Patents by Inventor Herbert Lyerly

Herbert Lyerly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED INHIBITION OF DKK3 TO SENSITIZE TUMORS TO IMMUNOTHERAPY
    Publication number: 20240165228
    Abstract: Disclosed herein are methods of methods of inhibiting growth of a dormant cancer cell comprising administering an effective amount of a DKK3 inhibitor to a subject in need thereof to inhibit growth of the dormant cancer cell.
    Type: Application
    Filed: November 17, 2023
    Publication date: May 23, 2024
    Inventors: Zachary Hartman, Herbert Lyerly, Timothy Trotter
  • COMPOSITIONS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF HER2+ CANCERS
    Publication number: 20220049015
    Abstract: The present disclosure provides compositions and methods for the treatment of HER2+ cancers in a subject. The present disclosure provides a combination therapy of a HER2 antibody and a CD47 antagonist. The method activate an anti-tumor response that comprises activating the antibody dependent cellular phagocytosis (ADCP) within the subject.
    Type: Application
    Filed: November 27, 2019
    Publication date: February 17, 2022
    Applicant: DUKE UNIVERSITY
    Inventors: Herbert Lyerly, Zachary Hartman