Abstract: Intraocular lenses and methods producing the same are provided. The intraocular lens includes an optic and a haptic that are integrally formed together. The haptic has a polyimide coating. The polyimide coating promotes fibrosis in the surrounding eye tissue to enhance the anchoring of the IOL after it is implanted in an eye.

Abstract: A contact lens with enhanced UV blocking to meet ANSI Class 1 specifications includes enhanced effective amounts of two different UV absorbing compounds. One UV absorber is a benzotriazole derivative, and the other UV absorber is a benzophenone derivative.

Abstract: Contact lenses, intraocular lenses and transparent plastic with enhanced UV blocking to meet ANSI Class 1 specifications include enhanced effective amounts of two different UV absorbing compounds. One UV absorber is a benzotriazole derivative, and the other UV absorber is a benzophenone derivative. The lenses are made from a polymer that incorporates both of these UV absorbers.

Abstract: Novel O-alkylsilyl derivatives of macrolide antibiotics are disclosed. These compounds have markedly superior taste properties when compared to the corresponding parent compounds.

Abstract: A process for inducing the production of endogenous interferon in a vertebrate animal which comprises parenterally, intranasally or topically adminstering to the animal an interferon-inducing effective amount of composition containing as the essential active ingredient a compound of the formula ##STR1## or a non-toxic acid addition salt thereof wherein R.sub.7 and R.sub.8 are each alkyl of from 12 to 30 carbon atoms and Z is selected from the group consisting of N-(lower alkyl)-piperazino and N-(W-hydroxy-lower alkyl)-piperazino, said lower alkyl groups having from 1 to 4 carbon atoms.

Abstract: Combating viral infections in vertebrate animals by administering to the animals a monoamine, a diamine or a triamine.

Abstract: The 11a-dehalogenation of 11a-halo-6-methylenetetracyclines by treating them with a secondary or a tertiary phosphine or a tertiary phosphite.

Abstract: Combating viral infections in vertebrate animals by administering to the animals an amine selected from those having the formulae: ##STR1## and the non-toxic acid addition salts thereof wherein R.sub.1 is selected from the group consisting of alkyl of from 1 to 20 carbon atoms, aralkyl, aryloxyalkyl, hydroxyalkyl of from 2 to 8 carbon atoms and ##STR2## R.sub.2 is selected from the group consisting of alkyl of from 12 to 20 carbon atoms, aralkyl and aryloxyalkyl of from 12 to 24 carbon atoms and ##STR3## R.sup.o is alkoxy of from 1 to 18 carbon atoms; EACH OF R' and R" is selected from the group consisting of hydrogen, alkyl, alkoxy of from 1 to 18 carbon atoms; R' and R" when taken together are methylenedioxy;Provided that the total number of carbon atoms in R.sup.o, R' and R" is from 5 to 48;R.sub.3 is selected from the group consisting of hydrogen, alkyl of from 1 to 20 carbon atoms, hydroxyalkyl of from 2 to 8 carbon atoms, phenylcarbamoyloxy(lower alkyl), .omega.

Abstract: Compounds of the formula ##STR1## or a non-toxic acid addition salt thereof wherein R.sub.1 is alkyl of from 1 to 20 carbon atoms;R.sub.2 is alkyl of from 12 to 20 carbon atoms;R.sub.3 is selected from the group consisting of hydrogen and hydroxyalkyl of from 2 to 8 carbon atoms; andR.sub.4 is selected from the group consisting of hydrogen, alkyl of from 1 to 8 carbon atoms and hydroxyalkyl of from 2 to 8 carbon atoms, said compounds are useful for combating viral infections in vertebrate animals.

Abstract: Hydrogenation of a mixture prepared from a 6-deoxy-6-demethyl-6-methylenetetracycline compound, and a catalytic amount of a dicarboxylato(triphenylphosphine)rhodium(II) or dicarboxylato(substituted triphenylphosphine)rhodium(II) compound, in a reaction-inert solvent, produces the corresponding 6-deoxytetracycline compound. The hydrogenation takes place with a stereoselectivity which favors the 6.alpha.-isomer over the 6.beta.-isomer. The products are known antibacterial agents.

Abstract: A process for the preparation of methyl 3-(2-quinoxalinylmethylene)carbazate N.sup.1,N.sup.4 -dioxide which comprises contacting a 2-quinoxalinecarboxaldehyde N.sup.1,N.sup.4 -dioxide nitrone with at least about an equimolar proportion of methyl carbazate in acidic solvent medium until reaction is substantially complete.

Abstract: Catalyst produced by the process of reacting 1 mol of rhodium trichloride and 2 mols of sodium acetate in methanol at a temperature from about 50.degree.C. to the reflux temperature of said reaction mixture, then reacting resulting reaction mixture with 2 mols of triphenylphosphine at a temperature of from about 50.degree.C. to the reflux temperature of said reaction mixture and recovering resulting insoluble material and use thereof in hydrogenating 6-deoxy-6-demethy-6-methylene-5-oxytetracycline to obtain .alpha.-6-deoxy-5-oxytetracycline.

Abstract: A new process for the production of citric acid, and intermediates therefor of the formula: ##SPC1##Wherein R' is cyano or CO-R.sup.2, wherein R.sup.2 is lower alkoxy, amino or hydroxy.