Patents by Inventor Herbert S. Bresler
Herbert S. Bresler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240123222Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: ApplicationFiled: December 20, 2023Publication date: April 18, 2024Inventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Patent number: 11883656Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: GrantFiled: October 20, 2022Date of Patent: January 30, 2024Assignee: BATTELLE MEMORIAL INSTITUTEInventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Publication number: 20230047319Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: ApplicationFiled: October 20, 2022Publication date: February 16, 2023Inventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Patent number: 11504531Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: GrantFiled: January 13, 2022Date of Patent: November 22, 2022Assignee: BATTELLE MEMORIAL INSTITUTEInventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Publication number: 20220134098Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: ApplicationFiled: January 13, 2022Publication date: May 5, 2022Inventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Patent number: 11266833Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.Type: GrantFiled: May 14, 2021Date of Patent: March 8, 2022Inventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
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Publication number: 20220031245Abstract: A device for functional electrical stimulation (FES), neuromuscular electrical stimulation (NMES), and/or electromyography (EMG) readout includes a sleeve sized and shaped to be worn on a human arm and comprising an inner sleeve and an outer sleeve. The inner sleeve has openings formed therein, and has an exposed side positioned to contact skin and an opposite backside facing the outer sleeve. Electrode strips each comprise a linear circuit board on which a row of electrodes is mounted. The electrode strips are detachably and selectively mountable to the inner sleeve in a plurality of different orientations. The electrode strips are mountable on the inner sleeve with the linear circuit boards disposed on the backside of the inner sleeve between the inner sleeve and the outer sleeve and the electrodes passing through the openings of the inner sleeve so as to be positioned to contact skin.Type: ApplicationFiled: July 30, 2021Publication date: February 3, 2022Inventor: Herbert S. Bresler
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Publication number: 20200121195Abstract: The present disclosure relates generally to a system and method for detecting or indicating a state of visual impairment of a patient due to a medical condition, and more particularly to a method, system and application or software program configured to create a virtual-reality (“VR”) environment that implements visual symptom tests, and which utilizes eye tracking technology to detect or indicate visual symptoms and associated medical conditions.Type: ApplicationFiled: October 17, 2019Publication date: April 23, 2020Inventors: Herbert S. Bresler, Scott M. Gibbons, Aaron Frank, Matthew Kromer, Bohdan Paselsky
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Patent number: 10254562Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.Type: GrantFiled: March 11, 2016Date of Patent: April 9, 2019Assignee: BATTELLE MEMORIAL INSTITUTEInventors: Herbert S. Bresler, Erik Edwards, Amy M. Heintz, John S. Laudo, Alexander C. Morrow, Steven M. Risser
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Publication number: 20160221283Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.Type: ApplicationFiled: September 10, 2014Publication date: August 4, 2016Inventors: Herbert S. Bresler, Erik Edwards, Amy M. Heintz, John S. Laudo, Alexander C. Morrow, Steven M. Risser
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Publication number: 20160195735Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.Type: ApplicationFiled: March 11, 2016Publication date: July 7, 2016Inventors: Herbert S. Bresler, Erik Edwards, Amy M. Heintz, John S. Laudo, Alexander C. Morrow, Steven M. Risser
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Patent number: 8116985Abstract: An automated blood or bodily fluid sampling machine for collecting, measuring and monitoring real time samples from test animals during dosing of the animals, automatically provides real-time adjustment of dosing during testing. Such automated blood or bodily fluid sampling is performed in tandem with implanted physiological monitoring devices to monitor biological and physiological parameters in restrained or freely-moving test animals. The real-time feedback provides for dosing adjustment within testing protocols.Type: GrantFiled: March 19, 2007Date of Patent: February 14, 2012Assignee: Battelle Memorial InstituteInventors: Jerry D. Johnson, Steven W. Graves, Seongwon Hong, Herbert S. Bresler, Michael J. Brooker, R. Mark Gritz
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Patent number: 7749741Abstract: A tissue dissociation device (10) includes a container (12) having a sterile interior for holding the tissue to be dissociated and a liquid medium. The device (10) also includes a dissociation element (54), inside the container (12), for engaging the tissue to cause dissociation of the tissue. The device (10) also includes a resistive element (81), inside the container (12), for resisting movement of the tissue in response to the engagement by the dissociation element (54). Relative motion between and the resulting resistance provided by the resistive element (81) allows the dissociation element (54) to effectively dissociate the tissue. A powered tissue dissociation device includes a power source operatively connected to the dissociation element (54) for causing the dissociation element (54) to move into engagement with the tissue.Type: GrantFiled: September 21, 2004Date of Patent: July 6, 2010Assignee: Battelle Memorial InstituteInventors: Lawrence Bullen, Herbert S. Bresler, Daniel A. Kramer
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Publication number: 20090007281Abstract: Methods of diagnosis, markers, and screening techniques and animal models for assessing the severity and/or progression or regression of chronic obstructive pulmonary disease (COPD) and COPD-related diseases are disclosed.Type: ApplicationFiled: January 16, 2007Publication date: January 1, 2009Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Roger Alan Renne, Kyeonghee Monica Lee, Katrina Marie Waters, Quanxin Meng, David L. Springer, Sam Jens Harbo, Katherine M. Gideon, Joel G. Pounds, Herbert S. Bresler, Don S. Daly
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Publication number: 20020106375Abstract: A new factor, Factor C, is produced by the activated-expanded autologous cells of cancer patients, HIV-1 infected patients, CFS patients, healthy patients, etc. Factor C has a molecular weight of about 70,000 to 80,000 daltons, is heat stable, has an amino acid sequence that is absent from the National Center for Biotechnology Information database, and whose amino acid sequence is not homologous to TNF family ligands. Factor C is derived from CD4 cells in a much greater quantity than from CD8 cells, and is derived from lymph cells in a greater quantity than from PBL cells. A double activation and expansion (activation-expansion) process using immobilized and soluble anti-CD3 mAb makes such Factor C. Factor C appears to inhibit transcription in virally-infected and tumor cells, and stimulates the proliferation of normal lymphocytes.Type: ApplicationFiled: November 30, 2000Publication date: August 8, 2002Inventors: Pierre L. Triozzi, John L. Ridihalgh, Herbert S. Bresler
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Patent number: 5498537Abstract: The application concerns a method for the serum-free production of packaged and infectious vital vectors in an artificial capillary system cartridge. The invention further concerns transducing target cells with the vital vectors. The invention is particularly suitable for producing transduced target cells free of adherent serum proteins.Type: GrantFiled: March 9, 1994Date of Patent: March 12, 1996Assignee: Cellco, Inc.Inventors: Herbert S. Bresler, Richard A. Knazek