Patents by Inventor Hermann Mueller-Boetticher

Hermann Mueller-Boetticher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of dabigatran etexilate
    Patent number: 8993770
    Abstract: An improved process for preparing dabigatran etexilate, as well as analogous compounds of formula 7, is described.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: March 31, 2015
    Assignee: Boehringer Ingelheim International GbmH
    Inventors: Frieder Gnad, Stefan Schmitt, Hermann Mueller-Boetticher, Helmut Heitger, Seigfried Meineck, Rolf Dach, Ingo Heddesheimer
  • PROCESS FOR THE MANUFACTURE OF DABIGATRAN ETEXILATE
    Publication number: 20130158270
    Abstract: An improved process for preparing dabigatran etexilate, as well as analogous compounds of formula 7, is described.
    Type: Application
    Filed: February 15, 2013
    Publication date: June 20, 2013
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Frieder GNAD, Stefan SCHMITT, Hermann MUELLER-BOETTICHER, Helmut HEITGER, Seigfried MEINECK, Rolf DACH, Ingo HEDDESHEIMER
  • Process for the manufacture of dabigatran etexilate
    Patent number: 8399678
    Abstract: An improved process for preparing dabigatran etexilate, as well as analogous compounds of formula 7, is described.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: March 19, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Frieder Gnad, Stefan Schmitt, Hermann Mueller-Boetticher, Helmut Heitger, Siegfried Meineck, Rolf Dach, Ingo Heddesheimer
  • PROCESS FOR THE MANUFACTURE OF DABIGATRAN ETEXILATE
    Publication number: 20110275824
    Abstract: An improved process for preparing dabigatran etexilate, as well as analogous compounds of formula 7, is described.
    Type: Application
    Filed: November 4, 2010
    Publication date: November 10, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Frieder GNAD, Stefan SCHMITT, Hermann MUELLER-BOETTICHER, Helmut HEITGER, Siegfried MEINECK, Rolf DACH, Ingo HEDDESHEIMER
  • Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
    Patent number: 6495694
    Abstract: A process for dynamically separating the enantiomers of a piperidone derivative of formula (1) wherein: R1 is aryl optionally mono- to polysubstituted, heteroaryl, which is linked to the chiral center via at least one carbon atom of its own or a carbon atom belonging to the methylene bridge, or straight-chain or branched C1-C8-alkyl optionally mono- to polysubstituted by halogen; R2 and R3, which are identical or different, are each straight-chain or branched C1-C6-alkyl; and n is 0, 1, 2 or 3, the process comprising: (a) dissolving an optically active acid and optionally catalytic amounts of a sulfonic acid in a solvent to make a first solution maintained at a desired temperature; (b) adding a second solution of the piperidone derivative to the first solution to precipitate out the desired enantiomer of the piperidone derivative as a salt of the optically active acid used while racemizing the unwanted enantiomer of the piperidone derivative in solution and further precipitating the de
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: December 17, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Hermann Mueller-Boetticher, Gerd-Rainer Bressler, Paul Kreye
  • Separation of the enantiomers of piperidone derivatives with simultaneous racemisation in situ of the unwanted enantiomer
    Publication number: 20020010336
    Abstract: A process for dynamically separating the enantiomers of a piperidone derivative of formula (1) 1
    Type: Application
    Filed: April 26, 2001
    Publication date: January 24, 2002
    Inventors: Hermann Mueller-Boetticher, Gerd-Rainer Bressler, Paul Kreye