for computer modeling a joint
    Patent number: 6862561
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: March 1, 2005
    Assignee: Entelos, Inc.
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, II, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper
  • Method and apparatus for computer modeling of an adaptive immune response
    Publication number: 20030104475
    Abstract: The present invention relates generally to a computer model of an adaptive immune response. One embodiment of the invention relates to a computer model of an adaptive immune response within the framework of signals conveyed at the site of antigen exposure. Another embodiment of the model includes a representation of complex physiological regulatory mechanisms related to, for example, cellular dynamics, mediator production, antigen-presenting cell (APC) recruitment, APC maturation, lymphocyte activation, lymphocyte trafficking, and/or lymphocyte effector function. In another embodiment, the model can account for mediator production in response to antigen within a chronically inflamed peripheral tissue, as well as the regulatory effects of mediators on APC and lymphocyte population dynamics, including maturation, activation, and apoptosis, and the regulatory effects of mediators produced by APCs and lymphocytes on a chronically inflamed peripheral tissue.
    Type: Application
    Filed: June 28, 2002
    Publication date: June 5, 2003
    Inventors: Scott D. Kelly, David J. Klinke, Clement Leong, Annette K. Lewis, Miles S. Okino, Thomas S. Paterson, Lisl K.M. Shoda, Cynthia Stokes, Herbert K. Struemper
  • Method and apparatus for computer modeling a joint
    Publication number: 20030078759
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Application
    Filed: May 22, 2002
    Publication date: April 24, 2003
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper