Patents by Inventor Herndon Jenkins

Herndon Jenkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Methyleneazetidine derivatives
    Patent number: 4260606
    Abstract: This invention provides a novel class of 3-methyleneazetidines which include diphenylmethyl derivatives such as 1-isopropyl-3-diphenylmethyleneazetidine oxalate: ##STR1## This illustrated 3-methyleneazetidine compound is characterized by a combination of pharmacological properties which are indicative of utility as a mood elevating therapeutic agent for relieving the symptoms of depression in humans. The illustrated compound exhibits an ED.sub.50 (tetrabenazine-induced ptosis) of 2.18 mg/kg in mice.
    Type: Grant
    Filed: July 19, 1979
    Date of Patent: April 7, 1981
    Assignee: A. H. Robins Company, Inc.
    Inventors: Albert D. Cale, Jr., Herndon Jenkins
  • Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods
    Patent number: 4133881
    Abstract: .alpha.-(1-R-3-Azetidinyl)-.alpha.-phenyl-.alpha.-substituted-acetamides and -acetonitriles represented by the following formula: ##STR1## wherein R represents hydrogen, lower alkyl, lower cycloalkyl or phenyllower alkyl, R.sup.1 represents phenyl or 2-pyridyl, and Y is carbamoyl or cyano having antiarrhythmic activity are disclosed. Pharmaceutically acceptable acid addition salts of the free bases and quaternary salts are included as part of the invention.
    Type: Grant
    Filed: April 27, 1977
    Date of Patent: January 9, 1979
    Assignee: A. H. Robins Company, Incorporated
    Inventors: Albert D. Cale, Jr., Herndon Jenkins