Patents by Inventor Herbert R. Roth

Herbert R. Roth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols
    Patent number: 4517188
    Abstract: 1-(4-Pyrimidinyloxy)-3-(hetarylalkylamino)-2-propanols are cardiovascular agents having a range of vasodilator and adrenergic beta-receptor blocking activities making these compounds useful anti-hypertensive agents. Preferred compounds bear a hydrazino or hydrazono substituent in the 2- position of the pyrimidine ring.
    Type: Grant
    Filed: May 9, 1983
    Date of Patent: May 14, 1985
    Assignee: Mead Johnson & Company
    Inventors: John E. Lawson, William L. Matier, Herbert R. Roth
  • Indolyl cyanomethylphenethanolamines
    Patent number: 4148908
    Abstract: Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-[1-hydroxy-2-[(1,1-dimethyl-2-phenylethyl)amino]ethyl]-benzene acetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.
    Type: Grant
    Filed: September 22, 1977
    Date of Patent: April 10, 1979
    Assignee: Mead Johnson & Company
    Inventors: William E. Kreighbaum, William L. Matier, Herbert R. Roth
  • Cyanomethylphenethanolamines
    Patent number: 4055658
    Abstract: Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-[1-hydroxy-2-[(1,1-dimethyl-2-phenylethyl)amino]ethyl]-benzene acetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.
    Type: Grant
    Filed: May 17, 1976
    Date of Patent: October 25, 1977
    Assignee: Mead Johnson & Company
    Inventors: William E. Kreighbaum, William L. Matier, Herbert R. Roth
  • Antihypertensive 4'-[1-hydroxy-2-[(1-phenoxy ethyl)-amino]ethyl]methanesulfonanilide and salts thereof and therapeutic use
    Patent number: 4044150
    Abstract: The sulfonamidophenethanolamine 4'-[1-hydroxy-2-[(2-phenoxyethyl)amino]ethyl]methanesulfonanilide is an antihypertensive beta-adrenergic blocking agent selectively lowering blood pressure with minimal reduction of heart rate.
    Type: Grant
    Filed: June 18, 1976
    Date of Patent: August 23, 1977
    Assignee: Mead Johnson & Company
    Inventors: William E. Kreighbaum, Herbert R. Roth
  • Anorexigenic process and composition
    Patent number: 3993776
    Abstract: 2'-Hydroxy-5'-[1-hydroxy-2-(2-methyl-1-phenyl-2-propylamino)ethyl]methanesu lfonanilide is a potent anorexigenic agent and orally active bronchodilator.
    Type: Grant
    Filed: October 21, 1975
    Date of Patent: November 23, 1976
    Assignee: Mead Johnson & Company
    Inventors: William T. Comer, Herbert R. Roth