Abstract: A computer system is disclosed comprising a processor arrangement communicatively coupled to a data storage arrangement storing a digital model of a section of a lumen system of a patient; and a communication module communicatively coupled to said processor arrangement and arranged to receive sensor data pertaining to an internal parameter of said lumen system from a sensor within said section of the lumen system. The processor arrangement is arranged to receive said sensor data from the communication module; retrieve said digital model from the data storage arrangement; simulate an actual physical condition of said lumen system by developing said digital model based on the received sensor data; and generate an output relating to said simulated actual physical condition for updating an electronic device. Also disclosed is a method of monitoring a patient with such a computer system, a computer program product for implementing such a method and a patient monitoring system.

Abstract: The present disclosure relates to a system for patient-specific intervention planning, the system comprising a physical model of an anatomical structure, wherein the physical model is a patient-specific model based on medical image data; a virtual model of the anatomical structure, wherein the virtual model is a patient-specific model based on medical image data; a tracking device configured to track a position of a physical representation of an interventional tool with respect to the physical model of the anatomical structure; a processor configured to perform the step of: registering the physical model of the anatomical structure with the virtual model of the anatomical structure and registering the physical representation of the interventional tool with a virtual representation of the interventional tool based on the position of the physical representation of the interventional tool and the physical model of the anatomical structure.

Abstract: A stress prediction device for predicting mechanical stress exerted to a deformable object due contact between the object and an external device that is to be inserted into the object at an intended insertion position comprises a segmentation unit configured to access generic model data representing a generic reference object that comprises predefined secondary landmark features at predefined landmark positions, which are not identifiable using a predefined imaging technique, and pre-insertion object image data acquired using the imaging technique. It provides segmented object model data which comprises associated mapped landmark position data indicative of mapped landmark positions of the secondary landmark features. A stress determination unit determines and provides predictive stress information indicative of mechanical stress exerted to at least one of the secondary landmark features at the associated mapped landmark position due to mechanical contact between the object and the external device.

Abstract: The invention provides a method for generating a non-invasive measure of blood vessel rigidity for a subject. The method includes obtaining 2D ultrasound data and 3D ultrasound data of the blood vessel from a given measurement location. The 2D ultrasound data provides information relating to a movement of the blood vessel and the 3D ultrasound data provides information relating to a shape of the blood vessel. A motion of the blood vessel is then determined based on the movement of the blood vessel. The method then includes providing the determined motion of the blood vessel, the shape of the blood vessel and an obtained non-invasive pressure measurement to a biomechanical model. A measure of rigidity is then determined based on the biomechanical model.

Abstract: A stress prediction device for predicting mechanical stress exerted to a deformable object due contact between the object and an external device that is to be inserted into the object at an intended insertion position comprises a segmentation unit configured to access generic model data representing a generic reference object that comprises predefined secondary landmark features at predefined landmark positions, which are not identifiable using a predefined imaging technique, and pre-insertion object image data acquired using the imaging technique. It provides segmented object model data which comprises associated mapped landmark position data indicative of mapped landmark positions of the secondary landmark features. A stress determination unit determines and provides predictive stress information indicative of mechanical stress exerted to at least one of the secondary landmark features at the associated mapped landmark position due to mechanical contact between the object and the external device.

Abstract: The present disclosure relates to a system for patient-specific intervention planning, the system comprising a physical model of an anatomical structure, wherein the physical model is a patient-specific model based on medical image data; a virtual model of the anatomical structure, wherein the virtual model is a patient-specific model based on medical image data; a tracking device configured to track a position of a physical representation of an interventional tool with respect to the physical model of the anatomical structure; a processor configured to perform the step of: registering the physical model of the anatomical structure with the virtual model of the anatomical structure and registering the physical representation of the interventional tool with a virtual representation of the interventional tool based on the position of the physical representation of the interventional tool and the physical model of the anatomical structure.

Abstract: The present invention relates to a device for predicting an unfolded state of a foldable implant in biological tissue, the device comprising: a receiving unit configured to receive pre -treatment 3D planning image data and treatment image data, the treatment image data comprising catheter image data, the catheter image data comprising landmark image data; a segmentation module configured to segment the pre-treatment 3D planning image data resulting in segmented 3D planning image data; a search unit configured to locate the landmark image data within the treatment image data resulting in a known landmark position and a known landmark orientation; a registration module configured to register the segmented 3D planning image data to the treatment image data resulting in registered treatment image data; and a simulation unit configured to simulate an unfolded state of a foldable implant in biological tissue based on the known landmark position and the known landmark orientation in the biological tissue resulting i

Abstract: A computer system is disclosed comprising a processor arrangement communicatively coupled to a data storage arrangement storing a digital model of a section of a lumen system of a patient; and a communication module communicatively coupled to said processor arrangement and arranged to receive sensor data pertaining to an internal parameter of said lumen system from a sensor within said section of the lumen system. The processor arrangement is arranged to receive said sensor data from the communication module; retrieve said digital model from the data storage arrangement; simulate an actual physical condition of said lumen system by developing said digital model based on the received sensor data; and generate an output relating to said simulated actual physical condition for updating an electronic device. Also disclosed is a method of monitoring a patient with such a computer system, a computer program product for implementing such a method and a patient monitoring system.

Abstract: The invention relates to a navigation assistance system for assisting in navigating an interventional instrument (10) within a subject during an interventional procedure. Based on a provided current position and shape of the interventional instrument, a provided target position defining the position of a target (45) to which the interventional instrument is to be moved and provided configuration information being indicative of possible configurations of the interventional instrument a possible path (50) is determined, which allows the interventional instrument to reach the target. The determined possible path and preferentially also the current position and shape of the interventional instrument and the target position can be shown on a display in realtime, while a physician moves the interventional instrument, thereby assisting the physician in navigating the interventional instrument.

Abstract: The success of the positioning of devices for deployment inside an aneurysm, for example, is reliant on processes, which take place within an intervention procedure. For example, the position, orientation, or trajectory of the intervention device can affect the final position of a device for deployment deployed on the intervention device. Therefore, it is useful to predict the deployment position of a device for deployment based on a current localization of only the intervention device within an object of interest.

Abstract: The success of the positioning of devices for deployment inside an aneurysm, for example, is reliant on processes,which take place within an intervention procedure. For example, the position, orientation, or trajectory of the intervention device can affect the final position of a device for deployment deployed on the intervention device. Therefore, it is useful to predict the deployment position of a device for deployment based on a current localization of only the intervention device within an object of interest.