Patents by Inventor Hershel Macaulay
Hershel Macaulay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250016288Abstract: An imaging device includes light sensitive locations that are separately sensitive to light received at a surface with respect to a portion of a sample associated with the surface, the light sensitive locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light sensitive locations are such that usable useful image of the portion of the sample can be acquired directly by operation of the imaging device. An imaging device includes light sensitive sources that are separately able to deliver light with respect to a portion of a sample associated with the surface. The light source locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface.Type: ApplicationFiled: May 13, 2024Publication date: January 9, 2025Inventors: Alan Marc Fine, Hershel Macaulay, Laurent Kreplak
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Patent number: 12022236Abstract: An imaging device includes light sensitive locations that are separately sensitive to light received at a surface with respect to a portion of a sample associated with the surface, the light sensitive locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light sensitive locations are such that usable useful image of the portion of the sample can be acquired directly by operation of the imaging device. An imaging device includes light sensitive sources that are separately able to deliver light with respect to a portion of a sample associated with the surface. The light source locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface.Type: GrantFiled: November 4, 2022Date of Patent: June 25, 2024Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Laurent Kreplak
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Patent number: 11874452Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: GrantFiled: March 16, 2022Date of Patent: January 16, 2024Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Patent number: 11598699Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: GrantFiled: August 14, 2020Date of Patent: March 7, 2023Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay
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Publication number: 20220225908Abstract: Systems, apparatuses and methods for the non-invasive measurement of a surrogate for a biomarker in a person's blood. In the example where the surrogate is a level of fat in the blood of the person and the biomarker is the level of triglycerides in the person's blood, the correlation between measurements of the surrogate and the level of triglycerides may be used to generate a recommendation to the person regarding a change in their intake of food, their exercise regimen, or another aspect of their lifestyle.Type: ApplicationFiled: January 21, 2022Publication date: July 21, 2022Applicant: NUEON INC.Inventors: Robert G. MESSERSCHMIDT, Hershel MACAULAY, Dara ROUHOLIMAN
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Publication number: 20220206282Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: ApplicationFiled: March 16, 2022Publication date: June 30, 2022Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Publication number: 20220142516Abstract: A blood sample collector can be used to collect a blood sample from a subject. The blood sample collector can be placed in a receptacle of a spectrometer to measure spectral data from the blood sample while the blood sample separates. The container may comprise a window to allow light such as infrared light to pass through the container, with the blood sample at least partially separating within the container between spectral measurements, which can provide improved accuracy of the measurements and additional information regarding the sample. Measurements of the level of a biomarker surrogate in a person's blood may be used to assist the person to make beneficial changes to their diet, exercise regimen, or other aspects of their lifestyle.Type: ApplicationFiled: October 19, 2021Publication date: May 12, 2022Applicant: NUEON INC.Inventors: Robert G. MESSERSCHMIDT, Hershel MACAULAY, Dara ROUHOLIMAN
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Publication number: 20200379234Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: ApplicationFiled: August 17, 2020Publication date: December 3, 2020Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Publication number: 20200371004Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: ApplicationFiled: August 14, 2020Publication date: November 26, 2020Inventors: Alan Marc Fine, Hershel Macaulay
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Patent number: 10809512Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: GrantFiled: June 27, 2019Date of Patent: October 20, 2020Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Patent number: 10768078Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: GrantFiled: March 28, 2019Date of Patent: September 8, 2020Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay
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Patent number: 10746979Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: GrantFiled: June 27, 2019Date of Patent: August 18, 2020Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Patent number: 10502666Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: GrantFiled: March 10, 2016Date of Patent: December 10, 2019Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay
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Patent number: 10459213Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: GrantFiled: June 1, 2018Date of Patent: October 29, 2019Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Publication number: 20190324258Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: ApplicationFiled: June 27, 2019Publication date: October 24, 2019Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Publication number: 20190317309Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: ApplicationFiled: June 27, 2019Publication date: October 17, 2019Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Publication number: 20190293524Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: ApplicationFiled: March 10, 2016Publication date: September 26, 2019Inventors: Alan Marc Fine, Hershel Macaulay
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Publication number: 20190242794Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.Type: ApplicationFiled: March 28, 2019Publication date: August 8, 2019Inventors: Alan Marc Fine, Hershel Macaulay
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Publication number: 20180284416Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: ApplicationFiled: June 1, 2018Publication date: October 4, 2018Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen
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Patent number: 9989750Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.Type: GrantFiled: November 23, 2016Date of Patent: June 5, 2018Assignee: Alentic Microscience Inc.Inventors: Alan Marc Fine, Hershel Macaulay, Noah Hymes-Vandermeulen