Patents by Inventor Herbert Stadler

Herbert Stadler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250020556
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Application
    Filed: October 1, 2024
    Publication date: January 16, 2025
    Applicant: Juno Therapeutics GmbH
    Inventor: Herbert STADLER
  • Patent number: 12135265
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 5, 2024
    Assignee: Juno Therapeutics GmbH
    Inventor: Herbert Stadler
  • Publication number: 20240329039
    Abstract: Provided are affinity-based methods of isolating biological entities via a surface antigen from a sample with non-chromatographic and chromatographic methods being provided. Also provided is a dextran polymer, kits for use in the method of isolating a biological entity and an apparatus for performing the methods.
    Type: Application
    Filed: March 19, 2024
    Publication date: October 3, 2024
    Inventor: Herbert STADLER
  • Patent number: 12066365
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: August 20, 2024
    Assignee: Juno Therapeutics GmbH
    Inventor: Herbert Stadler
  • Patent number: 11965882
    Abstract: Provided are affinity-based methods of isolating biological entities via a surface antigen from a sample with non-chromatographic and chromatographic methods being provided. Also provided is a dextran polymer, kits for use in the method of isolating a biological entity and an apparatus for performing the methods.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: April 23, 2024
    Assignee: CELL.COPEDIA GMBH
    Inventor: Herbert Stadler
  • Publication number: 20230210895
    Abstract: Provided are novel biologically active blood fractions that can be used for the treatment of damaged epithelial surfaces and that are nanofilterable as well as corresponding compositions and eye drops and methods of their manufacture.
    Type: Application
    Filed: August 3, 2021
    Publication date: July 6, 2023
    Inventors: Herbert STADLER, Stefan SCHNEIDER, Andrea JOCHHEIM-RICHTER, Ingeborg SILLABER
  • Publication number: 20230140446
    Abstract: Provided are affinity-based methods of isolating biological entities via a surface antigen from a sample with non-chromatographic and chromatographic methods being provided. Also provided is a dextran polymer, kits for use in the method of isolating a biological entity and an apparatus for performing the methods.
    Type: Application
    Filed: February 1, 2021
    Publication date: May 4, 2023
    Inventor: Herbert STADLER
  • Patent number: 10369561
    Abstract: A first aspect of the invention relates to a syringe housing which can have the following elements: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: August 6, 2019
    Assignee: Cell.Copedia GmbH
    Inventors: Herbert Stadler, Wilhelm Gerdes, Sabine Przibilla
  • Publication number: 20190234844
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Application
    Filed: December 21, 2018
    Publication date: August 1, 2019
    Applicant: Juno Therapeutics GmbH
    Inventor: Herbert STADLER
  • Publication number: 20190226951
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 25, 2019
    Applicant: Juno Therapeutics GmbH
    Inventor: Herbert STADLER
  • Patent number: 10228312
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: March 12, 2019
    Assignee: Juno Therapeutics GmbH
    Inventor: Herbert Stadler
  • Publication number: 20170361314
    Abstract: A first aspect of the invention relates to a syringe housing which can have the following elements: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the
    Type: Application
    Filed: December 10, 2015
    Publication date: December 21, 2017
    Inventors: Herbert Stadler, Wilhelm Gerdes, Sabine Przibilla
  • Publication number: 20150024411
    Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.
    Type: Application
    Filed: February 25, 2013
    Publication date: January 22, 2015
    Inventor: Herbert Stadler
  • Patent number: 4783956
    Abstract: In a method and an apparatus for producing a yarn by means of friction spinning drums, a fiber sliver is transformed into a body of fibers and transferred to a first perforated friction spinning drum of such friction spinning drums. At this first perforated friction spinning drum, the fibers are entrained by a suction air stream, produced by a suction passage located in the first perforated friction spinning drum, and are then fed into a converging space formed by and between the friction spinning drums. In this converging space the fibers are twisted into a spun yarn. The spun yarn is withdrawn by withdrawal rollers located near end faces of the friction spinning drums. The suction air stream required for entraining or catching the fibers is limited by walls forming the suction passage. The advantage of this apparatus is that the fibers are mechanically guided over the whole length of their travel path, i.e. from the body of fibers to the twisted yarn. As a result, the fibers never swim freely.
    Type: Grant
    Filed: December 15, 1986
    Date of Patent: November 15, 1988
    Assignee: Rieter Machine Works Limited
    Inventor: Herbert Stadler