Patents by Inventor Herui Wang

Herui Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxabicycloheptanes for modulation of immune response
    Patent number: 12168008
    Abstract: The present invention provides a method of treating a subject afflicted with cancer comprising administering to the subject an effective amount of a PP2A inhibitor.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: December 17, 2024
    Assignees: Lixte Biotechnology, Inc., The United States of America, as Represented by the Secretary Department of Health and Human Services
    Inventors: John S. Kovach, Zhengping Zhuang, Sze Chun Winson Ho, Herui Wang, Rongze Lu
  • CANCER VACCINE AND METHOD OF USE THEREOF
    Publication number: 20240148855
    Abstract: The present disclosure generally relates to a personalized cancer vaccine having attenuated cancer cells transfected with at least one expression construct. The expression construct is capable of secretory expression of an antigenic polypeptide that could be derived from a protein from a virus. The personalized tumor vaccine, when administered to a subject in need thereof, is effective to activate an immune response.
    Type: Application
    Filed: March 14, 2022
    Publication date: May 9, 2024
    Inventors: Zhengping ZHUANG, Herui WANG, Juan YE, Bin LU
  • PERSONALIZED TUMOR VACCINE AND USE THEREOF FOR CANCER IMMUNOTHERAPY
    Publication number: 20230054318
    Abstract: Disclosed herein is a personalized tumor vaccine comprising attenuated cancer cells and a method of using said personalized tumor vaccine to treat cancer.
    Type: Application
    Filed: December 11, 2020
    Publication date: February 23, 2023
    Inventors: Zhengping Zhuang, Rogelio Medina, Herui Wang, Jan Zenka, Karel Pacak, Winson Ho
  • TP5, A PEPTIDE INHIBITOR OF ABERRANT AND HYPERACTIVE CDK5/P25 AS TREATMENT FOR CANCER
    Publication number: 20220009980
    Abstract: Methods of decreasing cell viability of cancer cells, increasing apoptosis of cancer cells, and treating cancer in a mammal with cancer are provided. The methods include administering (i) a polypeptide comprising an amino acid sequence with at least 95% sequence identity to the amino acid sequence of SEQ ID NO: 1, (ii) a nucleic acid molecule comprising a nucleic acid sequence encoding the polypeptide, (iii) a vector comprising the nucleic acid molecule, (iv) a recombinant cell comprising any one of (i)-(iii), and/or (v) a composition comprising any one of (i)-(iv).
    Type: Application
    Filed: November 13, 2019
    Publication date: January 13, 2022
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Zhengping Zhuang, Emeline Tabouret, Herui Wang, Harish Pant, Niranjana D. Amin
  • OXABICYCLOHEPTANES FOR MODULATION OF IMMUNE RESPONSE
    Publication number: 20200069680
    Abstract: The present invention provides a method of treating a subject afflicted with cancer comprising administering to the subject an effective amount of a PP2A inhibitor.
    Type: Application
    Filed: December 8, 2017
    Publication date: March 5, 2020
    Inventors: John S. Kovach, Zhengping Zhuang, Sze Chun Winson Ho, Herui Wang, Rongze Lu