Patents by Inventor Hernan Cuervo

Hernan Cuervo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomolecule conjugates
    Patent number: 10335495
    Abstract: The present invention relates to biomolecule conjugates which comprise a biomolecule wherein at least one non-natural amino acid (NNAA) is integral to the structure of the biomolecule and wherein the NNAA is a point of attachment of a linker to which a payload, particularly a cytotoxic agent, is attached. More specifically, this invention relates to conjugates of cell-binding agents and active release products comprising cytotoxic agents wherein the conjugates are produced by means of a cycloaddition reaction. Methods of production, pharmaceutical compositions and methods of use are provided.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: July 2, 2019
    Assignee: CELGENE CORPORATION
    Inventors: Eric Schwartz, Laura Akullian D'Agostino, Hernan Cuervo, Wesley Austin
  • BIOMOLECULE CONJUGATES
    Publication number: 20170360952
    Abstract: The present invention relates to biomolecule conjugates which comprise a biomolecule wherein at least one non-natural amino acid (NNAA) is integral to the structure of the biomolecule and wherein the NNAA is a point of attachment of a linker to which a payload, particularly a cytotoxic agent, is attached. More specifically, this invention relates to conjugates of cell-binding agents and active release products comprising cytotoxic agents wherein the conjugates are produced by means of a cycloaddition reaction. Methods of production, pharmaceutical compositions and methods of use are provided.
    Type: Application
    Filed: December 3, 2015
    Publication date: December 21, 2017
    Inventors: Eric Schwartz, Laura Akullian D'Agostino, Hernan Cuervo, Wesley Austin