Patents by Inventor Herman Jan Pel

Herman Jan Pel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220186264
    Abstract: The invention relates to a process for producing a fermentation broth by culturing a microorganism.
    Type: Application
    Filed: March 11, 2020
    Publication date: June 16, 2022
    Inventors: Herman Jan PEL, Maaike APPELDOORN, Rolf POLDERMANS
  • Publication number: 20210189360
    Abstract: The application relates to an enzyme composition, a process for the preparation thereof and the use of the enzyme composition in enzymatic hydrolysis.
    Type: Application
    Filed: March 5, 2021
    Publication date: June 24, 2021
    Inventors: Loes Elizabeth BEVERS, Maaike APPELDOORN, Margot Elisabeth Francoise SCHOONEVELD-BERGMANS, Herman Jan PEL
  • Patent number: 10865407
    Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via the cleavage sites, thereby to prepare two or more standardized expression cassettes.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: December 15, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Andries Roubos, Herman Jan Pel, Bernard Meijrink
  • Publication number: 20190284594
    Abstract: The application relates to an enzyme composition, a process for the preparation thereof and the use of the enzyme composition in enzymatic hydrolysis.
    Type: Application
    Filed: November 23, 2017
    Publication date: September 19, 2019
    Inventors: Loes Elizabeth BEVERS, Maaike APPELDOORN, Margot Elisabeth Francoise SCHOONEVELD-BERGMANS, Herman Jan PEL
  • Publication number: 20190276809
    Abstract: The application relates to an enzyme composition, a process for the preparation thereof and the use of the enzyme composition in enzymatic hydrolysis.
    Type: Application
    Filed: November 23, 2017
    Publication date: September 12, 2019
    Inventors: Loes Elizabeth BEVERS, Maaike APPELDOORN, Margot Elisabeth Francoise SCHOONEVELD-BERGMANS, Herman Jan PEL
  • Publication number: 20170314011
    Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via the cleavage sites, thereby to prepare two or more standardized expression cassettes.
    Type: Application
    Filed: July 13, 2017
    Publication date: November 2, 2017
    Inventors: Johannes Andries ROUBOS, Herman Jan Pel, Bernard Meijrink
  • Patent number: 9738890
    Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via cleavage sites, thereby to prepare two or more standardized expression cassettes.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: August 22, 2017
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Andries Roubos, Herman Jan Pel, Bernard Meijrink
  • Patent number: 9322045
    Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: April 26, 2016
    Assignee: DSM IP ASSETS B.V.
    Inventors: Noël Nicolaas Maria Elisabeth Van Peij, Herman Jan Pel, Thibaut José Wenzel, Adriana Marina Riemens, Ilse De Lange
  • Publication number: 20150197760
    Abstract: The present invention relates to isolated Rasamsonia promoter DNA sequences, to DNA constructs, vectors, and host cells comprising these promoters in operative association with coding sequences. The present invention also relates to methods for expressing a gene and/or producing a biological compound using the new promoters isolated. The present invention also relates to methods for altering the transcription level and/or regulation of an endogenous gene using the new promoter of the invention.
    Type: Application
    Filed: June 17, 2013
    Publication date: July 16, 2015
    Inventors: Alrik Pieter Los, Wilbert Herman Marie Heijne, Herman Jan Pel, Robbertus Antonius Damveld, Brenda Vonk
  • Publication number: 20150050696
    Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via cleavage sites, thereby to prepare two or more standardized expression cassettes.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 19, 2015
    Inventors: Johannes Andries Roubos, Herman Jan Pel, Bernard Meijrink
  • Publication number: 20140248662
    Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.
    Type: Application
    Filed: April 10, 2014
    Publication date: September 4, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Noël Nicolaas Maria Elisabeth VAN PEIJ, Herman Jan PEL, Thibaut Jose WENZEL, Adriana Marina RIEMENS, Ilse DE LANGE
  • Patent number: 8734782
    Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: May 27, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Noël Nicolass Maria Elisabeth Van Peij, Herman Jan Pel, Thibaut José Wenzel, Adriana Marina Riemens, Ilse De Lange
  • Publication number: 20130011876
    Abstract: The invention relates to a process for preparing filamentous fungal strains having a sexual cycle, wherein an acceptor filamentous fungal strain, having no or one type MAT locus, is subjected to recombination in which one or more mating type locus genes and optionally sex related genes, from other species than the acceptor filamentous fungal strain, is introduced into the acceptor filamentous fungal strain to produce a filamentous fungal strain having a sexual cycle.
    Type: Application
    Filed: January 12, 2011
    Publication date: January 10, 2013
    Applicant: DSM IP ASSETTS, B.V.
    Inventors: Peter Jozef Ida Van De Vondervoort, Herman Jan Pel, Paul Stanley Dyer
  • Publication number: 20120190066
    Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.
    Type: Application
    Filed: July 1, 2010
    Publication date: July 26, 2012
    Applicant: DSM IP ASSETS B.V.
    Inventors: Noël Nicolass Maria Elisabeth Van Peij, Herman Jan Pel, Thibaut José Wenzel, Adriana Marina Riemens, Ilse De Lange
  • Publication number: 20100317599
    Abstract: The present invention describes a polypeptide, comprising at least one repeat domain, further comprising a recombinant peptide of interest. The present invention further describes a process for the production of a recombinant peptide of interest. The invention further describes the use of a repeat protein for the production of a recombinant peptide of interest.
    Type: Application
    Filed: January 29, 2009
    Publication date: December 16, 2010
    Inventors: Alrik Pieter Los, Jan Metske Laan Van Der, Cornelis Maria Jacobus Sagt, Herman Jan Pel
  • Patent number: 7527953
    Abstract: Four new genes, and the enzymes that they encode, are disclosed, which are present in Propionibacterium freudenreichii, and which are involved in at least five steps in the biosynthetic pathway of vitamin B12. The four enzymes are: A: cobyrinic acid a, c-diamide synthase; B: a bifunctional enzyme, which is a cobinamide kinase and a cobinamide phosphate guanyl transferase; C: a cobalamin 5-phosphate synthase; and D: an adenosyl transferase. Genes encoding the four enzymes can be placed in Propionibacteria shuttle vectors and used to transform Propionibacteria hosts, in order to improve the production of vitamin B12 or a precursor thereof on an industrial scale during fermentation.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: May 5, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Herman Jan Pel, Sylvia Hopper