Patents by Inventor Herbert RUNNELS

Herbert RUNNELS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING DUCHENNE MUSCULAR DYSTROPHY USING AAV MINI-DYSTROPHIN GENE THERAPY
    Publication number: 20230241248
    Abstract: The disclosure describes methods of treating humans with Duchenne muscular dystrophy by providing doses of an AAV9 vector that expresses a mini-dystrophin protein in transduced muscle cells.
    Type: Application
    Filed: June 25, 2020
    Publication date: August 3, 2023
    Inventors: Phoebe Arnold BALDUS, David Roger BEIDLER, Michael BINKS, Suzanne C. DEMARCO, Rong HUANG, Tara MCDONNELL MOOREHEAD, Srividya NEELAKANTAN, Hendrik NEUBERT, Herbert RUNNELS, Savita SANKAR, Tatiana G. SHAPKINA, Sarah Paige SHERLOCK, Laurence Oliver WHITELEY, Florence Hiu-Ling YONG
  • Antibodies to IGF-I receptor for the treatment of cancers
    Publication number: 20040202655
    Abstract: Antibodies specific for Insulin-like growth factor I receptor (IGF-IR) are provided. The antibodies and fragments thereof may block binding of IGF-I to IGF-IR. Antagonist antibodies can be employed to block binding of IGF-I to IGF-IR or substantially inhibit IGF-IR activation. The IGF-IR antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer, inflammation, and pathological liver conditions, using the IGF-IR antibodies are also provided.
    Type: Application
    Filed: March 12, 2004
    Publication date: October 14, 2004
    Inventors: Phillip A. Morton, John A. Arbuckle, Karen S. Bailey, Peter J. Nicastro, Herbert A. Runnels